Results 241 to 250 of about 594,163 (347)

SpaBalance: Balanced Learning for Efficient Spatial Multi‐Omics Decoding

open access: yesAdvanced Science, EarlyView.
SpaBalance is a computational framework that harmonizes multi‐omics learning via gradient equilibrium and dual‐stream feature decomposition, achieving superior clustering accuracy, biological interpretability, and scalable integration of three or more spatial omics modalities.
Yingbo Cui   +8 more
wiley   +1 more source

Repurposing of Chemokine Antagonists for Combined Phase‐Resolved Spinal Cord Injury Treatment

open access: yesAdvanced Science, EarlyView.
Spinal cord injury (SCI) in mammals is accompanied by a massive cytokine storm in cerebrospinal fluid, mainly driven by CXCL1, IL‐6, and CCL2‐5. Sub‐acute phase is mostly associated with IL‐2, IL‐7, CCL22, and CX3CL1, whereas TNFα and IL17α permanently persists in CNS even weeks following SCI.
Alexey A. Belogurov Jr.   +20 more
wiley   +1 more source

Nanozymes for Non‐Neoplastic Diseases: Catalytic Therapy Redefined

open access: yesAggregate, EarlyView.
Non‐neoplastic diseases pose a significant health burden. Nanozymes, enzyme‐like nanomaterials, offer promising strategies for regulating oxidative stress and inflammation. This review explores their development, structure–function relationships, and therapeutic potential, with a focus on precision medicine through targeted delivery and multimodal ...
Ling Mei   +8 more
wiley   +1 more source

Bioinspired Engineering beyond Homeostasis

open access: yesAdvanced Intelligent Systems, EarlyView.
This perspective article introduces systems biology as the unifying theoretical framework behind bioinspired engineering. As an example, it explores how disruptions in multiscale biological systems, associated with pathological states, can be viewed as localized failure modes of biological cooperation showing emergent advantages that can inspire ...
Rosalia Moreddu
wiley   +1 more source

Microendovascular Neural Recording from Cortical and Deep Vessels with High Precision and Minimal Invasiveness

open access: yesAdvanced Intelligent Systems, EarlyView.
Intravascular electroencephalography (ivEEG) using micro‐intravascular electrodes was developed. Cortical‐vein ivEEG showed a higher signal‐to‐noise ratio and finer spatial resolution of somatosensory evoked potentials (SEPs) than superior sagittal sinus ivEEG, and deep‐vein ivEEG captured clear visual evoked potentials.
Takamitsu Iwata   +15 more
wiley   +1 more source

Home - About - Disclaimer - Privacy