Back Again to the Future: A New Era for Cerebroprotection
Cerebroprotection is a fresh framework for designing neurological therapy that targets glia and vascular cells, in addition to neurons. In the future, successful cerebroprotection will involve targeting all elements of the neurovascular unit. Preclinical trials must include functional outcomes, as well as lesion morphometry.
Patrick Lyden
wiley +1 more source
Assessing changes on large cerebral arteries in CADASIL: Preliminary insights from a case-control analysis. [PDF]
Lopez-Navarro ER +11 more
europepmc +1 more source
Alcohol and pregnenolone interaction on cerebral arteries through targeting of vascular smooth muscle Ca2+- and voltage-gated K+ channels of big conductance. [PDF]
North KC +4 more
europepmc +1 more source
Effect of Aging on Elastin Functionality in Human Cerebral Arteries
E. Fonck +6 more
semanticscholar +1 more source
Objective The objective of this study was to test if blood–brain barrier (BBB) disruption, detected using dynamic susceptibility contrast (DSC) imaging, would predict progression of white matter hyperintensities (WMHs) over the subsequent year in patients with chronic cerebrovascular disease. Methods The study included patients with a history of stroke
Richard Leigh +4 more
wiley +1 more source
Gene expression changes in human cerebral arteries following hemoglobin exposure: implications for vascular responses in SAH. [PDF]
Shafeeque CM +6 more
europepmc +1 more source
Timing of Peri‐Ictal MRI Abnormalities in Status Epilepticus – One Size Does Not Fit All
Objective We aimed to investigate timing of occurrence of peri‐ictal MRI abnormalities – a potential risk biomarker of status epilepticus‐related cerebral injury (t2). Methods This prospective study enrolled adult patients with status epilepticus and acute magnetic resonance imaging (MRI); patients with peri‐ictal MRI abnormalities underwent follow‐up ...
Pilar Bosque Varela +12 more
wiley +1 more source
Cerebrovascular longitudinal atlas: Changes in cerebral arteries in unruptured intracranial aneurysm patients followed with MRA. [PDF]
Chien A +8 more
europepmc +1 more source

