Results 271 to 280 of about 594,163 (347)

Sex Differences in Associations of Lewy Body Disease with Alzheimer's Disease and Cognitive Decline

Annals of Neurology, EarlyView.
Objective To investigate how sex and age at menopause influence the interplay between Alzheimer's disease (AD) and Lewy body disease (LBD) neuropathologies, and their associations with cognitive decline. Methods We analyzed data from: (1) three Rush Alzheimer's Disease Center cohorts (i.e., the Religious Orders Study, Rush Memory and Aging Project, and
Madeline Wood Alexander, D. Luke Fischer, Lawren VandeVrede, Emma Nichols, Lei Yu, James R. Pike, Walter Swardfager, Che‐Yuan Wu, Mario Masellis, Liisa A. M. Galea, Katherine Zukotynski, Gillian Einstein, Sandra E. Black, Lisa L. Barnes, Julie A. Schneider, Zoe Arvanitakis, Kaitlin B. Casaletto, Jennifer S. Rabin   +17 more
wiley   +1 more source

Cold aortic flush after ventricular fibrillation cardiac arrest reduces inflammatory reaction but not neuronal loss in the pig cerebral cortex. [PDF]

Sci Rep
Barones L, Weihs W, Schratter A, Janata A, Kodajova P, Bergmeister H, Kenner L, Holzer M, Behringer W, Högler S.   +9 more
europepmc   +1 more source

Volumetric MRI Comparing Longitudinal Change in MOGAD to NMOSD, MS and Healthy Controls, and Disability Associations

Annals of Neurology, EarlyView.
Objectives To examine volumetric magnetic resonance imaging (vMRI) in myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD), compared to multiple sclerosis (MS), neuromyelitis optica spectrum disorder (NMOSD), and healthy controls (HC). Methods Standardized vMRI in MOGAD were compared to age, sex, and disease duration matched MS (5:1),
Amy Kunchok, Moein Amin, Tatchaporn Ongphichetmetha, Mengke Du, Robert Bermel, Tucker Harvey, Justin R. Abbatemarco, Stephen E. Jones, Jeffrey A. Cohen, Daniel Ontaneda, Kunio Nakamura   +10 more
wiley   +1 more source

Spatiotemporal expression pattern of dyslexia susceptibility 1 candidate 1 (DYX1C1) during rat cerebral cortex development. [PDF]

Pediatr Res
Zensho K, Miyazaki I, Isse A, Misawa I, Masai K, Oka M, Tsukahara H, Asanuma M.   +7 more
europepmc   +1 more source

Exenatide Once Weekly in the Treatment of Patients with Multiple System Atrophy

Annals of Neurology, EarlyView.
Objective Exenatide, a glucagon‐like peptide‐1 (GLP‐1) receptor agonist, has neuroprotective effects in preclinical models of multiple system atrophy (MSA). We investigated these effects in a proof‐of‐concept clinical trial. Methods In this single‐center, randomized, open label trial, participants with MSA were randomly assigned (1:1) to receive ...
Nirosen Vijiaratnam, Christine Girges, Martin Wiegand, Claudia Ismail, Alexandra Lameirinhas, Alison Yarnall, Cameron Kirk, Silvia Del‐Din, Lynn Rochester, Christopher Kobylecki, Gareth Ambler, Simon Skene, Henry Houlden, Viorica Chelban, Amanda Heslegrave, Wendy Phillips, Alan Whone, Niall Quinn, Christian Lambert, Charlotte Dore, Huw R. Morris, Mathew H. Horrocks, Ji Eun Lee, Judi O'Shaughnessy, Yazhou Li, Nigel H. Greig, Sonia Gandhi, Vincenzo Libri, Dilan Athauda, Tom Foltynie   +29 more
wiley   +1 more source

The impact of metabolic syndrome on the cerebral cortex: a Mendelian randomization study. [PDF]

Cereb Cortex
Zhang P, Zhang X, Gao B, Gao Y, Pan Y.
europepmc   +1 more source

Intranasal Wharton's Jelly‐Derived Mesenchymal Stem Cell Therapy, Alone or in Conjunction With Therapeutic Hypothermia, Alleviates Neonatal Hypoxic‐Ischemic Brain Injury in Mice

Annals of Neurology, EarlyView.
This study demonstrates that intranasal Wharton's jelly‐derived mesenchymal stem cell (WJ‐MSC) administration at 3 or 10 days post‐insult reduced the lesion size and sensorimotor impairment following neonatal hypoxic‐ischemic (HI) brain injury in mice. WJ‐MSCs expressed receptors for HI‐upregulated chemokines and migrated from the nasal cavity into the
Caroline G. M. de Theije, Sara T. De Palma, Josine E. G. Vaes, Katiuscia Dallaglio, Giorgia Volpi, Diego Ardigò, Sabine van Rijt, Frank van Bel, Manon J. N. L. Benders, Cora H. A. Nijboer   +9 more
wiley   +1 more source

Treadmill Exercise Training Ameliorates Apoptotic Cells and DNA Oxidation in the Cerebral Cortex of Rats Exposed to Chronic Ketamine Abuse. [PDF]

Addict Biol
Sabziparvar S, Khodaei K, Azar JT.
europepmc   +1 more source

Biallelic Variants in the DARS2 Gene as a Novel Cause of Axonal Charcot–Marie–Tooth Disease

Annals of Neurology, EarlyView.
Objective Charcot–Marie–Tooth (CMT) disease is a heterogeneous group of genetic neuropathies, with >90 genes identified. Several aminoacyl‐tRNA synthetases have been linked to CMT. DARS2, encoding the mitochondrial aspartyl‐tRNA synthetase, has been typically associated with leukoencephalopathy with brainstem and spinal cord involvement and lactate ...
Berta Estévez‐Arias, Siiri Sarv, Nathalie Bonello‐Palot, Laura Carrera‐García, Carlos Ortez, Jesica Expósito‐Escudero, Delia Yubero, Jordi Muchart, Emilien Delmont, Eve Õiglane‐Shlik, Teele Meren, Sanna Puusepp, Ülle Murumets, Gajja S. Salomons, Bjarne Udd, Liis Väli, Lara Cantarero, Carsten G. Bönnemann, Andrés Nascimento, Santiago Ramón‐Maiques, Katrin Õunap, Janet Hoenicka, Daniel Natera‐de Benito, Francesc Palau   +23 more
wiley   +1 more source

Global Impact of Aging on the Hemodynamic Response Function in the Gray Matter of Human Cerebral Cortex. [PDF]

Hum Brain Mapp
Fesharaki NJ, Taylor A, Mosby K, Li R, Kim JH, Ress D.   +5 more
europepmc   +1 more source