Results 91 to 100 of about 354,424 (374)

Further expansion and confirmation of phenotype in rare loss of YWHAE gene distinct from Miller–Dieker syndrome

open access: yesAmerican Journal of Medical Genetics Part A, Volume 191, Issue 2, Page 526-539, February 2023., 2023
Abstract Deletion of 17p13.3 has varying degrees of severity on brain development based on precise location and size of the deletion. The most severe phenotype is Miller–Dieker syndrome (MDS) which is characterized by lissencephaly, dysmorphic facial features, growth failure, developmental disability, and often early death.
Elizabeth K. Baker   +9 more
wiley   +1 more source

Selective recruitment of the cerebellum evidenced by task-dependent gating of inputs

open access: yeseLife
Functional magnetic resonance imaging (fMRI) studies have documented cerebellar activity across a wide array of tasks. However, the functional contribution of the cerebellum within these task domains remains unclear because cerebellar activity is often ...
Ladan Shahshahani   +4 more
doaj   +1 more source

Regional Heterogeneity of Cerebral Microvessels and Brain Susceptibility to Oxidative Stress. [PDF]

open access: yesPLoS ONE, 2015
The hippocampus is one of the earliest and most affected regions in Alzheimer's disease (AD), followed by the cortex while the cerebellum is largely spared. Importantly, endothelial dysfunction is a common feature of cerebral blood vessels in AD. In this
Susan A Austin   +3 more
doaj   +1 more source

Regional distribution of the prostaglandin E2 receptor EP1 in the rat brain: accumulation in Purkinje cells of the cerebellum [PDF]

open access: yesJournal of Molecular Neuroscience 27(3): 303-310 (2005), 2007
Prostaglandin E2 (PGE2), is a major prostanoid produced by the activity of cyclooxygenases (COX) in response to various physiological and pathological stimuli. PGE2 exerts its effects by activating four specific E-type prostanoid receptors (EP1, EP2, EP3, and EP4).
arxiv  

Adaptive Neural Models of Queuing and Timing in Fluent Action [PDF]

open access: yes, 2003
Temporal structure in skilled, fluent action exists at several nested levels. At the largest scale considered here, short sequences of actions that are planned collectively in prefrontal cortex appear to be queued for performance by a cyclic competitive ...
Bullock, Daniel
core   +1 more source

AN ANGIOMA OF THE CEREBELLUM [PDF]

open access: yesThe Journal of Nervous and Mental Disease, 1915
n ...
openaire   +2 more sources

Dual‐Phase C‐11 PiB PET Images for Detecting Tau Pathology in Cerebral Amyloid Angiopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cerebral amyloid angiopathy (CAA) is a major cause of lobar intracerebral hemorrhage and cognitive dysfunction in the elderly, and frequently coexists with Alzheimer's disease and tau pathology. Dual‐phase 11C‐PiB PET detects amyloid deposition and cerebral perfusion changes and may have diagnostic value for identifying tau in CAA ...
Meng‐Ting Chiang   +4 more
wiley   +1 more source

Brain functional changes in patients with botulism after illegal cosmetic injections of botulinum toxin: A resting-state fMRI study.

open access: yesPLoS ONE, 2018
BackgroundBotulinum toxin type A (BoNT-A) is generally considered safe and is widely used to treat a variety of clinical conditions involving muscle hyperactivity and for cosmetic purposes.
Ge-Fei Li   +15 more
doaj   +1 more source

Mild Neonatal Brain Hypoxia-Ischemia in Very Immature Rats Causes Long-Term Behavioral and Cerebellar Abnormalities at Adulthood

open access: yesFrontiers in Physiology, 2019
Systemic hypoxia-ischemia (HI) often occurs during preterm birth in human. HI induces injuries to hinder brain cells mainly in the ipsilateral forebrain structures.
Eduardo Farias Sanches   +5 more
doaj   +1 more source

Altered cerebellar-cerebral functional connectivity in geriatric depression. [PDF]

open access: yesPLoS ONE, 2011
Although volumetric and activation changes in the cerebellum have frequently been reported in studies on major depression, its role in the neural mechanism of depression remains unclear.
Emmanuel Alalade   +4 more
doaj   +1 more source

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