Results 141 to 150 of about 775,260 (336)

Vascular health and exercise in females throughout the lifespan: Exploring puberty, pregnancy and menopause

open access: yesExperimental Physiology, EarlyView.
Abstract This narrative review highlights the impact of exercise on vascular health in females over the lifespan with an emphasis on puberty, pregnancy and menopause. These events encompass substantial changes in sex hormone levels, particularly oestrogens and progesterone.
Kathleen B. Miller   +2 more
wiley   +1 more source

Phase synchronization in cerebral hemodynamics [PDF]

open access: yesarXiv, 2004
A healthy human brain is perfused with blood flowing laminarly through cerebral vessels, providing brain tissue with substrates such as oxygen and glucose. Under normal conditions, cerebral blood flow is controlled by autoregulation as well as metabolic, chemical and neurogenic regulation.
arxiv  

Effects of noradrenaline and phenylephrine on cerebral oxygen saturation during cardiopulmonary bypass in cardiac surgery

open access: yesExperimental Physiology, EarlyView.
Abstract Cardiopulmonary bypass (CPB) in cardiac surgery is associated with a high risk of postoperative neurological complications. Perioperative use of vasopressors is common to counteract arterial hypotension in this setting. However, use of α‐agonist vasopressors has been associated with cerebral desaturations.
Edouard Marques   +7 more
wiley   +1 more source

Dysfunctional cerebral autoregulation is associated with delirium in critically ill adults

open access: yesJournal of Cerebral Blood Flow and Metabolism, 2018
Delirium is common during critical illness and is associated with morbidity and mortality, but its pathophysiology is unknown. We tested whether dysfunctional cerebral autoregulation (CA) contributes to the development of delirium. Adult patients (n = 40)
Kevin F H Lee   +4 more
semanticscholar   +1 more source

Cerebral Small Vessel, But Not Large Vessel Disease, Is Associated With Impaired Cerebral Autoregulation During Cardiopulmonary Bypass: A Retrospective Cohort Study

open access: yesAnesthesia and Analgesia, 2018
BACKGROUND: Impaired cerebral blood flow (CBF) autoregulation during cardiopulmonary bypass (CPB) is associated with stroke and other adverse outcomes. Large and small arterial stenosis is prevalent in patients undergoing cardiac surgery.
Yohei Nomura   +8 more
semanticscholar   +1 more source

Serum Levels of Brain-Derived Neurotrophic Factor and Insulin-Like Growth Factor 1 Are Associated With Autonomic Dysfunction and Impaired Cerebral Autoregulation in Patients With Epilepsy

open access: yesFrontiers in Neurology, 2018
Background: Brain-derived neurotrophic factor (BDNF) and insulin-like growth factor 1 (IGF-1) may regulate the autonomic nervous system (ANS) in epilepsy.
Shu-Fang Chen   +12 more
doaj   +1 more source

A simple model of cerebral blood flow dependence on arterial blood pressure [PDF]

open access: yesarXiv, 2011
It is shown that the dependence of the cerebral blood flow (CBF) on mean arterial blood pressure (MABP) can be described with a simple model having the following assumptions. Below certain MABP (denoted as MABP1) there are no autoregulatory or feedback mechanisms influencing CBF.
arxiv  

Modelling the Role of Nitric Oxide in Cerebral Autoregulation [PDF]

open access: yesarXiv, 2015
Malfunction of the system which regulates the bloodflow in the brain is a major cause of stroke and dementia, costing many lives and many billions of pounds each year in the UK alone. This regulatory system, known as cerebral autoregulation, has been the subject of much experimental and mathematical investigation yet our understanding of it is still ...
arxiv  

Transcriptional leakage versus noise: A simple mechanism of conversion between binary and graded response in autoregulated genes [PDF]

open access: yes, 2014
We study the response of an autoregulated gene to a range of concentrations of signal molecules. We show that transcriptional leakage and noise due to translational bursting have the opposite effects. In a positively autoregulated gene, increasing the noise converts the response from graded to binary, while increasing the leakage converts the response ...
arxiv   +1 more source

Worsening of cerebral hyperemia by the administration of terlipressin in acute liver failure with severe hepatic encephalopathy [PDF]

open access: yes, 2004
There is increasing evidence that terlipressin is useful in patients with cirrhosis and hepatorenal syndrome, but there are no data of its use in patients with acute liver failure (ALF) in whom hepatorenal syndrome is common.
Davies, N.A.   +6 more
core  

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