Results 41 to 50 of about 5,939,519 (302)

Cerebral artery dilatation maintains cerebral oxygenation at extreme altitude and in acute hypoxia : an ultrasound and MRI study [PDF]

open access: yes, 2011
Transcranial Doppler is a widely used noninvasive technique for assessing cerebral artery blood flow. All previous high altitude studies assessing cerebral blood flow (CBF) in the field that have used Doppler to measure arterial blood velocity have ...
Hirani, Shashivadan P.   +59 more
core   +1 more source

Nomogram for the prediction of surgical site infection following spinal surgery: a multicenter retrospective study

open access: yesFrontiers in Medicine
ObjectiveSurgical site infection (SSI) represents a prevalent postoperative complication associated with spinal surgery, contributing to increased morbidity and mortality rates.
Yang Sun   +15 more
doaj   +1 more source

Lack of effect of pravastatin on cerebral blood flow or parenchymal volume loss in elderly at risk for vascular disease [PDF]

open access: yes, 2005
<p><b>Background and Purpose:</b> Ageing is associated with a decline in cerebral blood flow. Animal studies have shown that cholesterol-lowering therapy with statins might preserve cerebral blood flow (CBF).
Blauw, G.J.   +8 more
core   +1 more source

Non-invasive preoperative MRI-based deep transfer learning radiomics model for predicting meningioma brain invasion

open access: yesFrontiers in Oncology
BackgroundCurrent preoperative assessment of meningioma brain invasion (BI) demands imaging analytical frameworks that optimize computational efficiency while capturing multidimensional tumor-pathology correlations.
Dong Yuan   +10 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Analysis of the efficacy and safety of spinal cord stimulation in the treatment of high-risk diabetic foot

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery
Objective To evaluate the efficacy and safety of spinal cord stimulation (SCS) in the treatment of high-risk diabetic foot. Methods From January 2023 to May 2024, 25 patients with high-risk diabetic foot who underwent SCS were admitted to Tianjin Huanhu ...
CHEN Xiao-chen   +4 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Hypothalamic-pituitary dysfunction in severe traumatic brain injury long-term outcomes

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery
The incidence of hypothalamic-pituitary dysfunction in patients with severe traumatic brain injury (sTBI) reaches up to 40%. However, it is often masked by clinical manifestations similar to those of sTBI, leading to underdiagnosis and misdiagnosis ...
QIU Bing-hui   +4 more
doaj   +1 more source

Sex differences in regional cerebral blood flow

open access: yes, 1988
Regional cerebral blood flow was measured by the 133-xenon inhalation method during resting in 38 healthy men and 38 healthy women matched pairwise for age in the range 18-72 years. The results showed 11% higher global flow level in the women in all ages.
Guido Rosadini   +8 more
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

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