Results 141 to 150 of about 461,280 (380)

Optoacoustic‐Guided Magnetic Microrobot Platform for Precision Drug Delivery

open access: yesAdvanced Materials, EarlyView.
Optoacoustically guided FePt@ZIF‐8‐based microrobots are designed with high drug loading capacity, controllable locomotion, and deep‐tissue imaging capability. By integrating navigation, drug release, and real‐time monitoring into a single platform, they provide a versatile tool for precise intervention, opening new possibilities for treating ...
Fan Wang   +12 more
wiley   +1 more source

A Scalable Model of Cerebellar Adaptive Timing and Sequencing: The Recurrent Slide and Latch (RSL) Model [PDF]

open access: yes, 2000
From the dawn of modern neural network theory, the mammalian cerebellum has been a favored object of mathematical modeling studies. Early studies focused on the fan-out, convergence, thresholding, and learned weighting of perceptual-motor signals within ...
Bullock, Daniel, Rhodes, Bradley
core   +1 more source

Cerebellar-cerebral circuits functional connectivity in patients with cognitive impairment after basal ganglia stroke: a pilot study

open access: yesFrontiers in Aging Neuroscience
IntroductionThis study aims to assess the pattern of functional connectivity (FC) between cerebellar subregions, the basal ganglia (BG), and the cortex, and explore the relationship between FC patterns and cognitive function after stroke with BG infarcts.
Lijun Zuo   +9 more
doaj   +1 more source

Loss of Fibronectin Fiber Tension in Glioblastoma is Associated with Microvascular Proliferations and Immune Cell Infiltration

open access: yesAdvanced Science, EarlyView.
Researchers discovered that fibronectin fibers lose their tension in specific areas of glioblastoma brain tumors, accumulating in the lumen of proliferating blood vessels and in parenchyma next to infiltrating immune cell clusters. A novel molecular tension probe enables the mapping of fibronectin's fiber tension in glioblastoma for the first time ...
Michele Crestani   +6 more
wiley   +1 more source

Papel do cerebelo nas funções cognitivas e comportamentais: bases científicas e modelos de estudo.

open access: yesActa Médica Portuguesa, 2006
Although classically considered to be involved only in motor coordination, the cerebellum has more recently been implicated also in cognitive control.
Paulo Bugalho   +2 more
doaj   +1 more source

Pigment Epithelium‐Derived Factor Deficiency Impairs Hippocampal Glutamate Homeostasis and Cognitive Function by Downregulating Astrocytic GLT‐1

open access: yesAdvanced Science, EarlyView.
The chronic glutamate‐induced excitotoxicity hypothesis has profoundly informed the therapeutic strategies employed in Alzheimer’s disease (AD). This study shows pigment epithelium‐derived factor (PEDF) regulates astrocytic glutamate transporter‐1 (GLT‐1)‐mediated glutamate homeostasis and cognition. Reduced PEDF correlates with lower Mini‐Mental State
Jin‐Hui Shi   +15 more
wiley   +1 more source

A Working Hypothesis for the Role of the Cerebellum in Impulsivity and Compulsivity

open access: yesFrontiers in Behavioral Neuroscience, 2019
Growing evidence associates cerebellar abnormalities with several neuropsychiatric disorders in which compulsive symptomatology and impulsivity are part of the disease pattern.
M. Miquel   +4 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy