Results 51 to 60 of about 5,939,519 (302)

Aerobic exercise training increases cerebral blood flow in postmenopausal women

Artery Research, 2012
Background: Age-related decrease in cerebral blood flow is a risk factor for cognitive decline. Aerobic exercise training improves vascular and cognitive functions.
Nobuhiko Akazawa, Youngju Choi, Asako Miyaki, Jun Sugawara, Ryuichi Ajisaka, Seiji Maeda   +5 more
doaj   +1 more source

Modeling of Cerebral Blood Flow Autoregulation Using Mathematical Control Theory

Mathematics, 2022
A mathematical model of cerebral blood flow in the form of a dynamical system is studied. The cerebral blood flow autoregulation modeling problem is treated as a nonlinear control problem and the potential and applicability of the nonlinear control ...
Alexey Golubev, Andrey Kovtanyuk, Renée Lampe   +2 more
doaj   +1 more source

Multivitamins and minerals modulate whole-body energy metabolism and cerebral blood-flow during cognitive task performance: a double-blind, randomised, placebo-controlled trial [PDF]

, 2016
Background: The brain is by far the most metabolically active organ in the body, with overall energy expenditure and local blood-supply closely related to neural activity.
Jackson, Philippa A., Sarah Dunn (3444305), Dunn, Sarah, Philippa Jackson (3444317), Philippa A. Jackson, Jackson, Philippa, Karl Wishart, Fiona L. Dodd, Gregor Bieri (3444302), Alexandra Carne (3444308), David O. Kennedy, Crystal F. Haskell-Ramsay, Stevenson, Emma J., Wishart, Karl, Emma J. Stevenson, Emma Stevenson (649191), Forster, Joanne, Fiona Dodd (3444311), Crystal Haskell-Ramsay (3444314), Sarah Dunn, Haskell, Crystal, Stevenson, Emma, Dodd, Fiona, Kennedy, David O., David Kennedy (91996), Kennedy, David, Luca Barella, Karl Wishart (2299858), Dodd, Fiona L., Luca Barella (3444299), Bieri, Gregor, Robertson, Bernadette, Haskell-Ramsay, Crystal F., Bernadette C. Robertson, Joanne Forster, Carne, Alexandra, Bernadette Robertson (3444323), Gregor Bieri, Barella, Luca, Alexandra Carne, Robertson, Bernadette C., Joanne Forster (3444320)   +41 more
core   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Glutamate load fosters spreading depolarization under osmotic stress in brain slices

Frontiers in Cellular Neuroscience
IntroductionCerebral edema is a hallmark of lesion progression after acute ischemic stroke (AIS) and a major contributor to the evolution of spreading depolarizations (SDs). SDs trigger extracellular glutamate accumulation and excitotoxic injury, yet the
Rita Frank, Rita Frank, Stephane Marinesco, Ferenc Bari, Ákos Menyhárt, Ákos Menyhárt, Eszter Farkas, Eszter Farkas   +7 more
doaj   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

3D reconstruction of cerebral blood flow and vessel morphology from x-ray rotational angiography [PDF]

, 2009
Three-dimensional (3D) information on blood flow and vessel morphology is important when assessing cerebrovascular disease and when monitoring interventions.
Wächter, I., Wächter, I
core  

Beta1 subunits enable fentanyl‐induced BK channel activation and opioid regulation of cerebral artery diameter

FEBS Open Bio, EarlyView.
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa, Mohammed Nooh, Akhil Geddati, Alex Dopico, Anna N. Bukiya   +4 more
wiley   +1 more source

Theoretical investigation of measuring cerebral blood flow in the adult human head using bolus indocyanine green injection and near-infrared spectroscopy [PDF]

, 2007
To investigate the accuracy of measuring cerebral blood flow (CBF) using a bolus injection of indocyanine green (ICG) detected by near infrared spectroscopy in adult human heads, simulations were performed using a two layered model, representing the ...
Tachtsidis, I, Tachtsidis, I., Delpy, D., Tisdall, M, Leung, T., Smith, M., Elwell, CE, Elwell, C., Delpy, DT, Tisdall, M., Leung, TS, Smith, M   +11 more
core  

Epigallocatechin gallate, cerebral blood flow parameters, cognitive performance and mood in healthy humans: a double-blind, placebo-controlled, crossover investigation [PDF]

, 2012
Objective The aim of the study was to assess the effects of oral ingestion of the ‘green tea’ polyphenol epigallocatechin gallate (EGCG) on cognitive performance, mood and localised cerebral blood flow (CBF) parameters in healthy human adults ...
Haskell, Crystal, Kennedy, David, Wightman, Emma, Forster, Joanne, Veasey, Rachel   +4 more
core   +1 more source