Results 101 to 110 of about 7,738 (248)

The interplay between pulsatility, sympathetic regulation and renal physiology: Implications for left ventricular assist devices

open access: yesExperimental Physiology, EarlyView.
Abstract Left ventricular assist devices have gained traction both as a bridge therapy and as a destination therapy in the management of heart failure. Many of these devices reinstate blood flow in a continuous manner as opposed to the pulsatile flow present in normal physiology.
Tania Warnakulasuriya   +2 more
wiley   +1 more source

Protein kinase Cδ and pharmacomechanical coupling: Re‐envisioning cerebral vascular control

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Top, G‐protein coupled receptors trigger electromechanical and pharmacomechanical coupling, the latter via signal transduction pathways that inhibit myosin light chain phosphatase. Middle, the relative contribution of electromechanical and pharmacomechanical coupling varies with the concentration and the vessel area to which ...
Nadia Haghbin   +10 more
wiley   +1 more source

Temporal dissociation between cerebral blood flow and brain tissue oxygenation during CPR: observations from a porcine model. [PDF]

open access: yesKorean J Anesthesiol
Silverman MG   +8 more
europepmc   +1 more source

High‐altitude headache: Insights into pathophysiology and potential treatment implications

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend High‐altitude headache occurs during prolonged exposure to low oxygen, such as during ascent to high altitude. Several risk factors increase its likelihood, with the degree of hypoxia, often driven by rapid ascent to greater altitudes, being the most prominent factor.
Marika Falla   +3 more
wiley   +1 more source

Preeclampsia‐derived small extracellular vesicles disrupt blood–brain barrier integrity and activate glial cells in vitro

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend This study assessed the impact of plasma‐derived small extracellular vesicles (sEVs) from healthy pregnant women and those diagnosed with late‐onset preeclampsia (PE) on the blood–brain barrier (BBB) integrity and glial cell response. PE patients had higher sEV concentrations than healthy controls.
Julián Henao‐Restrepo   +7 more
wiley   +1 more source

A constitutive modelling framework for applications to in vivo longitudinal data: Evaluation in a 60‐day head‐down bed rest study on arterial function

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend We proposed a computational constitutive modelling framework that leverages longitudinal acquisitions of haemodynamic waveforms at multiple arterial locations to achieve a biomechanical characterisation of their (micro)structural remodelling processes.
Alessandro Giudici   +9 more
wiley   +1 more source

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