Delivery strategies of messenger RNA therapeutics for brain disorders
Thus, mRNA therapeutics offer a powerful new avenue for the treatment of brain diseases. This review examines strategies to bypass biological barriers, particularly the blood–brain barrier, and explores emerging delivery systems, such as direct intracerebral injection, intracerebroventricular injection, systemic delivery (including intravenous ...
Kounghwa Youn +5 more
wiley +1 more source
The application of artificial airway care for postoperative weaning patients with cerebral hemorrhage by failure mode and effect analysis mode. [PDF]
Tang X +6 more
europepmc +1 more source
ABSTRACT Neurological disorders represent a critical domain within global health, necessitating advanced interventions to address complex pathologies such as tumors, functional disorders, and cerebrovascular diseases. Despite the proven benefits of early intervention, current treatment paradigms face significant challenges: (1) limited precision in ...
Qing Ye +14 more
wiley +1 more source
Prediction of Antibiotic Efficacy in Cerebral Hemorrhage-Associated Pneumonia Using Inflammatory Hematological Indices: A Retrospective Study. [PDF]
Wang X +5 more
europepmc +1 more source
A case of pseudoaldosteronism complicated by cerebral hemorrhage
Saori Okamoto +4 more
openalex +2 more sources
Cerebral Venous Thrombosis Presenting As Subarachnoid Hemorrhage: Clinical Case
Komi Ignéza Agbotsou +5 more
openalex +2 more sources
A Core Head, Neck, and Neuroanatomy Syllabus for Physical Therapy Student Education
ABSTRACT Head, neck, and neuroanatomy are essential components of physical therapy education due to their broad clinical applications. Detailed syllabi exist for medical students, yet none have been developed for physical therapy. This study aimed to produce an International Federation of Associations of Anatomists core head, neck, and neuroanatomy ...
Stephanie J. Woodley +4 more
wiley +1 more source
Cox health behavior intervention combined with psychological care for patients with hypertensive cerebral hemorrhage and mental disorders. [PDF]
Lu ND, Zhou JJ, Huang F.
europepmc +1 more source
Recurrent Cerebral Hemorrhage Associated with Ulcerative Colitis
Toshiyuki Yanagisawa +3 more
openalex +2 more sources
Abstract Background The prognosis for non‐small cell lung cancer (NSCLC) patients with extensive brain metastases (BMs) treated with radiotherapy alone remains poor. Based on the synergistic potential of radiotherapy and angiogenesis inhibitors, we initiated this phase II study to assess the efficacy and safety of combining bevacizumab (Bev) with ...
Rui Zhou +16 more
wiley +1 more source

