Results 101 to 110 of about 1,053,995 (363)

Cigarette Smoke Initiates Oxidative Stress-Induced Cellular Phenotypic Modulation Leading to Cerebral Aneurysm Pathogenesis. [PDF]

, 2018
OBJECTIVE: Cigarette smoke exposure (CSE) is a risk factor for cerebral aneurysm (CA) formation, but the molecular mechanisms are unclear. Although CSE is known to contribute to excess reactive oxygen species generation, the role of oxidative stress on ...
Ali, Muhammad S., Chalouhi, Nohra, Ding, Dale, Dumont, Aaron S., Hare, Joshua M., Hasan, David M., Jabbour, Pascal, Martinez Lege, Alejandra, Owens, Gary K, Pascale, Crissey L., Starke, Robert M., Thompson, John W., Toborek, Michal   +12 more
core   +2 more sources

The role of oxidative stress in cerebral aneurysm formation and rupture.

Current Neurovascular Research, 2013
Oxidative stress is known to contribute to the progression of cerebrovascular disease. Additionally, oxidative stress may be increased by, but also augment inflammation, a key contributor to cerebral aneurysm development and rupture. Oxidative stress can
R. Starke, N. Chalouhi, Muhammad S. Ali, P. Jabbour, S. Tjoumakaris, L. Gonzalez, R. Rosenwasser, W. Koch, A. Dumont   +8 more
semanticscholar   +1 more source

Impact of CYP2C19 Genotype Variants on PCSK9 Inhibitor Efficacy in Lipid‐Lowering Among Patients With Symptomatic Intracranial Atherosclerotic Stenosis

Lipids, EarlyView.
ABSTRACT Ischemic stroke is frequently associated with symptomatic intracranial atherosclerotic stenosis (sICAS), is a leading cause of global disability and mortality. Current guidelines recommend dual antiplatelet and intensive statin therapies. Proprotein convertase subtilisin 9/kexin type 9 (PCSK9) inhibitors have emerged as a potent lipid‐lowering
Chao Zhao, Nuan Wang, Di Shi, Hao Zhou, Dan Chen, Guofang Chen   +5 more
wiley   +1 more source

Training model for cerebral aneurysm clipping

Interdisciplinary Neurosurgery, 2017
Clipping of cerebral aneurysms is still an important skill in neurosurgery. We have made a training model for the clipping of cerebral aneurysms. The concepts for the model were 1: training model for beginners, 2: three dimensional manipulation using an ...
Hiroshi Tenjin, M.D., Ph.D., Yoshio Okano, B.S.   +1 more
doaj   +1 more source

Spontaneous subarachnoid haemorrhage due to coarctation of aorta and intraspinal collaterals : a rare presentation [PDF]

, 2012
The occurrence of spontaneous subarachnoid haemorrhage (SAH) in association with coarctation of thoracic aorta and absence of intracranial aneurysm is a rare association.
Devara, Anil K.V., Joseph, S., Uppu, S.C.   +2 more
core  

Fluid Structural Analysis of Human Cerebral Aneurysm Using Their Own Wall Mechanical Properties

Comput. Math. Methods Medicine, 2013
Computational Structural Dynamics (CSD) simulations, Computational Fluid Dynamics (CFD) simulation, and Fluid Structure Interaction (FSI) simulations were carried out in an anatomically realistic model of a saccular cerebral aneurysm with the objective ...
A. Valencia, Patricio A. Burdiles, M. Ignat, J. Mura, Eduardo Bravo, Rodrigo Rivera, J. Sordo   +6 more
semanticscholar   +1 more source

Circadian Immunity and Vascular Inflammation in Cardiovascular Disease Chronotherapy Windows: Time for a Re‐Assessment

Med Research, EarlyView.
ABSTRACT Circadian rhythms orchestrate cardiovascular physiology by regulating immune and inflammatory pathways. Disruption of these rhythms profoundly alters vascular homeostasis, thereby promoting the onset and progression of cardiovascular diseases (CVD).
Tian Zhang, Ge Zhang, Tian‐Ding Liu, Tianshu Gu, Fengyi Yu, Pengyuan Xu, Wunan Mi, Xuanjiang Zhao, Qian Guo, Honglin Zheng, Taiqi Zhao, Qiang Li, Di Lu, Mingxuan Duan, Chaoyang Yu, Ruhao Wu, Shiqian Zhang, Haonan Zhang, Zeyu Wang, Youyang Zheng, Yan Xiao, Zenglei Zhang, Ge Zhang   +22 more
wiley   +1 more source

Intracardiac Myxoma, Cerebral Aneurysms and Elevated Interleukin-6

Case Reports in Neurology, 2015
Cerebral aneurysms are well known to be associated with cardiac myxomas. The mechanism of cerebral aneurysm formation remains to be elucidated. Embolization of tumor particles in the vessel wall has been proposed as the likely mechanism for aneurysm ...
Nnadozie Ezerioha, Wuwei Feng
doaj   +1 more source

Cerebral hemodynamics on MR perfusion images before and after bypass surgery in patients with giant intracranial aneurysms [PDF]

, 2001
Preoperative assessment of the anatomy and dynamics of cerebral circulation for patients with giant intracranial aneurysm can improve both outcome prediction and therapeutic approach.
A. PIERALLINI, CARAMIA, Francesca, E. PASSACANTILLI, G. GUIDETTI, G. P. CANTORE, L. BOZZAO, L. M. FANTOZZI, P. PANTANO, SANTORO A.   +8 more
core  

Wall Orientation and Shear Stress in the Lattice Boltzmann Model

, 2012
The wall shear stress is a quantity of profound importance for clinical diagnosis of artery diseases. The lattice Boltzmann is an easily parallelizable numerical method of solving the flow problems, but it suffers from errors of the velocity field near ...
Aidun, Anor, Artoli, Axner, Berger, Bernsdorf, Bonert, Boussel, Bouzidi, Boyd, Carallo, Caro, Cebral, Cecchi, Chopard, Christ, Cosgrove, Dai, d’Humieres, Gohil, Harvey, He, He, Higuera, Jou, Krüger, Krüger, Ku, Ku, Luo, Maciej Matyka, Malek, McNamara, Meyerson, Milner, Nesbitt, Nickolls, Pantos, Papaioannou, Paszkowiak, Patankar, Peng, Peters, Pohl, Pontrelli, Quarteroni, Reneman, Shaaban, Stahl, Tse, Tölke, Xian, Zbigniew Koza, Łukasz Mirosław   +53 more
core   +1 more source