Results 241 to 250 of about 6,798,168 (311)

ICOS‐ImmunoPET Monitors T Cell Activation After Combination Immune Checkpoint Blockade in a Mouse Model of Melanoma Brain Metastasis

Advanced Science, EarlyView.
ICOS‐immunoPET noninvasively visualizes activated T cells in melanoma brain metastases following combined anti‐PD‐1/anti‐CTLA‐4 therapy. Clinical translation of this imaging approach may improve patient stratification and treatment monitoring and serve as a quantitative imaging endpoint to support immunotherapy development and clinical trials in brain ...
Renesmee C. Kuo, Rohit Verma, Sydney C. Nagy, Mausam Kalita, Samuel Aubert, Josué Ballesteros‐Álvarez, Pedro Machado Almeida, Hannes Vogel, Israt S. Alam, Michael Lim, Michelle L. James   +10 more
wiley   +1 more source

GenX exposure induces neurodevelopmental impairment and synaptic toxicity in hESC-derived cerebral organoids. [PDF]

Mater Today Bio
Hyun SA, Lee YJ, Ko MY, Min E, Park H, Kim Y, Hwang DY, Lee BS, Ka M.   +8 more
europepmc   +1 more source

Rocket‐Inspired Sequentially Targeted Nanotherapeutics for Mitochondrial Regulation and Inflammatory Reprogramming in Ischemic Stroke

Advanced Science, EarlyView.
A novel neutrophil‐hitchhiking, rocket‐inspired nanoplatform is developed to cross the blood‐brain barrier for sequential, spatiotemporal drug delivery. By responsive surface transformation in the ischemic penumbra, it precisely targets mitochondria to suppress Drp1‐mediated fission.
He Bai, Zihao Yong, Yang Li, Qingmin Chen, Yong Liu, Xiaomeng Guo, Fukai Li, Shicheng Tang, Zhuo Yang, Yufei Zhang, Ruwei Jie, Xiaohong Lv, Huacheng Wang, Chunming Huang, Liwei Xie, Jianqi Xiao, Qingchun Mu, Longguang Tang   +17 more
wiley   +1 more source

The microdialysis-derived lactate-pyruvate gradient indicates anaerobic activity after brain injury. [PDF]

J Cereb Blood Flow Metab
Baker MS, Heihre JM, Kuliński T, Smith CA, Barlas B, Zimphango C, Timofeev I, Baranes K, Carpenter KLH, Kotter M, Guilfoyle MR, Rostami E, Hutchinson PJ, Helmy A.   +13 more
europepmc   +1 more source

Association Between the 6-Min Walk Test and Cardiopulmonary Exercise Testing Parameters in Subacute Cerebral Infarction. [PDF]

Brain Sci
Qie J, Zhao X, Gu Y, Du J, Ma X.
europepmc   +1 more source

Impact of neurovascular coupling and glymphatic function on cognitive function in asymptomatic cerebral small vessel disease. [PDF]

Front Neurol
Chen J, Wang Y, Chen X, Chen C, Shi W, Ding J.   +5 more
europepmc   +1 more source

Exercise as a Systemic Prevention and Management for Alzheimer's Disease: Restoring Brain-Body Homeostasis Through Metabolic, Neurovascular, Anti-Inflammatory, and Regenerative Mechanisms. [PDF]

Cells
Xiao L, Green JM, Mochizuki M, Nakahara T.   +3 more
europepmc   +1 more source

Icariside II in Neurological Disorders: Mechanistic Insights Into Alzheimer's Disease, Cerebral Ischemia and Parkinson's Disease. [PDF]

J Biochem Mol Toxicol
Solanki A, Sharma K, Jain J, Singh NK, Krishnamurthy PT.   +4 more
europepmc   +1 more source

Cortical neuromodulation by vibration-induced illusion of movement is observed in older individuals, but not in individuals with acute stroke: a cross-sectional fNIRS study. [PDF]

J Neuroeng Rehabil
Léger B, Auzou P, Fourdrinoy É, Sarrazin M, Celot S, Gay C, de Dieuleveult B, Cohen C, Özsancak C, Perrey S.   +9 more
europepmc   +1 more source