Results 241 to 250 of about 354,424 (374)
QUANTITATIVE ANALYSIS OF CELL PROLIFERATION AND DIFFERENTIATION IN THE CORTEX OF THE POSTNATAL MOUSE CEREBELLUM [PDF]
Setsuya Fujita
openalex +1 more source
Objective The objective is to evaluate cognitive and behavioral progression and identify early predictors of these changes in a cohort of amyotrophic lateral sclerosis (ALS) patients. Methods A total of 161 ALS patients were tested at diagnosis (T0), and 107 were re‐tested after 1 year (T1) using cognitive/behavioral tests. All patients underwent whole‐
Barbara Iazzolino+13 more
wiley +1 more source
New Transferrin Receptor‐Targeting Conjugate Effectively Delivers DNA to Mouse Brain
We present a novel RNA aptamer targeting the transferrin receptor (TfR), conjugated with DSPE lipid, which achieves remarkably efficient brain uptake, reaching brain‐to‐serum ratios as high as 6.5. Through fluorescence imaging and polymerase‐chain reaction analyses, we verify that this new conjugate successfully delivers a substantial amount of DNA ...
Min‐sun Song+8 more
wiley +2 more sources
Brain connectomics markers for response prediction to transcranial magnetic stimulation in cocaine use disorder. [PDF]
Ghazi N+2 more
europepmc +1 more source
Objective Accurate personalized survival prediction in amyotrophic lateral sclerosis is essential for effective patient care planning. This study investigates whether grey and white matter changes measured by magnetic resonance imaging can improve individual survival predictions.
Isabelle Lajoie+3 more
wiley +1 more source
Saturated fatty acids induce insulin resistance in neurons. Neuronal metabolism of palmitic acid alters mitochondrial function. Abstract Introduction Saturated fatty acids (FAs) are the main component of high‐fat diets (HFDs), and high consumption has been associated with the development of insulin resistance, endoplasmic reticulum stress and ...
Karina Sánchez‐Alegría+1 more
wiley +1 more source
Optimising Electrode Montages in Conventional Transcranial Direct Current Stimulation and High-Definition Transcranial Direct Current Stimulation of the Cerebellum for Pain Modulation. [PDF]
Farnell Sharp A, Witney A.
europepmc +1 more source
Brain Metabolic Features of FUS‐ALS: A 2‐[18F]FDG‐PET Study
Objective We aimed at evaluating the brain metabolic features of fused in sarcoma amyotrophic lateral sclerosis (FUS‐ALS) compared with sporadic ALS (sALS), using 2‐[fluorine‐18] fluoro‐2‐deoxy‐D‐glucose positron emission tomography (2‐[18F]FDG‐PET). Methods We employed the 2‐sample t‐test model of SPM12, implemented in MATLAB, to compare 12 FUS‐ALS ...
Antonio Canosa+24 more
wiley +1 more source
Effects of depression and anxiety symptoms on cognitive inhibition: A cross-sectional study of structural and functional MRI evidence. [PDF]
Bahri M+4 more
europepmc +1 more source