Results 91 to 100 of about 461,280 (380)
Cerebellar defects in Pdss2 conditional knockout mice during embryonic development and in adulthood
Neurobiology of Disease, 2012 PDSS2 is a gene that encodes one of the two subunits of trans-prenyl diphosphate synthase that is essential for ubiquinone biosynthesis. It is known that mutations in PDSS2 can cause primary ubiquinone deficiency in humans and a similar disease in mice ...
Song Lu +6 more
doaj +1 more source
Prevalence of Stroke and Diagnostic Performance of Emergency MRI in Acute Isolated Dizziness
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Stroke is frequently misdiagnosed in patients presenting with acute isolated dizziness; the optimal imaging modality for this population remains debated. This study aimed to determine the prevalence of stroke among patients with isolated dizziness and to assess the diagnostic accuracy of magnetic resonance imaging (MRI) and computed ...
Xiao Hu +11 more
wiley +1 more source
ATXN2-CAG42 sequesters PABPC1 into insolubility and induces FBXW8 in cerebellum of old ataxic knock-in mice [PDF]
, 2012 Spinocerebellar Ataxia Type 2 (SCA2) is caused by expansion of a polyglutamine encoding triplet repeat in the human ATXN2 gene beyond (CAG)31. This is thought to mediate toxic gain-of-function by protein aggregation and to affect RNA processing ...
Auburger, Georg +8 more
core +3 more sources
Computational Principles of Supervised Learning in the Cerebellum.
Annual Review of Neuroscience, 2018 Supervised learning plays a key role in the operation of many biological and artificial neural networks. Analysis of the computations underlying supervised learning is facilitated by the relatively simple and uniform architecture of the cerebellum, a ...
J. Raymond, J. Medina
semanticscholar +1 more source
THE FUNCTION OF THE CEREBELLUM [PDF]
The Journal of Nervous and Mental Disease, 1922 n ...
openaire +1 more source
The Cerebellum and Migraine [PDF]
Headache: The Journal of Head and Face Pain, 2007 Clinical and pathophysiological evidences connect migraine and the cerebellum. Literature on documented cerebellar abnormalities in migraine, however, is relatively sparse. Cerebellar involvement may be observed in 4 types of migraines: in the widespread migraine with aura (MWA) and migraine without aura (MWoA) forms; in particular subtypes of migraine
Maurice Vincent, Nouchine Hadjikhani
openaire +3 more sources
PLoS ONE, 2018 BackgroundBotulinum toxin type A (BoNT-A) is generally considered safe and is widely used to treat a variety of clinical conditions involving muscle hyperactivity and for cosmetic purposes.
Ge-Fei Li +15 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Cognitive impairment, fatigue, and depression are common in multiple sclerosis (MS), potentially due to disruption of regional functional connectivity caused by white matter (WM) lesions. We explored whether WM lesions functionally connected to specific brain regions contribute to these MS‐related manifestations.
Alessandro Franceschini +7 more
wiley +1 more source
The Cerebellum and SIDS: Disordered Breathing in a Mouse Model of Developmental Cerebellar Purkinje Cell Loss during Recovery from Hypercarbia. [PDF]
, 2016 The cerebellum assists coordination of somatomotor, respiratory, and autonomic actions. Purkinje cell alterations or loss appear in sudden infant death and sudden death in epilepsy victims, possibly contributing to the fatal event. We evaluated breathing
Calton, Michele A +4 more
core +2 more sources
Cerebellum, Predictions and Errors
Frontiers in Cellular Neuroscience, 2019 Making predictions and validating the predictions against actual sensory information is thought to be one of the most fundamental functions of the nervous system.
Laurentiu S. Popa, T. Ebner
semanticscholar +1 more source