Results 151 to 160 of about 580,671 (347)
Histamine H4 receptor (H4R) antagonist VUF6002 mimics low‐dose X‐ray irradiation in aged Alzheimer's disease (AD) mice, enhancing microglial clearance of amyloid‐beta/hyperphosphorylated tau aggregates and restoring cognition. Microglial H4R deletion activates cAMP/TGF‐β1/Smad3 pathway, enhancing phagocytosis, while TGF‐β receptor 1 deletion abolishes ...
Yi‐Jun Xu +5 more
wiley +1 more source
Effect of cyclandelate on mental function and cerebral blood flow in elderly patients. [PDF]
Jonathan Ball, Alex R. Taylor
openalex +1 more source
The study has developed the first clinically validated hybrid EEG‐fNIRS brain‐computer interface fusion framework that systematically overcomes cross‐subject generalization barriers through a novel Wasserstein metric‐driven neural template selection mechanism.
Danyang Chen +18 more
wiley +1 more source
THE EFFECT OF NITROUS OXIDE ON PULSATILE CEREBRAL IMPEDANCE AND CEREBRAL BLOOD FLOW
Lauri V. Laitinen +2 more
openalex +1 more source
Identifying Tipping Points during Healthy Brain Aging through Single‐Nucleus Transcriptomic Analysis
This study applies single‐nucleus transcriptomics and systems dynamics to uncover nonlinear aging patterns in healthy human brains. By introducing dynamic network biomarker theory, the authors identify a critical tipping point at ages 56–60 during aging, and highlight glial instability as a key mediator.
Peiru Wu +9 more
wiley +1 more source
Nanocatalytic Neuroprotection and Neurological Recovery Post‐Traumatic Brain Injury
This study demonstrates that combining Ce0.7Zr0.3O2 nanozymes with nimodipine enhances neuroprotection after traumatic brain injury. The therapy reduces oxidative stress, neuronal apoptosis, and improves blood–brain barrier integrity, with nanozymes effective at low doses.
Xinjie Hong +10 more
wiley +1 more source
Step Hypocapnia to Separate Arterial from Tissue Pco 2 in the Regulation of Cerebral Blood Flow
John W. Severinghaus, Niels A. Lassen
openalex +1 more source
This study demonstrates that vinburnine, an approved cerebrovascular drug, synergizes with radiotherapy in nasopharyngeal carcinoma (NPC) by modulating EDAR‐NFκB signaling through directly binding to EDAR, leading to triggering apoptosis/pyroptosis, and amplifying CCL5/CX3CL1‐driven T‐cell cytotoxicity.
Jing Chen +9 more
wiley +1 more source

