Results 71 to 80 of about 5,618,586 (305)

Detection of impaired cerebral autoregulation improves by increasing arterial blood pressure variability

, 2013
Although the assessment of dynamic cerebral autoregulation (CA) based on measurements of spontaneous fluctuations in arterial blood pressure (ABP) and cerebral blood flow (CBF) is a convenient and much used method, there remains uncertainty about its ...
Simpson, David M., Bush, Glen, Allen, Robert, Birch, Anthony A., Potter, John F., Panerai, Ronney B., Fan, Lingke, Katsogridakis, Emmanuel   +7 more
core   +1 more source

MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru, Akansha Chandrasekar, Kyla Blasingame, Jonathan Rosen, Jesse M. Levine, Karla Salazar, Madhuri Chilakapati, Rod Foroozan, Victoria Hardwick, Jonathan M. Yarimi, Nikita Shukla, Timothy E. Lotze, Kristen S. Fisher, Alexander J. Sandweiss   +13 more
wiley   +1 more source

Quantitative analysis of systemic perfusion and cerebral blood flow in the modeling of aging and orthostatic hypotension

Frontiers in Physiology
Introduction: Orthostatic hypotension (OH) is common among the older population. The mechanism hypothesized by OH as a risk factor for cognitive decline and dementia is repeated transient cerebral blood flow deficiency.
Heming Cheng, Jifeng Dai, Gen Li, Dongfang Ding, Jianyun Li, Ke Zhang, Liuchuang Wei, Jie Hou   +7 more
doaj   +1 more source

Increasing cerebral blood flow improves cognition into late stages in Alzheimer's disease mice

, 2020
Alzheimer's disease is associated with a 20-30% reduction in cerebral blood flow. In the APP/PS1 mouse model of Alzheimer's disease, inhibiting neutrophil adhesion using an antibody against the neutrophil specific protein Ly6G was recently shown to drive
Bracko, Oliver, Swallow, Madisen, Haft-Javaherian, Mohammad, Ali, Muhammad, Schaffer, Chris B., Njiru, Brendah N.   +5 more
core   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source

Cerebral blood flow in Alzheimer’s disease

Vascular Health and Risk Management, 2012
Alex E Roher,1 Josef P Debbins,2 Michael Malek-Ahmadi,3 Kewei Chen,4 James G Pipe,2 Sharmeen Maze,2 Christine Belden,3 Chera L Maarouf,1 Pradeep Thiyyagura,4 Hua Mo,4 Jesse M Hunter,1 Tyler A Kokjohn,1,5 Douglas G Walker,6 Jane C Kruchowsky,6 Marek ...
Roher AE, Debbins JP, Malek-Ahmadi M, Chen K, Pipe JG, Maze S, Belden C, Maarouf CL, Thiyyagura P, Mo H, Hunter JM, Kokjohn TA, Walker DG, Kruchowsky JC, Belohlavek M, Sabbagh MN, Beach TG   +16 more
doaj  

The pathogenesis of microglia in traumatic brain injury

Chinese Journal of Contemporary Neurology and Neurosurgery
The mechanism of secondary injury after tramatic brain injury (TBI) is related to inflammation reation, oxidative stress, inflammasome, and so on, and microglia are closely related to it. Microglia, as macrophage in the nervous system, participate in the
HAN Jia-liang, ZHANG Guo-bin
doaj   +1 more source

Multiple blood flow measurements before and after carotid artery stenting via phase-contrast magnetic resonance imaging: An observational study. [PDF]

PLoS ONE, 2018
After carotid artery stenting, the procurement of information about blood flow redistribution among brain-feeding arteries and its time trend is essential to understanding a patient's physiological background and to determine their care regimen. Cerebral
Hisashi Tanaka, Yoshiyuki Watanabe, Hajime Nakamura, Hiroto Takahashi, Atsuko Arisawa, Takuya Fujiwara, Chisato Matsuo, Noriyuki Tomiyama   +7 more
doaj   +1 more source

Respiratory influence on cerebral blood flow and blood volume : a 4D flow MRI study

Variations in cerebral blood flow and blood volume interact with intracranial pressure and cerebrospinal fluid dynamics, all of which play a crucial role in brain homeostasis. A key physiological modulator is respiration, but its impact on cerebral blood
Andersson, BM, Andersson, Britt M., Eklund, Anders,, Söderström, Pontus,, Eklund, Anders, Malm, Jan, Malm, J, Karalija, N, Wåhlin, Anders,, Backman, L, Riklund, Katrine, Karalija, Nina,, Malm, Jan,, Andersson, Britt M.,, Soderstrom, P, Bäckman, Lars,, Bäckman, Lars, Riklund, Katrine,, Eklund, A, Wahlin, A, Karalija, Nina, Riklund, K, Söderström, Pontus, Wåhlin, Anders   +23 more
core   +1 more source