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Identification of predictive factors for better outcomes in LINAC-based radiation treatment for cerebral cavernous malformation. [PDF]
Kang SM +5 more
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Cerebral Cavernous Malformations
New England Journal of Medicine, 1988Daniele Rigamonti +2 more
exaly +6 more sources
Familial Cerebral Cavernous Malformations [PDF]
Blaine Hart +2 more
exaly +3 more sources
Exceptional Aggressiveness of Cerebral Cavernous Malformation Disease Associated With PDCD10 Mutations [PDF]
PurposeThe phenotypic manifestations of cerebral cavernous malformation disease caused by rare PDCD10 mutations have not been systematically examined, and a mechanistic link to Rho kinase-mediated hyperpermeability, a potential therapeutic target, has ...
Robert Shenkar, Murat Günel, Wang Min
exaly +2 more sources
Pediatric Cerebral Cavernous Malformations
Pediatric Neurology, 2021Cerebral cavernous malformations are the second most common vascular malformations in the central nervous system, and over one-third are found in children. Lesions may be solitary or multiple, be discovered incidentally, be sporadic, or be secondary to familial cavernomatosis or radiation therapy.
Michael Paddock +4 more
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Cerebral Cavernous Malformations
New England Journal of Medicine, 2017A 59-year-old man presented with a 1-year history of progressively worsening headaches. Imaging revealed multiple lesions, and genetic analysis confirmed a diagnosis of the familial cerebral cavernous malformation syndrome.
Ithamar, Ganmore, Anat, Achiron
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Evaluating Strategies for the Treatment of Cerebral Cavernous Malformations
Cerebral cavernous malformations are common vascular lesions of the central nervous system that predispose to seizures, focal neurological deficits, and potentially fatal hemorrhagic stroke.
Kevin J Whitehead
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Genetics of cerebral cavernous malformations
Current Neurology and Neuroscience Reports, 2005The past few years have seen rapid advances in our understanding of the genetics and molecular biology of cerebral cavernous malformations (CCM). This article summarizes the recent cloning of the CCM1, CCM2, and CCM3 genes, which are responsible for autosomal dominant CCM, and also describes current hypotheses for their roles in integrin and p38 ...
Nicholas W, Plummer +2 more
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Cerebral cavernous malformations
Neurology, 2002To find mutations in the recently identified additional exons of the Krit1 gene that causes CCM1, a disease characterized by the formation of cerebral cavernous malformations (CCM). To determine the relative frequency with which Krit1 mutations cause CCM as well as recharacterize the mutations reported in the literature.Twenty-seven families and 11 ...
D J, Verlaan +5 more
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Cerebral Cavernous Malformations
Archives of Neurology, 1989To the Editor. —In the February 1989 issue of theArchives, Allard et al 1 described several members of a family who had multiple lesions noted on magnetic resonance imaging that were termed arteriovenous malformations . These lesions, however, have the characteristic magnetic resonance imaging appearance of cavernous malformations (angiomas), another ...
K. S. Lee, R. F. Spetzler
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