Results 101 to 110 of about 5,618,586 (305)

The effects of chronic trans-resveratrol supplementation on aspects of cognitive function, mood, sleep, health and cerebral blood flow in healthy, young humans [PDF]

, 2015
Single doses of resveratrol have previously been shown to increase cerebral blood flow (CBF) with no clear effect on cognitive function or mood in healthy adults.
Haskell, Crystal, Kennedy, David O., Kennedy, David, Reay, Jonathon, Wightman, Emma L., Reay, Jonathon L., Zhang, Wei, Dew, Tristan, Dew, Tristan P., Wightman, Emma, Haskell-Ramsay, Crystal F., Williamson, Gary   +11 more
core   +1 more source

Diffuse MRI Edema Predicts Relapse in Cerebral Amyloid Angiopathy–Related Inflammation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To identify MRI predictors of relapse and quantify relapse and mortality risk in cerebral amyloid angiopathy–related inflammation (CAA‐RI). A secondary objective was to assess the association between mycophenolate mofetil use and relapse risk. Methods We performed a retrospective cohort study of 36 patients with CAA‐RI treated at the
G. Abbas Kharal, Gowtham Yerneni, Kim J. Griffin, Nicolas Thompson, Ken Uchino, Irene Katzan, Dolora Wisco, Abeer Farrag, Jayashree Sundarajan, Andrew Russman, M. Shazam Hussain   +10 more
wiley   +1 more source

The relationship between thyroid function and cerebral blood flow in mild cognitive impairment and Alzheimer's disease.

PLoS ONE, 2019
The thyroid hormones have been reported to be associated with cognitive decline and Alzheimer's disease. The relationship between thyroid function within the normal range and cerebral blood flow in Alzheimer's disease patients has been shown in a recent ...
Shohei Nomoto, Ryuta Kinno, Hirotaka Ochiai, Satomi Kubota, Yukiko Mori, Akinori Futamura, Azusa Sugimoto, Takeshi Kuroda, Satoshi Yano, Hidetomo Murakami, Takako Shirasawa, Takahiko Yoshimoto, Akira Minoura, Akatsuki Kokaze, Kenjiro Ono   +14 more
doaj   +1 more source

Enhanced Ultrasound Transmission Through Aberration Layers Using Space‐Coiling Acoustic Metamaterials

Advanced Engineering Materials, EarlyView.
Enhancing ultrasound transmission through an aberration layer exhibiting mismatched impedance with the surrounding medium possesses great implications in imaging and treatment. In this study, we show that a space‐coiling acoustic metamaterial with judiciously tailored structural profile can help improve impedance matching.
Maral Ghanami, Hengzhe Ren, Erqian Dong, Ashkan Ghanbarzadeh‐Dagheyan, Chen Shen   +4 more
wiley   +1 more source

Perfusion by Arterial Spin labelling following Single dose Tadalafil In Small vessel disease (PASTIS): study protocol for a randomised controlled trial

Trials, 2017
Background Cerebral small vessel disease is a common cause of vascular cognitive impairment in older people, with no licensed treatment. Cerebral blood flow is reduced in small vessel disease.
Mathilde M. H. Pauls, Natasha Clarke, Sarah Trippier, Shai Betteridge, Franklyn A. Howe, Usman Khan, Christina Kruuse, Jeremy B. Madigan, Barry Moynihan, Anthony C. Pereira, Debbie Rolfe, Egill Rostrup, Caroline E. Haig, Thomas R. Barrick, Jeremy D. Isaacs, Atticus H. Hainsworth   +15 more
doaj   +1 more source

Blockade of the MEK/ERK pathway with a raf inhibitor prevents activation of pro-inflammatory mediators in cerebral arteries and reduction in cerebral blood flow after subarachnoid hemorrhage in a rat model.

, 2011
Cerebral ischemia that develops after subarachnoid hemorrhage (SAH) carries high morbidity and mortality. Inflammatory mediators are involved in the development of cerebral ischemia through activation of the mitogen-activated protein kinase pathway.
Chen, Qingwen, Edvinsson, Lars, Maddahi, Aida,, Edvinsson, Lars,, Maddahi, Aida, Ansar, Saema,, Chen, Qingwen,, Lund University., Ansar, Saema   +8 more
core   +1 more source

Engineered Microvascular Model of the Blood–Brain–Tumor Barrier Reveals Endothelial Remodeling in Diffuse Midline Glioma

Advanced Healthcare Materials, EarlyView.
We developed a patient‐derived, functional microfluidic model of the diffuse midline glioma (DMG) blood–brain–tumor barrier (BBTB) comprised of endothelial cells, astrocytes, pericytes, and tumor cells. The system forms perfusable microvasculature, reveals the BBTB retains vascular integrity, identifies DMG‐specific transcriptomic changes distinct from
Kimberly R. Bennett, Yann S. Vanrobaeys, Tessy Teboh, Zakiya Smith, Anderson Scott, Cynthia Hajal, Paula T. Hammond, Joelle P. Straehla   +7 more
wiley   +1 more source

Worsening of cerebral hyperemia by the administration of terlipressin in acute liver failure with severe hepatic encephalopathy [PDF]

, 2004
There is increasing evidence that terlipressin is useful in patients with cirrhosis and hepatorenal syndrome, but there are no data of its use in patients with acute liver failure (ALF) in whom hepatorenal syndrome is common.
Jalan, R., Hayes, P.C., Mookerjee, R.P., Shawcross, D.L., Williams, R., Lee, A., Davies, N.A.   +6 more
core  

Basal cerebral blood volume during the poststimulation undershoot in BOLD MRI of the human brain.

, 2010
One of the characteristics of the blood oxygenation level-dependent (BOLD) magnetic resonance imaging (MRI) response to functional challenges of the brain is the poststimulation undershoot, which has been suggested to originate from a delayed recovery ...
Merboldt, K., Frahm, Jens, Schuetze, Gunther, Helms, Gunther, Gunther Helms, Jens Frahm, Klaus Dietmar Merboldt, Helms, Gunther,, Schuetze, G., Helms, G., Merboldt, Klaus-Dietmar, Peter Dechent, Frahm, J., Dechent, Peter, Merboldt, K. D., Gunther Schütze, Dechent, P., Lund University.   +17 more
core   +1 more source

Mitochondria‐Targeted Nanotherapies in Aging Neurodegenerative Disorders: Emerging Prospects and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave, Ashish B. Jadhav, Nitin B. Waghamode, Shubham Khot, Rajiya Khan, Ravi Hole, Shankar M. Dhobale, Manoj Aswar, Keshav Raj Paudel   +8 more
wiley   +1 more source