Results 11 to 20 of about 52,056 (190)

The mysterious microcircuitry of the cerebellar nuclei

The Journal of Physiology, 2011
Abstract  The microcircuitry of cerebellar cortex and, in particular, the physiology of its main element, the Purkinje neuron, has been extensively investigated and described. However, activity in Purkinje neurons, either as single cells or populations, does not directly mediate the cerebellar effects on the motor effector systems.
Uusisaari, Marylka, De Schutter, Erik
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Preserved Glucose Metabolism of Deep Cerebellar Nuclei in a Case of Multiple System Atrophy with Predominant Cerebellar Ataxia: F-18 Fluorodeoxyglucose Positron Emission Tomography Study [PDF]

Journal of Movement Disorders, 2010
The cerebellar glucose metabolism of multiple system atrophy with predominant cerebellar ataxia (MSA-C) is known to be decreased but is not defined among areas of cerebellum. We encountered a 54-year-old man who developed dizziness and progressive ataxia
Oh Dae Kwon, Chang-Seok Ki
doaj   +2 more sources

Vascularisation of the cerebellar nuclei in Akkaraman sheep

Acta Veterinaria Hungarica, 2003
This study reports an anatomical study of the vascular supply in 20 Akkaraman sheep cerebelli from adult subjects of both sexes. The origin and branching pattern of the cerebellar artery vascularising the cerebellar nuclei were studied by gross dissection and vascular injection. Then dissection was performed and vessels nourishing the cerebellar nuclei
Yildiz, D., Gultiken, M. E.
openaire   +4 more sources

Cross-talk between dopamine and noradrenaline modulates glutamatergic transmission in the deep cerebellar nuclei [PDF]

Scientific Reports
Modulation of synaptic transmission in the deep cerebellar nuclei, a major output region of the cerebellum, is essential for regulating motor and non-motor functions by controlling information flow from the cerebellar cortex.
Fumihito Saitow, Ryosuke Arakawa, Hidenori Suzuki   +2 more
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Bilateral representation in the deep cerebellar nuclei

The Journal of Physiology, 2008
The cerebellum is normally assumed to represent ipsilateral movements. We tested this by making microelectrode penetrations into the deep cerebellar nuclei (mainly nucleus interpositus) of monkeys trained to perform a reach and grasp task with either hand.
Soteropoulos D, Baker S
openaire   +5 more sources

Diffusion spectrum imaging shows the structural basis of functional cerebellar circuits in the human cerebellum in vivo. [PDF]

PLoS ONE, 2009
The cerebellum is a complex structure that can be affected by several congenital and acquired diseases leading to alteration of its function and neuronal circuits.
Cristina Granziera, Jeremy Dan Schmahmann, Nouchine Hadjikhani, Heiko Meyer, Reto Meuli, Van Wedeen, Gunnar Krueger   +6 more
doaj   +1 more source

Glutamatergic cerebellar neurons differentially contribute to the acquisition of motor and social behaviors

Nature Communications, 2023
Insults to the developing cerebellum can cause motor, language, and social deficits. Here, we investigate whether developmental insults to different cerebellar neurons constrain the ability to acquire cerebellar-dependent behaviors. We perturb cerebellar
Meike E. van der Heijden, Alejandro G. Rey Hipolito, Linda H. Kim, Dominic J. Kizek, Ross M. Perez, Tao Lin, Roy V. Sillitoe   +6 more
doaj   +1 more source

Age-related differences of cerebellar cortex and nuclei: MRI findings in healthy controls and its application to spinocerebellar ataxia (SCA6) patients

NeuroImage, 2023
Understanding cerebellar alterations due to healthy aging provides a reference point against which pathological findings in late-onset disease, for example spinocerebellar ataxia type 6 (SCA6), can be contrasted. In the present study, we investigated the
Dominik Jäschke, Katharina M. Steiner, Dae-In Chang, Jens Claaßen, Ellen Uslar, Andreas Thieme, Marcus Gerwig, Viktor Pfaffenrot, Thomas Hulst, Alexander Gussew, Stefan Maderwald, Sophia L. Göricke, Martina Minnerop, Mark E. Ladd, Jürgen R. Reichenbach, Dagmar Timmann, Andreas Deistung   +16 more
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The underpinnings of cerebellar ataxias

Clinical Neurophysiology Practice, 2022
The human cerebellum contains more than 60% of all neurons of the brain. Anatomically, the cerebellum is divided into 10 lobules (I-X). The cerebellar cortex is arranged into three layers: the molecular layer (external), the Purkinje cell layer and the ...
Mario Manto
doaj   +1 more source

N-acetylgalactosamine positive perineuronal nets in the saccade-related-part of the cerebellar fastigial nucleus do not maintain saccade gain. [PDF]

PLoS ONE, 2014
Perineuronal nets (PNNs) accumulate around neurons near the end of developmental critical periods. PNNs are structures of the extracellular matrix which surround synaptic contacts and contain chondroitin sulfate proteoglycans.
Adrienne Mueller, Adam Davis, Steven S Carlson, Farrel R Robinson   +3 more
doaj   +1 more source