Results 91 to 100 of about 5,618,586 (305)

An automated multiscale ensemble simulation approach for vascular blood flow [PDF]

, 2015
Cerebrovascular diseases such as brain aneurysms are a primary cause of adult disability. The flow dynamics in brain arteries, both during periods of rest and increased activity, are known to be a major factor in the risk of aneurysm formation and ...
Itani, MA, Hetherington, J, Chandrashekar, H, Hetherington, James, Schiller, UD, Chandrashekar, Hoskote, Groen, D, Groen, Derek, Schmieschek, Sebastian, Schiller, Ulf D., Itani, Mohamed A., Coveney, Peter V., Bernabeu, MO, Robertson, F, Schmieschek, S, Coveney, PV, Bernabeu, Miguel O.; id_orcid, Robertson, Fergus, Bernabeu, Miguel O., Hetherington, James P.J., Bernabéu, Miguel Óscar, Groen, Derek J., Robertson, Fergus J., Chandrashekar, Hoskote S.   +23 more
core   +1 more source

Modern Management of Asymptomatic Carotid Stenosis: A Meta‐Analysis of CREST‐2, SPACE‐2, and ECST‐2

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Recent randomized trials (CREST‐2, SPACE‐2, and ECST‐2) have compared carotid revascularization (carotid endarterectomy [CEA] or carotid artery stenting [CAS]) plus contemporary medical therapy (CMT) versus CMT alone in asymptomatic carotid stenosis.
Aasim Ali, Waqar Ahmed Cheema, Fiza Nisar, Muhammad Shamoon, Sameen Sarfaraz, Ahmad Butt, Muhammad Abdullah Ali, Armaghana Abdullah, Muhammad Asad Shabbir, Muhammad Talha, Hammad Azam, Aimen Anwaar Pannun, Usama Saleem, Anousha Tanveer, Mukesh Sharma   +14 more
wiley   +1 more source

[Cerebral blood flow in infants: comparison of carotid blood flow and cerebral blood velocity].

No to hattatsu = Brain and development, 1990
Carotid blood was measured with a ultrasonic volume flow meter in 38 infants. The carotid blood flow was 1.50 +/- 0.55 ml/sec. At the same time peak systolic flow velocity, mean blood velocity, end diastolic velocity, pulsatility index (PI) and resistance index (RI) in the middle and anterior cerebral arteries were measured by duplex Doppler scanning ...
Tatsuno, Masaru, Furusho, Junichi, Ohno, Hiromi, Okuyama, Kazuo   +3 more
openaire   +2 more sources

Progressive Parkinsonism in PPP2R5D‐Related Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT PPP2R5D‐related neurodevelopmental disorder (Houge–Janssens syndrome type 1) is a rare autosomal dominant condition characterized by macrocephaly, intellectual disability, and epilepsy. Progressive parkinsonism is an emerging adult phenotype that neurologists should be aware of since timely genetic diagnosis opens the door to disease‐modifying
Katerina Bernardi, Enrique Gonzalez Saez‐Diez, Joshua Rong, Beril Ay, Shabbir Merchant, Kathryn Yang, Darius Ebrahimi‐Fakhari   +6 more
wiley   +1 more source

Combined pulse wave velocity and triglyceride–glucose index to discriminate large-artery atherosclerosis from small-vessel occlusion in acute ischaemic stroke: a single-centre retrospective study

Frontiers in Neurology
ObjectiveEarly etiologic discrimination between large-artery atherosclerosis (LAA) and small-vessel occlusion (SVO) is clinically relevant when advanced imaging is unavailable or delayed.
Zhe Li, Ran Hui, Xiaoyun Guo, Qinmao Fang, Heping Deng   +4 more
doaj   +1 more source

Postishemic Cerebral Function and Blood Flow

Общая реаниматология, 2005
The impact of massive blood loss on cerebral blood flow-function relationships was studied in rats in the postis-chemic period. Anxiety was examined in the raised cross-shaped labyrinth.
V. V. Aleksandrin, V. L. Kozhura, I. S. Novoderzhkina, Ye. Yu. Parshina   +3 more
doaj   +1 more source

Assessing blood flow control through a bootstrap method [PDF]

, 2004
In order to assess blood flow control, the relationship between blood pressure and blood flow can be modeled by linear filters. We present a bootstrap method, which allows the statistical analysis of an index of blood flow control that is obtained from ...
Lopes, J.M.A., Villar Marinatto, M.N., J.M.A. Lopes (7580195), Simpson, D.M., E.G. Ramos (7580192), J. Nadal (5404268), Evans, D.H., D.H. Evans (7580198), Nadal, J., Panerai, R.B., Ramos, E.G., M. Villar (2433340), D.M. Simpson (7580186), R.B. Panerai (7580189)   +13 more
core   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Assessment of control and performance of biomedical systems [PDF]

, 2010
Introduction: In biomedical systems repeated measurements are often collected, thus presenting a statistical challenge due to high temporal correlation. This research investigates the potential utility of two distinct statistical methodologies in their ...
Harris, Katie
core   +4 more sources

Arterial Spin‐Labeling MRI at the Cortical‐CSF Interface: A Novel Biomarker in Alzheimer Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background/Objective Arterial spin‐labeling (ASL) MRI can measure perfusion signal adjacent to CSF spaces and may provide information regarding CSF‐adjacent water transport physiology. We developed an automated pipeline to extract cortical‐CSF interface (IF) perfusion for comparison between Alzheimer disease (AD) and cognitively normal ...
Mona Asghariahmadabad, Pouya Metanat, Michael Thomas, Luke W. Bonham, Tyson Lam, Mehmet Kurt, Hong Nguyen, Tara Ellingson, Mauro Zucchelli, Stefano Casagranda, Quin Lu, Andreas M. Rauschecker, Leo Sugrue, Luis E. Savastano, Christopher P. Hess, Kamalini Ranasinghe, S. Andrew Josephson, Bruce L. Miller, Jennifer S. Yokoyama, Gil D. Rabinovici, Peter A. Ljubenkov, Lawren VandeVrede, Kambiz Nael   +22 more
wiley   +1 more source