Results 281 to 290 of about 1,509,767 (359)

The Posterior Cerebral Circulation

Journal of the Royal College of Physicians of London, 1973
openaire   +2 more sources

Prenatal Exome Sequencing Identifies Dual Maternal‐Fetal Diagnosis of HbF Mission Bay, a Novel HBG2 Variant Associated With Methemoglobinemia, Hypoxia and Hemolytic Anemia

Prenatal Diagnosis, EarlyView.
ABSTRACT Prenatal exome sequencing (ES) can establish rare genetic diagnoses in a fetus but may also lead to occult genetic diagnosis in a biological parent. We present a case of dual fetal and maternal diagnosis by prenatal ES, in a fetus with unexplained anemia and in a pregnant patient with sickle cell disease (SCD) and recurrent unexplained hypoxia.
Matthew A. Shear, Billie Lianoglou, Ugur Hodoglugil, W. Patrick Devine, Ashutosh Lal, Juan Gonzalez, Teresa N. Sparks   +6 more
wiley   +1 more source

Pregnancy Complications in Fetal Congenital Heart Disease: A Result of Common Early Developmental Pathways Rather Than Fetal Hemodynamics

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective The aim of this study was to compare placenta‐related complications (adverse placental syndrome) between different types of fetal CHD based on cardiac hemodynamics. Method All CHD cases diagnosed prenatally by fetal ECHO during 2009–2023 were selected.
Maartje C. Snoep, Damla Demir, Anouk M. C. Roestenburg, Eva Pajkrt, Elisabeth van Leeuwen, Ingeborg H. Linskens, Ingmar Knobbe, Sally‐Ann Clur, Lieke Rozendaal, Lotte E. van der Meeren, Monique C. Haak   +10 more
wiley   +1 more source

Plasma Proteomic Profiling of a Group of Anxious Dogs by LC‐MS/MS: A Case–Control Study

PROTEOMICS – Clinical Applications, EarlyView.
ABSTRACT Purpose Anxiety is the most common underlying cause of behavioral problems in dogs, which remain a top reason for relinquishment and euthanasia. Despite its high prevalence, anxiety is often underdiagnosed, partly due to a limited understanding of biological processes and absence of diagnostic biomarkers.
Claudia Gaither, Robert Popp, Christoph H. Borchers, Francis Beaudry, Marion Desmarchelier   +4 more
wiley   +1 more source

An Up‐to‐Date Review of Traditional Chinese Medicine in the Treatment of Atherosclerosis: Components, Mechanisms, and Therapeutic Potentials

Phytotherapy Research, EarlyView.
Traditional Chinese medicine in atherosclerosis: multi‐target modulation of pathogenesis. ABSTRACT Atherosclerosis is a chronic inflammatory disease and a major global health concern. In recent years, traditional Chinese medicines (TCMs) have demonstrated multi‐target therapeutic potential against atherosclerosis by modulating inflammatory responses ...
Dilaram Nijat, Qingzhe Zhao, Gulhasal Abdurixit, Jianhua He, Haipeng Liu, Jinyao Li   +5 more
wiley   +1 more source

Micro‐ and nanomotors in biomedical applications

Responsive Materials, EarlyView.
Micro‐ and nanomotors (MNMs), as autonomous devices converting chemical or external energy into mechanical propulsion, have emerged as transformative drug delivery platforms in biomedicine. This review systematically outlines the design principles governing MNMs' propulsion and operation, highlights the applications of MNMs in disease treatment, and ...
Xiangyu Meng, Yuqi Tang, Quan Li
wiley   +1 more source

Bridging the Gap: How Organ‐on‐a‐Chip Technology Facilitates the Battle against Glioma

Small Science, EarlyView.
This review critically evaluates current state‐of‐the‐art in vitro glioma models especially glioma‐on‐a‐chip models based on readout capability, performance, and physiological relevance. It summarizes the key parameters and proposes a practical framework to guide researchers in selecting the most suitable preclinical models for glioma studies.
Su Liu, Zhenyu Gong, Dairan Zhou, Vanesa Ayala‐Nunez, Tao Xu, Peter Wick   +5 more
wiley   +1 more source

Cord blood levels of insulin‐like growth factor‐1 and insulin‐like growth factor binding protein‐3 correlate with perinatal brain development in fetal congenital heart disease

Ultrasound in Obstetrics &Gynecology, EarlyView.
Abstract Objectives Neonates with critical congenital heart disease (CCHD) are at risk for adverse early brain development and long‐term neurodevelopmental sequelae. Insulin‐like growth factor‐1 (IGF‐1) and insulin‐like growth factor binding protein‐3 (IGFBP‐3) are essential contributors to brain growth and maturation.
M. Nijman, N. H. P. Claessens, J. M. P. J. Breur, L. Reijn, N. J. G. Jansen, I. M. van Ooijen, R. de Heus, C. H. Nijboer, M. N. Bekker, M. J. N. L. Benders, R. Stegeman, J. E. G. Vaes, the CHD LifeSpan Study Group Utrecht, Joppe Nijman, Thomas Alderliesten, Rian Bosch, Roelie M. Wösten‐van Asperen, Henriette ter Heide, Trinette J. Steenhuis, Martijn G. Slieker, Gabrielle G. van Iperen, Kim van Loon, Boyd V. Martherus, Erik Koomen, Abraham van Wijk, Paul H. Schoof, Hanna Talacua, Neeltje Crombag, Bauke M. Adriaanse, Niels Blanken, Rutger A.J. Nievelstein, Monique M.J. van Schooneveld, Lotte Soeters, Maaike C.A. Sprong   +33 more
wiley   +1 more source

Brain metastasis in non‐small cell lung cancer: High‐risk factors and predictive models

VIEW, EarlyView.
Artificial intelligence (AI) can integrate of data to predict brain metastases (BM) in non‐small cell lung cancer (NSCLC). AI algorithms are employed to analyze these multifaceted datasets, enabling the identification of complex patterns and correlations that may not be apparent through traditional analytical methods.
Chen Gong, Ben Zhao, Shuangshuang Mao, Qingxu Liu, Yuanyuan Zhao, Yiwen Liu, Yao Luo, Qianxia Li   +7 more
wiley   +1 more source

Free Foetal Haemoglobin in Severe Early‐Onset Foetal Growth Restriction: A Prospective Multi‐Centre Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To assess foetal circulating free foetal haemoglobin (fHbF) levels and heme defences, correlated to foetal circulatory biometry and foetal sex in severe early‐onset foetal growth restriction (FGR). Design, Setting and Population A prospective study severe early‐onset foetal growth restriction pregnancies with close clinical ...
Adam Brook, Georgia Baynes, Jonathan Scargill, Angelos Evangelinos, Charlotte Brennan‐Richardson, Freya Dow, Yuval Ginsberg, Tal Weissbach, Jana Brodszki, Eva Hansson, Anke Diemert, Kurt Hecher, Katarzyna Maksym, Neil Marlow, Rebecca N. Spencer, Anna L. David, Stefan R. Hansson, Paul Brownbill   +17 more
wiley   +1 more source