Results 221 to 230 of about 6,798,168 (311)

PolyG Fibrils Coalesce Into Nuclear Ribbons That Engage Proteostasis Machinery in Neuronal Intranuclear Inclusion Disease

Advanced Science, EarlyView.
In NIID, expanded NOTCH2NLC repeats give rise to nuclear polyG inclusions. Tracer‐guided in situ cryo‐electron tomography enables cross‐scale structural analysis from mouse brain to native neuronal nuclei, revealing dense‐core/peripheral‐halo inclusions built from compact polyG ribbons.
Hui Dong, Yongcheng Pan, Zhiyao Tang, Yuxuan Yao, Guicong Zhang, Junpu Wang, Haonan Xiao, Yun Tian, Beisha Tang, Dan Li, Qiang Guo, Ruijun Tian, Qiong Liu, Cong Liu   +13 more
wiley   +1 more source

Ejaculation-Triggered Reversible Cerebral Vasoconstriction Syndrome: A Case Report with Longitudinal Neuroimaging. [PDF]

Diagnostics (Basel)
Hayashi K, Ito Y, Sato M, Nakaya Y, Takehara T, Suzuki A, Miura T, Hayashi K, Kobayashi Y.   +8 more
europepmc   +1 more source

Targeting of Endothelial Activation in Cerebral Malaria

PLoS Medicine, 2005
openaire   +3 more sources

Self‐Assembly of Antigenic Peptide Nanofibrils Templates the Growth of Silica Nanoparticles for Nanovaccines

Advanced Science, EarlyView.
Antigenic peptides Aβ42 and E7 self‐assemble into nanofibrils; APTES and TEOS induce SiO2 NP formation on these fibrils to form SiO2@fibril nanovaccines, which activate BMDCs in vitro. In vivo, SiO2@Aβ42 fibril nanovaccines alleviate AD symptoms and clear Aβ42 plaques in APP/PS1 mice, and SiO2@E7 fibril nanovaccines inhibit tumor growth and promote ...
Xuecheng Yang, Min Li, Zhiying Yao, Yu Hu, Zhili Wang, Wendi Shi, Bingbing Sun   +6 more
wiley   +1 more source

Preserving Motor Features by Alternative Re‐Referencing to Remove Heart Artifact on the Stentrode

Advanced Science, EarlyView.
Endovascular brain‐computer interfaces record neural activity from within cerebrovasculature, at the expense of electrocardiogram contamination. Band‐limited independent component analysis separates this heart‐based artifact from task‐relevant neural activity in each frequency band, enabling the reconstruction of cleaner neural recordings without the ...
Ariel K. Feldman, Kriti Kacker, Rahyun Yun, Nikole Chetty, James Bennett, Peter E. Yoo, Raul G. Nogueira, Jennifer L. Collinger, Nicholas L. Opie, Thomas J. Oxley, David F. Putrino, Douglas J. Weber   +11 more
wiley   +1 more source

Patterns of habitual physical activity in children and adolescents with cerebral palsy (GMFCS I-II). [PDF]

Front Sports Act Living
Tørring MF, Roeleveld K, Lydersen S, Bardal EM, Brændvik SM.   +4 more
europepmc   +1 more source

HD‐tDCS Restores Perivascular AQP4 Polarization via PPARγ Modulation to Enhance Glymphatic Clearance After Intracerebral Hemorrhage in Mice

Advanced Science, EarlyView.
HD‐tDCS promotes recovery after intracerebral hemorrhage by enhancing PPARγ‐dependent astrocyte remodeling in a mouse model of ICH. This process suppresses proinflammatory astrocytic activation, restores perivascular AQP4 repolarization, and improves glymphatic influx and efflux, thereby facilitating hematoma and perihematomal edema clearance and ...
Zhiming Li, Yingmei Zhang, Qianqian Tong, Zhitao Gong, Shanyu Zhang, Zhen Qian, Hui Zhang, Qian Yao, Qi Li   +8 more
wiley   +1 more source

Prevalence and clinical associations of cerebral atrophy in systemic lupus erythematosus. [PDF]

Lupus Sci Med
Teo WS, Ng CM, Pok LSL, Fadzli F, Rahmat K, Raja J.   +5 more
europepmc   +1 more source

Gut Microbial Release of Ferulic Acid From Germinated Quinoa Alleviates Obesity‐Associated Cognitive Impairment by Activating Hippocampal Mitophagy Associated with PINK1/Parkin Pathway

Advanced Science, EarlyView.
Liberation of ferulic acid by gut microbial feruloyl esterase mediates cognitive enhancement of germinated quinoa (GQF) on obese mice. Ferulic acid enriched in GQF is released by gut microbes Roseburia hominis and R. intestinalis and subsequently mediates the neuroprotective effects of GQF on obesity‐induced cognitive decline by activating hippocampal ...
Yongli Lan, Wengang Zhang, Lei Wang, Shiyang Zhao, Yujie Song, Xinze Wang, Yutang Wang, Xijuan Yang, Shaobo Ma, Junlin Ge, Rui Guo, Xuebo Liu   +11 more
wiley   +1 more source

Cerebral oxygen extraction fraction as an emerging imaging biomarker in mild cognitive impairment and dementia. [PDF]

Dement Neuropsychol
Hussain JM, Lashari A, Nageen W, Siddiqui A, Waris A, Maliha S, Mudasir A, Rehman MBA, Rahman MHU.   +8 more
europepmc   +1 more source