Results 121 to 130 of about 229,592 (307)

Methylglyoxal Accumulation is Associated with Brain Inflammation after Myocardial Infarction with Sex and Regional Differences

open access: yesAdvanced Science, EarlyView.
This study identifies that methylglyoxal may play an important role in heart‐brain interactions after myocardial infarction. Myocardial infarction leads to increased levels of methylglyoxal‐derived advanced glycation end‐products (MG‐H1) in the brain of mice, which is associated with loss of blood‐brain barrier integrity and neuroinflammation ...
Ramis Ileri, Xixi Guo, Erik J. Suuronen
wiley   +1 more source

FLAIR Hyperintense Vessel Sign of Both MCAs with Severe Heart Failure

open access: yesCase Reports in Neurological Medicine, 2016
Introduction. Fluid-attenuated inversion recovery hyperintense vessels (FHVs) can be seen in patients with occlusion or severe stenosis of the cerebral arteries. FHVs are known to reflect stagnant or slow blood flow within the cerebral artery.
Donghee Kim, Seung-Yul Lee, Kwon-Duk Seo
doaj   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

open access: yesAdvanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang   +6 more
wiley   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

open access: yesAdvanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale   +6 more
wiley   +1 more source

Capsaicin-Induced Ca2+ Influx and Constriction of the Middle Meningeal Artery [PDF]

open access: yes, 2014
Research in the past on transient receptor potential cation channel subfamily V member 1 (TRPV1) has been limited to mainly nervous tissue TRPV1 because of the channel’s role in pain perception.
Koide, Masayo   +5 more
core   +1 more source

Sono‐Mechanogenetics: Linking Ultrasound Physics With Cellular Mechanobiology

open access: yesAdvanced Science, EarlyView.
Sono‐mechanogenetics links ultrasound physics with cellular mechanotransduction to enable noninvasive control of engineered biological systems. Acoustic forces generate distinct deformation modes that activate intracellular signaling pathways, which can be coupled to synthetic gene circuits to regulate diverse cellular functions, including gene ...
Yunjia Qu   +4 more
wiley   +1 more source

Focal Spot, Summer/Fall 2006 [PDF]

open access: yes, 2006
https://digitalcommons.wustl.edu/focal_spot_archives/1103/thumbnail ...

core   +1 more source

Early Outcomes After Total Arch Replacement With Frozen Elephant Trunk in Elderly Patients With Acute Type A Aortic Dissection

open access: yesAGING MEDICINE, EarlyView.
Across seven centers (2015–2023), we studied 1634 ATAAD patients undergoing TAR+FET and, after propensity matching (n = 699), compared elderly (≥ 60) versus non‐elderly (< 60) outcomes. Elderly patients had higher 30‐day mortality and complications (log‐rank p = 0.002), supporting individualized hybrid strategies, organ‐protective perioperative care ...
Jiajun Liang   +11 more
wiley   +1 more source

Elevated Risk of Complications in Patients Receiving Dual Antithrombotic Therapy Undergoing Hepatectomy: A Single‐Center Audit of 749 Cases

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
This single‐center retrospective study evaluated perioperative outcomes after hepatectomy in 749 patients, including 140 receiving ATT, using propensity score matching to compare ATT and non‐ATT cohorts. Under standardized perioperative management, ATT did not increase major bleeding, transfusion, or severe morbidity overall; however, within the ATT ...
Haruki Mori   +9 more
wiley   +1 more source

Magnetic resonance angiography for cerebral arterial and venous visualization in dogs: a comparative study of time-of-flight, phase-contrast, and time-resolved imaging of contrast kinetics sequences

open access: yesFrontiers in Veterinary Science
This study aims to compare the effectiveness of three magnetic resonance angiography (MRA) sequences—Time-of-Flight (TOF), Phase-Contrast (PC), and Time-Resolved Imaging of Contrast Kinetics (TRICKS)—in visualizing cerebral arteries and veins in dogs ...
Sunghwa Hong   +6 more
doaj   +1 more source

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