Results 131 to 140 of about 782,046 (314)

Impaired endothelial function of the retinal vasculature in hypertensive patients [PDF]

open access: yes, 2004
<p><b>Background and Purpose:</b> Arterial hypertension constitutes a central factor in the pathogenesis of stroke. We examined endothelial function of the retinal vasculature as a model of the cerebral circulation.</p> <p ...
Delles, C.   +5 more
core   +1 more source

Regional cerebral perfusion and sympathetic activation during exercise in hypoxia and hypercapnia: preliminary insight into ‘Cushing's mechanism’

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend During handgrip exercise in hypoxia, brain perfusion is suboptimal and muscle sympathetic nerve activity is potentiated (left panel). During the exercise in hypercapnia, brain perfusion is supraoptimal and muscle sympathetic nerve activity is suppressed (right panel). These observations support the notion that Cushing's mechanism
Hsuan‐Yu Wan   +6 more
wiley   +1 more source

Dysfunctional cerebral autoregulation is associated with delirium in critically ill adults

open access: yesJournal of Cerebral Blood Flow and Metabolism, 2018
Delirium is common during critical illness and is associated with morbidity and mortality, but its pathophysiology is unknown. We tested whether dysfunctional cerebral autoregulation (CA) contributes to the development of delirium. Adult patients (n = 40)
Kevin F H Lee   +4 more
semanticscholar   +1 more source

Type 2 diabetes and depression via microvascular dysfunction, neurodegeneration, inflammation, advanced glycation end products (AGEs), and arterial stiffness

open access: yesDiabetes, Obesity and Metabolism, Volume 27, Issue 9, Page 4847-4858, September 2025.
Abstract Aims Type 2 diabetes increases the risk of depression, but the mechanisms underlying this association are incompletely understood. We investigated whether microvascular dysfunction, neurodegeneration, low‐grade inflammation, advanced glycation end products (AGEs) and arterial stiffness, pathologies that are more common in diabetes, explain, or
Indra L. M. Steens   +10 more
wiley   +1 more source

Blistering barnacles: Space physiology in The Adventures of Tintin

open access: yes
Experimental Physiology, EarlyView.
Jacob P. Hartmann   +4 more
wiley   +1 more source

Arterial stiffness moderates the link between NfL and cognition: The IGNITE study

open access: yesAlzheimer's &Dementia, Volume 21, Issue 8, August 2025.
Abstract INTRODUCTION Arterial stiffness (carotid‐femoral pulse wave velocity [cfPWV]) and plasma neurofilament light (NfL), markers of vascular and neuroaxonal aging, are linked to cognitive decline. Whether higher cfPWV amplifies the NfL–cognition relationship remains unclear.
Amani M. Norling   +22 more
wiley   +1 more source

Cerebral Small Vessel, But Not Large Vessel Disease, Is Associated With Impaired Cerebral Autoregulation During Cardiopulmonary Bypass: A Retrospective Cohort Study

open access: yesAnesthesia and Analgesia, 2018
BACKGROUND: Impaired cerebral blood flow (CBF) autoregulation during cardiopulmonary bypass (CPB) is associated with stroke and other adverse outcomes. Large and small arterial stenosis is prevalent in patients undergoing cardiac surgery.
Yohei Nomura   +8 more
semanticscholar   +1 more source

Risk factors associated with progression from pre‐eclampsia to eclampsia: A prospective cohort study and population‐wide data analysis

open access: yesActa Obstetricia et Gynecologica Scandinavica, Volume 104, Issue 8, Page 1487-1495, August 2025.
Younger maternal age and lower socioeconomic status emerged as key risk factors for progression from pre‐eclampsia to eclampsia in two low‐ and middle‐income countries (Uganda and Ecuador), challenging the traditional focus on disease severity alone. This suggests a need to broaden risk assessment criteria.
Annettee Nakimuli   +9 more
wiley   +1 more source

Compromised Dynamic Cerebral Autoregulation in Patients With Depression

open access: yesFrontiers in Psychiatry, 2019
Background: Patients with depression tend to have various comorbid neurological symptoms, but the mechanisms remain unclear. The purpose of this study was to analyze the characteristics of dynamic cerebral autoregulation in depressed patients.Methods ...
Ming-Ya Luo   +9 more
doaj   +1 more source

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