Results 171 to 180 of about 1,178,145 (310)

Extracranial-intracranial bypass surgery for intracranial aneurysm of the anterior cerebral circulation: A systematic review and meta-analysis. [PDF]

Front Neurol, 2023
Chen Y, Chen P, Duan G, Li R, Li Z, Guo G.   +5 more
europepmc   +1 more source

Acute toxicity of ADB‐CHMINACA ‐ a case series of patients with pronounced central nervous symptoms including the posterior reversible encephalopathic syndrome

British Journal of Clinical Pharmacology, EarlyView.
Aim This report presents a series of 16 patients who were admitted to the emergency department following confirmed intake of the potent synthetic cannabinoid ADB‐CHMINACA. Methods The cases are drawn from a prospective observational study following the recreational use of synthetic cannabinoids.
Maren Hermanns‐Clausen, Michaela Sommer, Annette Zschiesche, Verena Angerer, Martin Scheu, Florian Eyer, Johannes Nadler, Volker Auwärter   +7 more
wiley   +1 more source

Risk score for futile recanalization: integrating cerebral circulation time and collateral cascade. [PDF]

Front Aging Neurosci
Song X, Zhao GF, Qin YL, Bai ZB, Ji JJ, Deng G.   +5 more
europepmc   +1 more source

Regulation of the Cerebral Circulation During Development. [PDF]

Compr Physiol, 2021
Koehler RC.
europepmc   +1 more source

Monitoring pharmacodynamic and molecular drug targets in liquid biopsy: Exploratory study in liver cancer with modelling of EGFR Receptor engagement

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Liquid biopsy is minimally invasive (compared with tissue biopsy) and has previously been used to generate systems data regarding drug elimination via hepatic enzymes and transporters. This study extends quantitative assessment of systems parameters in liquid biopsy to pharmacodynamic (PD) and disease markers relevant to cancer development
Zubida M. Al‐Majdoub, Armin Sepp, Amin Rostami‐Hodjegan, Brahim Achour   +3 more
wiley   +1 more source

Editorial for cerebral circulation cognition & behavior special issue on brain health. [PDF]

Cereb Circ Cogn Behav
Gorelick PB, Wallin A.
europepmc   +1 more source

Corrigendum to 'Cerebral circulation II: pathophysiology and monitoring' [BJA Education 22 (2022) 282-8]. [PDF]

BJA Educ, 2022
Lavinio A.
europepmc   +1 more source

The integrated Lei‐CNS PBPK‐PD model effectively predicts clozapine brain disposition and D2 receptor occupancy in humans

British Journal of Clinical Pharmacology, EarlyView.
Aim Clozapine, used for treatment‐resistant schizophrenia, has a narrow therapeutic window and highly variable plasma pharmacokinetics (PK), necessitating careful monitoring. Direct measurement of unbound brain PK in humans is unethical. To develop a physiologically based pharmacokinetic–pharmacodynamic (PBPK‐PD) model to predict clozapine brain ...
Mengxu Zhang, Thomas I. F. H. Cremers, Vivi Rottschäfer, Elizabeth C. M. de Lange   +3 more
wiley   +1 more source

The brain baroreflex - a hidden guardian of the cerebral circulation. [PDF]

J Physiol
Osei-Boateng C, McCrone JC, Tymko MM.
europepmc   +1 more source

Ultrasound Evaluation of Extracranial Cerebral Circulation (The Common, External and Internal Carotid Artery) in Different Breeds of Dogs. [PDF]

Animals (Basel), 2023
Ševčíková MK, Figurová M, Ševčík K, Hluchý M, Domaniža M, Lapšanská M, Drahovská Z, Žert Z.   +7 more
europepmc   +1 more source