Results 181 to 190 of about 602,933 (343)

Dissecting the Factors Involved in the Locomotion Mode of Neuronal Migration in the Developing Cerebral Cortex [PDF]

open access: hybrid, 2009
Yoshiaki Nishimura   +6 more
openalex   +1 more source

Flipping the Switch: MeCP2‐Mediated Lactylation Rewires Microglial Metabolism and Inflammation via the HK2/mTOR Axis in Poststroke Neuroinflammation

open access: yesAdvanced Science, EarlyView.
Stroke‐induced lactate accumulation promotes p300‐mediated lactylation of methyl‐CpG binding protein 2 (MeCP2) at lysine 210, which reprograms microglial metabolism toward glycolysis and activates the hexokinase 2 (HK2)/mTOR axis. This cascade promotes proinflammatory responses and impairs neurofunctional outcomes.
Zengyu Zhang   +12 more
wiley   +1 more source

Pre-infection cerebral cortex structure predicts murine sepsis outcome. [PDF]

open access: yesPLoS One
Gallant RM   +5 more
europepmc   +1 more source

Spatiotemporal Organization and Cross-Frequency Coupling of Sleep Spindles in Primate Cerebral Cortex [PDF]

open access: bronze, 2016
Saori Takeuchi   +5 more
openalex   +1 more source

Organic Electrochemical Transistors in Tissue‐Interfaced Bioelectronics

open access: yesAdvanced Science, EarlyView.
This article reviews the design, fabrication, and biological application of organic electrochemical transistors (OECTs), emphasizing their potential in tissue‐interfaced bioelectronics. It covers the fundamental principles of OECTs, strategies for enhancing tissue interfacing, and the development of skin‐mounted and implantable systems.
Ruixiang Bai, Zeyu Zhao, Feng Yan
wiley   +1 more source

Integrated ERK‐PKA‐YAP/TAZ‐SHH Signaling Orchestrates Cortical Radial Glia Identity and Lineage Diversification

open access: yesAdvanced Science, EarlyView.
This study shows that ERK/PKA upregulation in mammalian cortical radial glia (RGs) sustains neurogenesis and suppresses gliogenesis. YAP/TAZ activation promotes ependymal cell formation, while enhanced SHH‐SMO signaling induces astrocyte, oligodendrocytes, and olfactory bulb interneuron generation.
Zhuangzhi Zhang   +13 more
wiley   +1 more source

A Tracking Approach to Parcellation of the Cerebral Cortex [PDF]

open access: bronze, 2005
Chris Adamson   +5 more
openalex   +1 more source

HIDF: Integrating Tree‐Structured scRNA‐seq Heterogeneity for Hierarchical Deconvolution of Spatial Transcriptomics

open access: yesAdvanced Science, EarlyView.
The prevailing neglect of cellular hierarchies in current spatial transcriptomics deconvolution often obscures cellular heterogeneity and impedes the identification of fine‐grained subtypes. To address this issue, HIDF employs a cluster‐tree and dual regularization to systematically model cellular hierarchical structures.
Zhiyi Zou   +5 more
wiley   +1 more source

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