Results 181 to 190 of about 1,638,797 (414)

Rational Design of Inner Ear Drug Delivery Systems

open access: yesAdvanced Science, EarlyView.
Hearing loss is a common disease affecting many people, and inner ear lesions are one of the most important causes. This review focuses on the treatment of inner ear hearing loss by drug delivery systems. It includes the current methods and technologies developed, and it predicts possible directions.
Xiayidan Maimaitikelimu   +5 more
wiley   +1 more source

New hallmarks of criticality in recurrent neural networks [PDF]

open access: yesarXiv, 2016
A rigorous understanding of brain dynamics and function requires a conceptual bridge between multiple levels of organization, including neural spiking and network-level population activity. Mounting evidence suggests that neural networks of cerebral cortex operate at criticality. How operating near this network state impacts the variability of neuronal
arxiv  

Epileptiform Activity and Seizure Risk Follow Long‐Term Non‐Linear Attractor Dynamics

open access: yesAdvanced Science, EarlyView.
This study leverages the HAVOK framework to model long‐term, nonlinear attractor dynamics underlying epileptiform activity and seizure risk in epilepsy patients. By identifying key forcing mechanisms driving chaotic transitions, the findings improve seizure risk forecasting over multi‐day cycles and provide a pathway for personalized, data‐driven ...
Richard E Rosch   +4 more
wiley   +1 more source

CEREBRAL CORTEX OF NEWBORN ANIMALS [PDF]

open access: yesThe American Journal of the Medical Sciences, 1886
n ...
openaire   +3 more sources

The human and mammalian cerebrum scale by computational power and information resistance

open access: yes, 2013
The cerebrum of mammals spans a vast range of sizes and yet has a very regular structure. The amount of folding of the cortical surface and the proportion of white matter gradually increase with size, but the underlying mechanisms remain elusive.
de Lussanet, Marc H. E.
core  

Implantable Self‐Powered Systems for Electrical Stimulation Medical Devices

open access: yesAdvanced Science, EarlyView.
In this paper, the design strategy and clinical application of ISS are discussed in depth from four aspects: the design and optimization of the energy collection module, the selection and preparation of adaptive electrode materials, the innovation of system design strategy, and the biological effect of electrical stimulation of ISS.
Xi Cui, Li Wu, Chao Zhang, Zhou Li
wiley   +1 more source

Evaluation of a novel PET tracer [18F]-Florbetazine for Alzheimer's disease diagnosis and β-amyloid deposition quantification

open access: yesNeuroImage
[18F]-Florbetazine ([18F]-92) is a selective PET tracer for β-amyloid (Aβ) depositions with a novel diaryl-azine scaffold to reduce lipophilicity and to achieve higher gray-to-white matter contrast.
Meiqi Wu   +15 more
doaj  

Astrocyte layers in the mammalian cerebral cortex revealed by a single-cell in situ transcriptomic map

open access: yesNature Neuroscience, 2020
O. Bayraktar   +24 more
semanticscholar   +1 more source

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