Results 31 to 40 of about 602,288 (337)

A time-invariant visco-elastic windkessel model relating blood flow and blood volume [PDF]

, 2009
The difference between the rate of change of cerebral blood volume (CBV) and cerebral blood flow (CBF) following stimulation is thought to be due to circumferential stress relaxation in veins (Mandeville, J.B., Marota, J.J.A., Ayata, C., Zaharchuk, G ...
Alexander, Bergel, Boas, Burnham, Buxton, Buxton, Deneux, Donahue, Fogliardi, Frank, Friston, Grubb, Herman, Hillman, Huppert, Ito, Ito, Jin, John Mayhew, Jones, Jones, Jones, Kennerley, Kida, Kim, Klabunde, Kong, Kontos, Kontos, Lee, Linehan, Mandeville, Martindale, Mayhew, Molino, Nilsson, Orosz, Paulson, Porciuncula, Remington, Risberg, Roy, Royl, Segers, Smith, Stergiopulos, Ursino, Vakorin, Vazquez, Wang, Westerhof, Ying Zheng, Zheng, Zheng   +53 more
core   +1 more source

Hypothalamic-pituitary dysfunction in severe traumatic brain injury long-term outcomes

Chinese Journal of Contemporary Neurology and Neurosurgery
The incidence of hypothalamic-pituitary dysfunction in patients with severe traumatic brain injury (sTBI) reaches up to 40%. However, it is often masked by clinical manifestations similar to those of sTBI, leading to underdiagnosis and misdiagnosis ...
QIU Bing-hui, DU Jia-shu, ZHONG Qing-lei, ZHUO Jie, HE Shan   +4 more
doaj   +1 more source

Subarachnoid Hemorrhage, Spreading Depolarizations and Impaired Neurovascular Coupling [PDF]

, 2013
Aneurysmal subarachnoid hemorrhage (SAH) has devastating consequences on brain function including profound effects on communication between neurons and the vasculature leading to cerebral ischemia.
Ayata, Cenk, Koide, Masayo, Sukhotinsky, Inna, Wellman, George C.   +3 more
core   +3 more sources

Glutamate load fosters spreading depolarization under osmotic stress in brain slices

Frontiers in Cellular Neuroscience
IntroductionCerebral edema is a hallmark of lesion progression after acute ischemic stroke (AIS) and a major contributor to the evolution of spreading depolarizations (SDs). SDs trigger extracellular glutamate accumulation and excitotoxic injury, yet the
Rita Frank, Rita Frank, Stephane Marinesco, Ferenc Bari, Ákos Menyhárt, Ákos Menyhárt, Eszter Farkas, Eszter Farkas   +7 more
doaj   +1 more source

Cerebral blood flow autoregulation is impaired in schizophrenia [PDF]

, 2017
Patients with schizophrenia have a higher risk of cardiovascular diseases and higher mortality from them than does the general population; however, the underlying mechanism remains unclear.
al, et, Ku, Hsiao-Lun, Lane, Timothy
core  

The effect of end-range cervical rotation on vertebral and internal carotid arterial blood flow and cerebral inflow: a sub analysis of an MRI study [PDF]

, 2015
Introduction: Cervical spine manual therapy has been associated with a small risk of serious adverse neurovascular events, particularly to the vertebral arteries. Sustained end-range rotation is recommended clinically as a pre-manipulative screening tool;
McLeod, Lucy R., Osmotherly, Peter G., Rivett, Darren A., Thomas, Lucy C.   +3 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Laser speckle contrast imaging for blood flow monitoring in predicting outcomes after cerebral ischemia-reperfusion injury in mice

BMC Neuroscience, 2022
Background In the treatment of ischemic cerebral stroke (ICS), most conventional treatments, including carotid endarterectomy and carotid artery stenting, may cause cerebral ischemia-reperfusion injury (CIRI).
Lu Yin, Tengfei Yu, Linggang Cheng, Xinyao Liu, Wei Zhang, Hongxia Zhang, Lijuan Du, Wen He   +7 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Cerebral Blood Flow Autoregulation in Offspring From Experimentally Preeclamptic Rats and the Effect of Age

Frontiers in Physiology, 2022
Preeclampsia is a hypertensive disorder of pregnancy that causes significant, long term cardiovascular effects for both the mother and offspring. A previous study demonstrated that middle cerebral arteries in offspring from an experimental rat model of ...
Emmett E. Whitaker, Emmett E. Whitaker, Emmett E. Whitaker, Abbie C. Johnson, Sarah M. Tremble, Conor McGinn, Nicole DeLance, Marilyn J. Cipolla, Marilyn J. Cipolla, Marilyn J. Cipolla, Marilyn J. Cipolla   +10 more
doaj   +1 more source