Results 41 to 50 of about 1,916 (204)

Long-term outcomes of untreated cerebral cavernous malformations: a prospective, population-based cohort study. [PDF]

Lancet Reg Health Eur
Sandmann ACA, Vandertop WP, White PM, Verbaan D, Coutinho JM, Al-Shahi Salman R, Scottish Audit of Intracranial Vascular Malformations (SAIVMs) Steering Committee.   +6 more
europepmc   +3 more sources

Maltese study of intracranial vascular malformations [PDF]

, 2018
Intracranial vascular malformations (IVMs) are responsible for 49% of spontaneous intraparenchymal brain haemorrhage in patients under 40 years of age.
Chircop, Charmaine, Dalli, Theresia, Mallia, Maria   +2 more
core   +1 more source

Cerebral hemorrhage from an incidental cavernous malformation occurring at the progressive stage of immunoglobulin G4-related disease

Interdisciplinary Neurosurgery, 2018
Immunoglobulin G4-related disease (IgG4-RD) is an immune-mediated condition that can affect almost any organ. In this case, a cerebral cavernous malformation (CCM) was incidentally detected by magnetic resonance imaging (MRI) performed to assess the ...
Junnichi Ayabe, M.D., Naoyuki Noda, M.D., Yuusuke Tsuchiya, M.D., Souta Toginn, M.D., Yoshihide Tanaka, M.D., Hiroyuki Mishima, M.D.   +5 more
doaj   +1 more source

Varying clinical presentations of familial cerebral cavernous malformations (CCMs) and spinal cord cavernous malformations (SCCMs)

Radiology Case Reports, 2012
We present a family afflicted by both extensive cerebral cavernous malformations (CCMs) and spinal cord cavernous malformations (SCCMs). These may be inherited in an autosomal dominant pattern or occur sporadically. The presentation varies and may include a multitude of clinical symptoms separated in time and space.
Nicholas-Bublick, Selena, Koffman, Boyd M.   +1 more
openaire   +2 more sources

A Novel PKD1 Mutation Associated With Autosomal Dominant Kidney Disease and Cerebral Cavernous Malformation

Frontiers in Neurology, 2018
Autosomal dominant polycystic kidney disease (ADPKD) is a genetic disorder characterized by the presence of renal cysts and specific extrarenal abnormalities.
Christian Thomas, Andrea Zühlsdorf, Konstanze Hörtnagel, Lejla Mulahasanovic, Oliver M. Grauer, Philipp Kümpers, Heinz Wiendl, Sven G. Meuth   +7 more
doaj   +1 more source

Assessing the association of common genetic variants in EPHB4 and RASA1 with phenotype severity in familial cerebral cavernous malformation

Molecular Genetics & Genomic Medicine, 2021
Background To investigate whether common variants in EPHB4 and RASA1 are associated with cerebral cavernous malformation (CCM) disease severity phenotypes, including intracranial hemorrhage (ICH), total and large lesion counts. Methods Familial CCM cases
Foram Choksi, Shantel Weinsheimer, Jeffrey Nelson, Ludmila Pawlikowska, Christine K. Fox, Atif Zafar, Marc C. Mabray, Joseph Zabramski, Amy Akers, Blaine L. Hart, Leslie Morrison, Charles E. McCulloch, Helen Kim   +12 more
doaj   +1 more source

Zebrafish models of cerebrovascular disease [PDF]

, 2014
Perturbations in cerebral blood flow and abnormalities in blood vessel structure are the hallmarks of cerebrovascular disease. While there are many genetic and environmental factors that affect these entities through a heterogeneous group of disease ...
Peterson, Randall T, Walcott, Brian P
core   +1 more source

Readmissions in Patients with Cerebral Cavernous Malformations (CCMs): A National Readmission Database (NRD) Study [PDF]

, 2021
Abstract BACKGROUND Cerebral cavernous malformations (CCMs) are microvascular CNS lesions prone to hemorrhage leading to neurological sequela such as stroke and seizure. A subset of CCM patients have aggressive disease leading to multiple bleeding events, likely resulting multiple hospitalizations ...
Akhil Padarti, Amod Amritphale, Javed Khader Eliyas, Daniele Rigamonti, Jun Zhang   +4 more
openaire   +1 more source

An Insight into the microRNAs Associated with Arteriovenous and Cavernous Malformations of the Brain

Cells, 2021
Background: Brain arteriovenous malformations (BAVMs) and cerebral cavernous malformations (CCMs) are rare developmental anomalies of the intracranial vasculature, with an irregular tendency to rupture, and as of yet incompletely deciphered ...
Ioan Alexandru Florian, Andrei Buruiana, Teodora Larisa Timis, Sergiu Susman, Ioan Stefan Florian, Adrian Balasa, Ioana Berindan-Neagoe   +6 more
doaj   +1 more source

Lifetime Risk of First Symptomatic ICH or Seizure in Familial Cerebral Cavernous Malformations: A Multicenter Patient Data Analysis. [PDF]

Neurology
Dammann P, Santos AN, Mavarani L, Guey S, Chabriat H, Herve D, Croft J, Renteria M, Jang D, Zhang J, Li D, Wu Z, Weng JC, Petracca A, Fusco C, D'Agruma L, Castori M, Rath M, Pilz RA, Felbor U, Steinberg GK, Gu J, Bervini D, Goldberg J, Raabe A, Cervio A, Villamil F, Rosales J, Rauschenbach L, Riess C, Oppong MD, Karadachi H, Ahmadipour Y, Wrede KH, Jabbarli R, Deuschl C, Li Y, Santos Piedade G, Köhrmann M, Frank B, Wälchli T, Schmidt B, Overstijns M, Beck J, Fung C, Al-Shahi Salman R, Flemming KD, Lanzino G, Zafar A, Weinsheimer S, Nelson J, Zabramski JM, Akers A, Morrison L, McCulloch CE, Kim H, Sure U, Brain Vascular Malformation Consortium Cerebral Cavernous Malformation Investigator Group.   +57 more
europepmc   +3 more sources