Results 111 to 120 of about 16,861 (284)
Experimental Physiology, EarlyView.Abstract A reduction in cerebral blood flow (CBF) has been observed during spaceflight and bed rest. We aimed to examine the magnitude and regional heterogeneity of the decrease in CBF during bed rest compared to posture changes on Earth. Seventeen participants (age, 29 ± 9 years, 7 females) were studied in the upright and supine posture and over 3 ...
Carmen Possnig +8 more
wiley +1 more source
Experimental Physiology, EarlyView.Abstract This narrative review highlights the impact of exercise on vascular health in females over the lifespan with an emphasis on puberty, pregnancy and menopause. These events encompass substantial changes in sex hormone levels, particularly oestrogens and progesterone.
Kathleen B. Miller +2 more
wiley +1 more source
A multiphysics computer modeling framework in support of the quest for reliable and robust local arterial stiffness assessment [PDF]
, 2014 Caenen, Annette +8 more
core +1 more source
Adaptation to prolonged bedrest in man: A compendium of research [PDF]
A compilation of major studies that describe the clinical observations and elucidate the physiological mechanisms of the adaptive process of man undergoing prolonged bed rest is presented.
Dorchak, K. J. +3 more
core +1 more source
Experimental Physiology, EarlyView.Abstract Central artery stiffening increases the haemodynamic pulsations transmitted downstream towards target organs, including the brain. While recent evidence suggests that long duration spaceflight is associated with reduced common carotid artery (CCA) distensibility, cerebrovascular pulsatility has not been extensively characterized in astronauts.
Roxanne Fournier +5 more
wiley +1 more source
Uncovering the impact of the cardiovascular system on cerebrovascular health using MRI
Experimental Physiology, EarlyView.Abstract Human cerebrovasculature is finely tuned to enable local changes in blood flow to meet the brain's demands, whilst protecting the brain from systemic changes in blood pressure, both acutely during a heartbeat and chronically over time. This review summarises cerebrovascular structure and function, their role in disease and neurodegeneration ...
Ian D. Driver, Kevin Murphy
wiley +1 more source
Optimizing cerebrovascular endothelial health through shear stress modulation
Experimental Physiology, EarlyView.Abstract The endothelium plays a pivotal role in regulating cerebrovascular blood flow, and its dysfunction increases the risk of cerebrovascular disease. Endothelial shear stress, a primary mechanical stimulus for endothelial nitric oxide production, is a key modulator of vascular adaptation.
Erika Iwamoto +2 more
wiley +1 more source
The LifeV library: engineering mathematics beyond the proof of concept [PDF]
, 2017 LifeV is a library for the finite element (FE) solution of partial differential equations in one, two, and three dimensions. It is written in C++ and designed to run on diverse parallel architectures, including cloud and high performance computing ...
Bertagna, Luca +4 more
core +1 more source
Experimental Physiology, EarlyView.Abstract Dynamic cerebral autoregulation (dCA) stabilises cerebral blood flow (CBF) against rapid fluctuations in perfusion pressure and may serve as a key physiological mediator of cognitive function. Inhibitory executive function, a core domain essential for goal‐directed behaviour, is influenced by modifiable lifestyle factors such as physical ...
Hayato Tsukamoto, Damian M. Bailey
wiley +1 more source
Experimental Physiology, EarlyView.Abstract Cerebral blood flow (CBF) is essential for sustaining neuronal metabolism and cognitive performance; however, the precise relationship between perfusion and cognition remains unclear. Although ageing and disease are associated with progressive declines in CBF and cognitive impairment, the acute effects of altered CBF under environmental ...
Hiroki Nakata +2 more
wiley +1 more source