Results 51 to 60 of about 797,497 (225)

Stroke – correlations between clinical examination, imaging findings and microscopical aspects [PDF]

Romanian Journal of Neurology, 2015
Stroke is the most frequent cause of disability among the neurologic diseases of the adult. In the last two decades, the extraordinary development of brain imaging techniques allows the rapid recognition of normal, ischemic, infarction or hemorrhagic ...
Anca Hancu, Mariana Deacu, Madalina Bosoteanu   +2 more
doaj   +1 more source

CTE neuropathology alone is associated with dementia and cognitive symptoms

Alzheimer's &Dementia, Volume 22, Issue 1, January 2026.
Abstract INTRODUCTION This studyexamined the independent contribution of chronic traumatic encephalopathy (CTE) neuropathology to symptoms. METHODS The sample included 614 brain donors with (n = 366) and without (n = 248) autopsy‐confirmed CTE. Brain donors with other major neurodegenerative disease diagnoses were excluded.
Rachael M. Layden, Jenna R. Groh, Annalise E. Miner, Abigail Kidd, Sophia B. Nosek, Stephanie Gonzalez Gil, Bobak Abdolmohammadi, Steven Lenio, Christopher J. Nowinski, Yorghos Tripodis, Brett M. Martin, Joseph N. Palmisano, Brigid C. Dwyer, Douglas I. Katz, Lee E. Goldstein, Robert C. Cantu, Robert A. Stern, Thor D. Stein, Ann C. McKee, Daniel H. Daneshvar, Jesse Mez, Michael L. Alosco   +21 more
wiley   +1 more source

Effects of lithium ascorbate in middle-aged patients with stenosing atherosclerosis of brachiocephalic arteries

Фармакокинетика и Фармакодинамика, 2018
Resume. Lithium ascorbate is a highly digestible and low-toxic lithium salt. In stis study patients with stenosing arteriosclerosis of brachiocephalic arteries were under observation (n = 70, mean age 52 years, 50 % men).
E. A. Pepelyaev, V. A. Semenov, I. Yu. Torshin, O. A. Gromova   +3 more
doaj   +1 more source

Lobeglitazone improves glycaemic control as add‐on therapy to empagliflozin plus metformin in patients with type 2 diabetes mellitus: A double‐blind, randomised, placebo‐controlled trial

Diabetes, Obesity and Metabolism, Volume 28, Issue 1, Page 728-740, January 2026.
Abstract Aims This study aimed to evaluate the efficacy and safety of triple therapy with lobeglitazone 0.5 mg as an add‐on treatment compared with placebo in patients with type 2 diabetes mellitus (T2DM) inadequately controlled with metformin and empagliflozin.
Da Hea Seo, Kyung Wan Min, Ho Sang Sohn, Sang Yong Kim, In‐Kyung Jeong, Cheol‐Young Park, Kun‐Ho Yoon, So Hun Kim, Bong‐Soo Cha   +8 more
wiley   +1 more source

Sex-specific implications of inflammation in covert cerebral small vessel disease

BMC Neurology
Background The relationship between inflammation and covert cerebral small vessel disease (SVD) with regards to sex difference has received limited attention in research.
Bo-An Chen, Wei-Ju Lee, Lin-Chieh Meng, Yi-Chin Lin, Chih-Ping Chung, Fei-Yuan Hsiao, Liang-Kung Chen   +6 more
doaj   +1 more source

Intracranial carotid arteriosclerosis mediates the association between blood pressure and cerebral small vessel disease: the Rotterdam Study [PDF]

, 2022
Jesús D. Melgarejo, Meike W. Vernooij, M. Arfan Ikram, Z Y Zhang, D Bos   +4 more
openalex   +1 more source

Albiflorin‐Mediated MAP2K1 Targeting and HIF‐1 Signaling Inhibition Contribute to the Therapeutic Efficacy in Hyperuricemia‐Associated Cognitive Impairment

Human Mutation, Volume 2026, Issue 1, 2026.
This study investigated the therapeutic effects and mechanisms of Paeonia suffruticosa fruit pod extract (EMP) and its main component albiflorin (AF) on hyperuricemia‐associated cognitive impairment (HUA‐CI). A HUA‐CI mouse model was established, with cognitive function evaluated via Morris water maze.
Huimin Xiao, Xinwen Huang, Rui Yao, Jincai Liu, Linrui Duan, Siwang Wang, Jinming Gao, Minghua Ren   +7 more
wiley   +1 more source

A new score for predicting intracranial hemorrhage in patients using anticoagulant drugs

Frontiers in Neurology
ObjectivesThe use of anticoagulants in patients increases the risk of intracranial hemorrhage (ICH). Our aim was to identify factors associated with cerebral hemorrhage in patients using anticoagulants and to develop a predictive model that would provide
Fuxin Ma, Zhiwei Zeng, Jiana Chen, Chengfu Guan, Wenlin Xu, Chunhua Wang, Jinhua Zhang   +6 more
doaj   +1 more source

Primary stent retrieval for acute intracranial large artery occlusion due to atherosclerotic disease [PDF]

Journal of Stroke, 2016
Background and Purpose The goal of stent retriever–based thrombectomy is removal of embolic clots in patients with intracranial large artery occlusion. However, outcomes of stent retrieval may differ between acute arterial occlusions due to intracranial ...
Jin Soo Lee, Ji Man Hong, Kyu Sun Lee, Hong Il Suh, Jin Wook Choi, Sun Yong Kim   +5 more
doaj   +1 more source

Anticoagulant or Antithrombotic Therapy After Early Neurological Deterioration in Patients With Branch Atheromatous Disease Receiving Dual Antiplatelet Therapy

International Journal of Clinical Practice, Volume 2026, Issue 1, 2026.
Objective We evaluated the effectiveness and safety of adding tirofiban or argatroban after early neurological deterioration (END) in patients with branch atheromatous disease (BAD) receiving dual antiplatelet therapy and compared the outcomes with those of patients who continued dual antiplatelet therapy alone. Methods This retrospective study focused
Xuemin Zhong, Juan Yang, Ronghua Xu, Jian Wang, Nikhat Kaura   +4 more
wiley   +1 more source