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A multiscale model of cerebral autoregulation

Medical Engineering & Physics, 2021
The mechanism of cerebral autoregulation ensures a continuous and sufficient blood supply to the brain to maintain normal function in the presence of changes in blood pressure. Impaired cerebral autoregulation is implicated in a range of brain diseases.
Zheng Tong   +2 more
openaire   +3 more sources

Personalized Blood Pressure Management During Cardiac Surgery With Cerebral Autoregulation Monitoring: A Randomized Trial.

Seminars in Thoracic and Cardiovascular Surgery, 2020
The purpose of this study was to determine if setting mean arterial pressure (MAP) targets during cardiopulmonary bypass (CPB) based on individualized cerebral autoregulation data reduces the frequency of neurological complications compared with usual ...
C. Hogue   +8 more
semanticscholar   +1 more source

Monitoring of Cerebral Autoregulation

Neurocritical Care, 2014
Pressure autoregulation is an important hemodynamic mechanism that protects the brain against inappropriate fluctuations in cerebral blood flow in the face of changing cerebral perfusion pressure (CPP). Static autoregulation represents how far cerebrovascular resistance changes when CPP varies, and dynamic autoregulation represents how fast these ...
Czosnyka M.   +34 more
openaire   +3 more sources

Cerebral autoregulation and anesthesia

Current Opinion in Anaesthesiology, 2009
This review will examine the recent literature on anesthesia and monitoring techniques in relation to cerebral autoregulation. We will discuss the effect of physiologic and pharmacological factors on cerebral autoregulation alongside its clinical relevance with the help of new evidence.Intravenous anesthesia, such as combination of propofol and ...
Arthur M. Lam, Armagan Dagal
openaire   +3 more sources

Cerebral autoregulation and ageing

Journal of Clinical Neuroscience, 2005
Little is known about the effects of ageing on cerebral autoregulation (CA). To examine the relationship between age and CA in adults, we conducted a prospective study using a non-invasive protocol without external stimuli. We studied 32 subjects, aged 23-68 years. They were assigned to a young group (28+/-5 years) and an old group (54+/-8 years).
Yam, A T   +6 more
openaire   +4 more sources

Assessment of cerebral pressure autoregulation

Current Opinion in Anaesthesiology, 2002
Cerebral pressure autoregulation, a sensitive homeostatic mechanism important for the control of cerebral blood flow, is impaired by disease pathology and some drugs commonly used during anaesthesia. Therefore, the assessment of cerebral pressure autoregulation can help optimize cerebral blood flow in patients who have suffered neurological insults. In
RASULO, Francesco Antonio   +2 more
openaire   +4 more sources

Cerebral Autoregulation in Orthostatic Intolerance

Annals of the New York Academy of Sciences, 2001
Abstract: Many of the primary symptoms of orthostatic intolerance (fatigue, diminished concentration) as well as some of the premonitory symptoms of neurally mediated syncope (NMS) are thought to be due to cerebral hypoperfusion. Transcranial Doppler measurements of middle cerebral artery blood velocity (CBV) is at present the only technique for ...
Reuben Stein   +2 more
openaire   +3 more sources

Cerebral Autoregulation and Syncope

Progress in Cardiovascular Diseases, 2007
Whatever the pathogenesis of syncope is, the ultimate common cause leading to loss of consciousness is insufficient cerebral perfusion with a critical reduction of blood flow to the reticular activating system. Brain circulation has an autoregulation system that keeps cerebral blood flow constant over a wide range of systemic blood pressures. Normally,
openaire   +3 more sources

Cerebral autoregulation

Acta Neuropsychiatrica, 2008
No abstract available.
openaire   +2 more sources

Phase dynamics in cerebral autoregulation

American Journal of Physiology-Heart and Circulatory Physiology, 2005
Complex continuous wavelet transforms are used to study the dynamics of instantaneous phase difference Δφ between the fluctuations of arterial blood pressure (ABP) and cerebral blood flow velocity (CBFV) in a middle cerebral artery. For healthy individuals, this phase difference changes slowly over time and has an almost uniform distribution for the ...
Dariusz Latka   +5 more
openaire   +2 more sources

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