ABSTRACT Post‐translational modifications (PTMs) to tubulin subunits in microtubule filaments are thought to comprise a component of the tubulin code that specifies microtubule functions in cell physiology and animal development. Acetylation of Lysine‐40 (K40) on α‐tubulin (αTub‐K40ac) and glutamylation of both α‐ and β‐tubulin are two tubulin PTMs of ...
Lynne Blasius+6 more
wiley +1 more source
The alteration of the sensorimotor network in trigeminal neuralgia after microvascular decompression surgery: a follow-up study using independent component analysis. [PDF]
Zhang Y, Wang X, Wang X, Huang G.
europepmc +1 more source
NSAIDS AS MODULATORS OF CATION CHANNELS: FENAMATES REPURPOSING IN CHANNELOPATHIES
Cationic ion channels are transmembrane proteins that regulate the flux of cations (potassium, sodium, and calcium) across cell membrane, playing a pivotal role in many cellular functions. Disruptions of their activity can lead to the so‐called genetic or acquired channelopathies, a heterogeneous group of diseases that affect multiple human systems ...
Paola Laghetti+4 more
wiley +1 more source
Sex-Associated Cerebellar and Hippocampal Volume Reduction in Alzheimer's Disease: Insights from the Clinical ADNI Cohort and STZ Animal Model. [PDF]
Wartchow KM+10 more
europepmc +1 more source
Manganese Neurotoxicity and Familial Disorders of Manganese Transport
ABSTRACT Manganese is the 12th most common element in the Earth's crust and is an essential industrial component. Biologically, this metal plays an important role as a constituent of numerous enzymes. While manganese is required for normal biochemical and physiological processes, manganese excess can lead to significant toxicity, particularly to the ...
Sidney M. Gospe Jr.
wiley +1 more source
Characterization of experimental cerebral malaria by volumetric MRI A comparative study across the sexes. [PDF]
Comino Garcia Muñoz A+6 more
europepmc +1 more source
HISTOPATHOLOGICAL STUDY ON DEGENERATIVE CHANGES OF CEREBELLUM
Syoichi Sato
openalex +2 more sources
ABSTRACT Objective Possible pleiotropic effects of apolipoprotein E4 (APOE E4) in individuals with congenital brain malformations are relatively unknown. Our goal was to determine if neurodegeneration‐linked brain region volumes differ significantly between E4 carriers and noncarriers in young adults with spina bifida (SB). Methods Eleven individuals (
Joan M. Jasien+8 more
wiley +1 more source
Descending telencephalic information reaches longitudinal torus and cerebellum via the dorsal preglomerular nucleus in the teleost fish, Pantodon buchholzi [PDF]
Roth, G., Wullimann, Mario F.
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