The middle cerebral artery (MCA) is one of the major paired intracranial arteries involved in the formation of the circle of Willis. MCA is the most complex of the intracranial arteries mainly because it supplies the cerebral neocortex, which has been ...
S. Matanov +3 more
doaj +1 more source
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa +7 more
wiley +1 more source
Separation of cortical arteries and veins in optical neurovascular imaging [PDF]
Separation of arteries and veins in the cerebral cortex is of significant importance in the studies of cortical hemodynamics, such as the changes of cerebral blood flow, perfusion or oxygen concentration in arteries and veins under different pathological
Linna Zhao +4 more
doaj +1 more source
P90: Kinetic Energy and Energy Loss in the Middle Cerebral Artery (MCA) of Heartmate II Patients [PDF]
Background In heart failure patients with continuous-flow left ventricular assist devices (CF-LVAD), arterial pulsatility in the brain is reduced and diastolic blood velocities (Vmin) are maintained.
Ji, Ruiping +15 more
core +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Fetal and Primitive Type of Circle of Willis with Unilateral Trifurcation of Internal Carotid Artery
Circle of Willis is a network of arteries in the base of the brain between the internal carotid artery and the vertebral artery to establish the collateral circulation between these two major arteries.
Sushma R.K. +2 more
doaj +1 more source
Multiple blood flow measurements before and after carotid artery stenting via phase-contrast magnetic resonance imaging: An observational study. [PDF]
After carotid artery stenting, the procurement of information about blood flow redistribution among brain-feeding arteries and its time trend is essential to understanding a patient's physiological background and to determine their care regimen. Cerebral
Hisashi Tanaka +7 more
doaj +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Relationship between oxygen supply and cerebral blood flow assessed by transcranial Doppler and near-infrared spectroscopy in healthy subjects during breath-holding [PDF]
Background Breath – holding (BH) is a suitable method for inducing cerebral vasomotor reactivity (VMR). The assessment of VMR is of clinical importance for the early detection of risk conditions and for the follow-up of disabled patients.
LIBONI W +10 more
core +1 more source
The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp +4 more
wiley +1 more source

