Results 251 to 260 of about 368,839 (349)

Cerebellar and subcortical contributions to working memory manipulation. [PDF]

open access: yesCommun Biol
Tan JB   +9 more
europepmc   +1 more source

Senkyunolide I Improves Septicemia‐Induced Brain Dysfunction via Regulating Nrf2 and Astrocyte Activity.

open access: yesBiotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Senkyunolide I (Sen I) has a protective effect on the blood–brain barrier (BBB) in rats with sepsis‐associated encephalopathy (SAE). This study investigated whether Sen I regulates Nrf2 to ameliorate sepsis‐induced brain dysfunction (SIBD). Sixty rats were randomly assigned into Sham group, SAE group (Model group), SAE + Sen I group (72 mg/kg,
Haohao Cao, Tao Liu, Meixia Xu
wiley   +1 more source

Novel Sulfonylhydrazones With Sulfonate Ester Framework: Promising Dual Inhibitors of AChE and hCAs

open access: yesBiotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative disorder that affects millions of individuals worldwide. Treatment strategies for AD vary depending on cognitive and behavioral symptoms, with cholinergic replacement therapy using acetylcholinesterase (AChE) inhibitors being one of the primary approaches.
Cansu Öztürk   +3 more
wiley   +1 more source

CNS methylation classifiers may misclassify normal developing cerebellar cortex as medulloblastoma. [PDF]

open access: yesActa Neuropathol
Cotter JA   +6 more
europepmc   +1 more source

Credibility of genetic predictors for antiepileptic drug resistance: A systematic Bayesian reappraisal of published meta‐analyses

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
We systematically reappraised meta‐analyses of pharmacogenetic studies to evaluate the credibility of association between gene polymorphisms and resistance to anti‐epileptic drugs (AEDs). A systematic search was performed in PubMed, Web of Knowledge, Cochrane Library and OpenGrey up to April 2025.
Martina Giacon   +2 more
wiley   +1 more source

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