Results 201 to 210 of about 594,163 (347)

Refractory Status Epilepticus and Therapeutic Uncertainties: a Comprehensive Review on Targeting Neuroinflammation and Rationale for Developing a Platform Trial

open access: yesAdvanced Science, EarlyView.
Refractory status epilepticus (RSE) is a life‐threatening neurological emergency with high rates of death and long‐term disability, but treatments for it are often based on limited evidence. RSE is now understood to involve neuroinflammation, which has led to the exploration of anti‐inflammatory and immunomodulatory agents like Tocilizumab. Traditional
Shanika Samarasekera   +12 more
wiley   +1 more source

Histopathological Alterations and Dysregulation of Type I Interferon Signaling in the Human Cerebral Cortex During Severe Dengue. [PDF]

open access: yesJ Med Virol
Castro LM   +10 more
europepmc   +1 more source

Bio‐Inspired SA‐FA Bionic Dual Receptor Electronic Skin for Intelligent Gesture and Material Cognition Systems Enhanced by Static‐Dynamic Mutual Interaction

open access: yesAdvanced Science, EarlyView.
In this work, bionic dual receptor (BDR) e‐skin based on the iontronic and triboelectric effects is proposed, inspired by the slow‐adapting and fast‐adapting receptors. Motivated by intelligent software algorithms and high‐speed hardware circuits, the proposed intelligent autonomous material cognition system integrated with the EDB e‐skin can ...
Hao Li   +5 more
wiley   +1 more source

Procyanidin B3 and Its Derivatives Alleviate Neuronal Injury by Targeting G3BP1 for Ischemic Stroke Therapy

open access: yesAdvanced Science, EarlyView.
Ischemic stroke is a serious disease with high rates of mortality and disability, but there is a lack of novel therapeutic targets and agents for it. Now it is shown that Ras GTPase‐activating protein SH3 domain‐binding protein 1 (G3BP1) has the potential to serve as a therapeutic target for ischemic stroke.
Heyanhao Zhang   +10 more
wiley   +1 more source

The ciliary kinesin KIF7 controls the development of the cerebral cortex by acting differentially on SHH signaling in dorsal and ventral forebrain. [PDF]

open access: yesElife
Pedraza M   +9 more
europepmc   +1 more source

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