Effect of sevoflurane on systemic and cerebral circulation, cerebral autoregulation and CO2 reactivity [PDF]
, 2019 Background: Sevoflurane is one of the most frequently used inhaled anesthetics for general anesthesia. Previously it has been reported that at clinically used doses of sevoflurane, cerebral vasoreactivity is maintained.
Fülesdi, Béla +6 more
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The Cells of the Vasculature: Advances in the Regulation of Vascular Tone in the Brain and Periphery
Basic &Clinical Pharmacology &Toxicology, Volume 136, Issue 5, May 2025.ABSTRACT The vasculature is a complex tissue in which multiple cell types coordinate the regulation of tissue perfusion in response to hemodynamic and biochemical signals. Advances in this field are continuing to deepen our understanding of the relative importance of these cell types through the body.
Luke S. Dunaway +3 more
wiley +1 more source
The Pathobiology of Cerebrovascular Lesions in CADASIL Small Vessel Disease
Basic &Clinical Pharmacology &Toxicology, Volume 136, Issue 5, May 2025.ABSTRACT Cerebral small vessel disease (cSVD) is a significant global health issue, accounting for approximately 25% of ischemic strokes and 20% of all dementia cases. CADASIL, the most common monogenic form of cSVD, is caused by stereotyped mutations in the NOTCH3 receptor that alter the number of cysteine residues in its extracellular domain ...
Anne Joutel
wiley +1 more source
Cerebral Autoregulation in Hypertension and Ischemic Stroke: A Mini Review.
Journal of pharmaceutical sciences and experimental pharmacology, 2017 Aging and chronic hypertension are associated with dysfunction in vascular smooth muscle, endothelial cells, and neurovascular coupling. These dysfunctions induce impaired myogenic response and cerebral autoregulation, which diminish the protection of ...
S. Shekhar +4 more
semanticscholar +1 more source
Pediatric Transplantation, Volume 29, Issue 3, May 2025.We analyzed a retrospective, observational cohort of 51 patients with pediatric acute liver failure with severe hepatic encephalopathy (grade III‐IV), admitted between 1993 and 2023. The survival rate in patients with present PR was higher compared to patients with absent PR (70% and 29%, respectively).
Kirsten J. Schouwstra +6 more
wiley +1 more source
Autoregulation of cerebral blood flow: influence of the arterial blood pressure on the blood flow through the cerebral cortex. [PDF]
, 1966 A. M. Harper
openalex +1 more source
Temporal Course of Dynamic Cerebral Autoregulation in Patients With Intracerebral Hemorrhage
Stroke, 2016 Background and Purpose— Cerebral autoregulation is crucial in patients with intracerebral hemorrhage. Dynamic cerebral autoregulation is probably altered in acute intracerebral hemorrhage; however, the temporal course of dynamic cerebral autoregulation ...
Hongyin Ma +5 more
semanticscholar +1 more source
Extended model of impaired cerebral autoregulation in preterm infants: Heuristic feedback control
Mathematical Biosciences and Engineering, 2019 Cerebral autoregulation is the ability to keep almost constant cerebral blood flow (CBF) for some range of changing the mean arterial pressure (MAP). In preterm infants, this range is usually very small, even absent, and a passive (linear) dependence of ...
Nikolai D. Botkin +4 more
doaj +1 more source
A simple deep breathing test reveals altered cerebral autoregulation in type 2 diabetic patients [PDF]
, 2018 Aims/hypothesis: Patients with diabetes mellitus have an increased risk of stroke and other cerebrovascular complications. The purpose of this study was to evaluate the autoregulation of cerebral blood flow in diabetic patients using a simple method that
Brown, C. +4 more
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