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The frequency response of cerebral autoregulation
Journal of Applied Physiology, 2013The frequency-response of pressure autoregulation is not well delineated; therefore, the optimal frequency of arterial blood pressure (ABP) modulation for measuring autoregulation is unknown. We hypothesized that cerebrovascular autoregulation is band-limited and delineated by a cutoff frequency for which ABP variations induce cerebrovascular ...
Peter Smielewski +9 more
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2017
The human brain is by far the most expensive organ in terms of energy expenditure in the whole body, characterized by high metabolic activity with fine regulatory mechanisms, defined as cerebral autoregulation, to ensure adequate energy substrates supply in register with brain activity.
R. Liu, S.-H. Yang
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The human brain is by far the most expensive organ in terms of energy expenditure in the whole body, characterized by high metabolic activity with fine regulatory mechanisms, defined as cerebral autoregulation, to ensure adequate energy substrates supply in register with brain activity.
R. Liu, S.-H. Yang
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Clinical Significance of Cerebral Autoregulation
2002Disturbed cerebral autoregulation is believed to be associated with an unfavourable outcome following head injury. Previously, using ICP monitoring and transcranial Doppler ultrasonography, we investigated whether cerebral response to spontaneous variations in arterial pressure (ABP) or cerebral perfusion pressure (CPP) provide reliable information on ...
Stefan K. Piechnik +3 more
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Journal of Neurotrauma, 2019
Traumatic brain injury (TBI) contributes to morbidity in children, and boys are disproportionately represented. Cerebral blood flow (CBF) is reduced and autoregulation is impaired after TBI, contributing to poor outcome. Cerebral perfusion pressure (CPP)
Hugh Hekierski +3 more
semanticscholar +1 more source
Traumatic brain injury (TBI) contributes to morbidity in children, and boys are disproportionately represented. Cerebral blood flow (CBF) is reduced and autoregulation is impaired after TBI, contributing to poor outcome. Cerebral perfusion pressure (CPP)
Hugh Hekierski +3 more
semanticscholar +1 more source
Influence of nitroprusside on cerebral pressure autoregulation
Neurosurgery, 1979The authors studied 10 cats to assess the question of abolition of cerebral autoregulation attendant on the use of nitroprusside for hypotensive anesthesia. After the establishment of stable base line parameters, a continuous infusion of sodium nitroprusside was begun in a dose sufficient to maintain a mean systemic arterial pressure of 65 mm Hg ...
Heiden Js +5 more
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Cerebrovascular and brain metabolism reviews, 1990
Autoregulation of blood flow denotes the intrinsic ability of an organ or a vascular bed to maintain a constant perfusion in the face of blood pressure changes. Alternatively, autoregulation can be defined in terms of vascular resistance changes or simply arteriolar caliber changes as blood pressure or perfusion pressure varies.
Paulson, O B +2 more
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Autoregulation of blood flow denotes the intrinsic ability of an organ or a vascular bed to maintain a constant perfusion in the face of blood pressure changes. Alternatively, autoregulation can be defined in terms of vascular resistance changes or simply arteriolar caliber changes as blood pressure or perfusion pressure varies.
Paulson, O B +2 more
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Critical Care Medicine, 2018
Objectives: Pressure reactivity index and oxygen reactivity index are used to assess cerebral autoregulation after acute brain injury. The value of autoregulation indices in the prediction of delayed cerebral ischemia and outcome in patients with ...
M. Gaasch +8 more
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Objectives: Pressure reactivity index and oxygen reactivity index are used to assess cerebral autoregulation after acute brain injury. The value of autoregulation indices in the prediction of delayed cerebral ischemia and outcome in patients with ...
M. Gaasch +8 more
semanticscholar +1 more source
Impaired cerebral autoregulation: measurement and application to stroke
Journal of Neurology Neurosurgery & Psychiatry, 2017Cerebral autoregulation (CA) is a protective mechanism that maintains cerebral blood flow at a relatively constant level despite fluctuations of cerebral perfusion pressure or arterial blood pressure.
L. Xiong +11 more
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Quantification of dynamic cerebral autoregulation: welcome to the jungle!
Clinical Autonomic Research, 2023Patrice Brassard +4 more
semanticscholar +1 more source
Nonstationarity of dynamic cerebral autoregulation
Medical Engineering & Physics, 2014Dynamic cerebral autoregulation (dCA), the transient response of cerebral blood flow (CBF) to rapid changes in arterial blood pressure (BP), is usually quantified by parameters extracted from time- or frequency-domain analysis. Reproducibility studies of dCA parameters and consideration of the physiological determinants of the dynamic BP-CBF ...
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