Results 111 to 120 of about 1,314,540 (419)

High-Flow Vascular Malformations in Children. [PDF]

, 2020
Children can have a variety of intracranial vascular anomalies ranging from small and incidental with no clinical consequences to complex lesions that can cause substantial neurologic deficits, heart failure, or profoundly affect development. In contrast
Abla, Adib A, Braunstein, Steve, Cooke, Daniel L, Fullerton, Heather J, Gupta, Nalin, Hetts, Steven W, Kim, Helen, Morshed, Ramin A, Winkler, Ethan A   +8 more
core  

Bazedoxifene, a selective estrogen receptor modulator, reduces cerebral aneurysm rupture in Ovariectomized rats. [PDF]

, 2017
BackgroundEstrogen deficiency is thought to be responsible for the higher frequency of aneurysmal subarachnoid hemorrhage in post- than premenopausal women.
Hashimoto, Tomoki, Kitazato, Keiko T, Korai, Masaaki, Maekawa, Hidetsugu, Miyamoto, Takeshi, Nagahiro, Shinji, Satomi, Junichiro, Tada, Yoshiteru, Yagi, Kenji   +8 more
core   +1 more source

Microbleeds, Cerebral Hemorrhage, and Functional Outcome After Stroke Thrombolysis: Individual Patient Data Meta-Analysis

Stroke, 2017
Background and Purpose— We assessed whether the presence, number, and distribution of cerebral microbleeds (CMBs) on pre-intravenous thrombolysis MRI scans of acute ischemic stroke patients are associated with an increased risk of intracerebral ...
A. Charidimou, G. Turc, C. Oppenheim, Shenqiang Yan, J. Scheitz, H. Erdur, P. P. Klinger-Gratz, M. El-Koussy, W. Takahashi, Y. Moriya, D. Wilson, C. Kidwell, J. Saver, Asmaa Sallem, S. Moulin, M. Edjlali-Goujon, V. Thijs, Z. Fox, A. Shoamanesh, Gregory W. Albers, Heinrich P. Mattle, O. Benavente, H. R. Jäger, G. Ambler, Junya Aoki, J. Baron, K. Kimura, W. Kakuda, S. Takizawa, Simon Jung, Christian H. Nolte, M. Lou, C. Cordonnier, D. Werring   +33 more
semanticscholar   +1 more source

CXCL13 Damages Blood Spinal Cord Barrier by Promoting RNF6/Sqstm1‐Ubiquitination Induced Autophagy in Experimental Allergic Encephalomyelitis

Advanced Science, EarlyView.
In multiple sclerosis, the disruption of the blood‐spinal cord barrier (BSCB) induced by CXCL13 facilitates the infiltration of inflammatory cells into the central nervous system, resulting in demyelination and neuronal injury. Mechanistically, the deleterious impact of CXCL13 on the BSCB is associated with a reduction in tight junction protein ...
Jingjing Han, Rui Hong, Cong Cao, Wanhua Feng, Wei Zhuang, Gui Wang, Jingchao Tang, Ya Yang, Chu Zhang, Aihua Zhou, Xuebin Qu   +10 more
wiley   +1 more source

Expression of Sphingosine-1-phosphate (S1P) on the cerebral vasospasm after subarachnoid hemorrhage in rabbits [PDF]

Acta Cirúrgica Brasileira, 2015
PURPOSE: To demonstrate the relationship between of sphingosine-1-phosphate (S1P) expression and subarachnoid hemorrhage (SAH). METHODS: The basilar arteries from a "double-hemorrhage" rabbit model of SAH were used to investigate the relation between ...
Hua Tang, Donggang Zhao, Shaojun Chen, Ming Fang, Feifan Wang, Ying Cui, Na Tang, Qianxue Chen   +7 more
doaj   +1 more source

Neuronal C/EBPβ Shortens the Lifespan via Inactivating NAMPT

Advanced Science, EarlyView.
Schematic diagram illustrating the mechanism of shortened lifespan in Thy 1‐C/EBPβ transgenic mice and intervention strategies. Briefly, C/EBPβ/AEP escalation in the aging brain triggers NAMPT fragmentation and NAD+ depletion. Knockout of AEP from Thy 1‐C/EBPβ Tg/Tg mice ameliorates cognitive impairments and elongates the lifespan.
Bowei Li, Zhongyun Xie, Mengmeng Wang, Shuke Nie, Zhengjiang Qian, Xin Meng, Xia Liu, Seong Su Kang, Keqiang Ye   +8 more
wiley   +1 more source

Higher ventricular rate during atrial fibrillation relates to increased cerebral hypoperfusions and hypertensive events [PDF]

Scientific Reports, 9: 3779, 2019, 2019
Atrial fibrillation (AF) is associated with cognitive impairment/dementia, independently of clinical cerebrovascular events (stroke/TIA). One of the plausible mechanisms is the occurrence of AF-induced transient critical hemodynamic events; however, it is presently unknown, if ventricular response rate during AF may impact on cerebral hemodynamics.
arxiv   +1 more source

The Impact of Inter-Hospital Transfer on Clinical Outcomes following Endovascular Treatment for Acute Ischemic Stroke [PDF]

, 2019
PURPOSE Hospitals designated as primary stroke centers offer noninvasive treatment for acute ischemic stroke, but only comprehensive stroke centers are equipped to provide endovascular treatment.
Schmidt, Tyler
core   +1 more source

Rapid Blood Clot Removal via Remote Delamination and Magnetization of Clot Debris

Advanced Science, EarlyView.
A programmable colloidal microswarm is developed to quickly detach blood clots and enable rapid recanalization, with the detached debris functioning as a magnetic “debris‐robot” that can be efficiently propelled and retrieved via catheter suction, which could significantly save time compared to the critical “Golden 6 hours” window for ischemic stroke ...
Qinglong Wang, Ben Wang, Kai Fung Chan, Xin Song, Qianqian Wang, Fengtong Ji, Lin Su, Bonaventure Yiu Ming Ip, Ho Ko, Philip Wai Yan Chiu, Thomas Wai Hong Leung, Li Zhang   +11 more
wiley   +1 more source

The Experimental Study of Increased ICP on Cerebral Hemorrhage Rabbits with Magnetic Induction Phase Shift Method [PDF]

Iranian Journal of Medical Physics, 2016
Introduction Measuring magnetic induction phase shift (MIPS) changes as a function of cerebral hemorrhage volume has the potential for being a simple method for primary and non-contact detection of the occurrence and progress of cerebral hemorrhage.
Jian Sun, Gui Jin, Gen Li, Yujie Chen, Mingxin Qin   +4 more
doaj   +1 more source