Advanced Science, EarlyView.This study explores the therapeutic potential of iNSC‐Exo via local and systemic delivery in TBI mice. It is found that iNSC‐Exo enhances NRXN signaling through Microglia_Nrg3 and Microglia_Rarb, effectively promoting functional and neurological recovery, suggesting a new therapeutic strategy for TBI. Abstract Traumatic brain injury (TBI) poses serious
Jiaojiao Li +9 more
wiley +1 more source
Decoding chronic pain: the glutamate-GABA tug of war in the cerebral cortex. [PDF]
Front Mol NeurosciHuang D +6 more
europepmc +1 more source
Reoxygenation of asphyxiated newborn piglets: administration of 100% oxygen causes significantly higher apoptosis in cortical neurons, as compared to 21%. [PDF]
, 2014 Di Felice E +11 more
core +1 more source
Neural Response Reliability as a Marker of the Transition of Neural Codes along Auditory Pathways
Advanced Science, EarlyView.Decoding sound from neural activity in mice reveals a striking shift in how the brain encodes sound: from precise but redundant timing codes in early auditory areas to efficient, synergistic rate‐based codes in the cortex. This transformation highlights a robust neural strategy for turning complex acoustic input into coherent perception across the ...
Alexa Buck +7 more
wiley +1 more source
Blood flow in the human cerebral cortex: Large-scale pial vascularization and 1D simulation. [PDF]
PLoS Comput BiolZilves EG +5 more
europepmc +1 more source
Relation between the size and form of potentials evoked by sensory stimulation and the background electrical activity in the cerebral cortex of the rat [PDF]
, 1964 Lynn J. Bindman +2 more
openalex +1 more source
Advanced Science, EarlyView.SpaBatch is an end‐to‐end multi‐slice spatial transcriptomics data integration framework. It simultaneously performs embedding learning, spatial feature denoising and reconstruction, batch effect correction, and spatial domain optimization, effectively correcting batch effects and achieving accurate 3D spatial domain identification.
Jinyun Niu +5 more
wiley +1 more source
Preimplantational ethanol exposure causes disturbances in gene expression and abnormalities in cerebral cortex morphogenesis and behavior. [PDF]
Toxicol SciSugiyama R, Tanizaki M, Komada M.
europepmc +1 more source
The interaction between atropine sulphate and a proteolipid from cerebral cortex studied by light scattering [PDF]
, 1969 E. De Robertis +2 more
openalex +1 more source
Advanced Science, EarlyView.This study establishes a mandibular asymmetry (MA) mouse model that recapitulates chronic orofacial pain and anxiety comorbidity. Anterior cingulate cortex (ACC) hyperactivation and synaptic dysfunction are identified as central neural mechanisms underlying these pathologies, with chemogenetic inhibition of ACC CaMKII+ neurons effectively reversing ...
Zhaoyichun Zhang +19 more
wiley +1 more source