Platelets and acute cerebral infarction
Platelets, 2012 Stroke is worldwide a leading cause of death and disability. Its etiology is regarded as heterogeneous. Platelets are implicated in its pathophysiology, but our understanding of their specific role is incomplete. Only sparse and conflicting information exists about platelet reactivity and activity in acute stroke.
Järemo, Petter +4 more
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Elevating microRNA-122 in blood improves outcomes after temporary middle cerebral artery occlusion in rats. [PDF]
, 2016 Because our recent studies have demonstrated that miR-122 decreased in whole blood of patients and in whole blood of rats following ischemic stroke, we tested whether elevating blood miR-122 would improve stroke outcomes in rats.
Ander, Bradley P +9 more
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Post-ischaemic treatment with the cyclooxygenase-2 inhibitor nimesulide reduces blood-brain barrier disruption and leukocyte infiltration following transient focal cerebral ischaemia in rats [PDF]
Journal of Neurochemistry 100(4): 1108-1120 (2007), 2007 Several studies suggest that cyclooxygenase (COX)-2 plays a pivotal role in the progression of ischaemic brain damage. In the present study, we investigated the effects of selective inhibition of COX-2 with nimesulide (12 mg/kg) and selective inhibition of COX-1 with valeryl salicylate (VAS, 12-120 mg/kg) on prostaglandin E2 (PGE2) levels ...
arxiv
Dipyridamole plus aspirin versus aspirin alone in the secondary prevention after TIA or stroke: a meta-analysis by risk [PDF]
, 2008 Objectives: Our aim was to study the effect of combination therapy with aspirin and dipyridamole (A+D) over aspirin alone (ASA) in secondary prevention after transient ischemic attack or minor stroke of presumed arterial origin and to perform subgroup ...
A Algra +6 more
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Vascular Health and Risk Management, 2011 Halvor Naess, Fredrik RomiDepartment of Neurology, Haukeland University Hospital, N-5021 Bergen, NorwayBackground: To compare the clinical characteristics, and short-term outcome of spinal cord infarction and cerebral infarction.Methods: Risk factors ...
Naess H, Romi
doaj
Virtual monochromatic imaging in dual-source and dual-energy CT for visualization of acute ischemic stroke [PDF]
arXiv, 2015 We have recently developed a phantom that simulates acute ischemic stroke. We attempted to visualize acute-stage cerebral infarction by applying virtual monochromatic images to this phantom using dual-energy CT (DECT). Virtual monochromatic images were created using DECT from 40 to 100 keV at every 10 keV and from 60 to 80 keV at every 1 keV, under ...
arxiv
Inhibition of central angiotensin-converting enzyme with enalapril protects the brain from ischemia/reperfusion injury in normotensive rat [PDF]
Background and the Purpose of the study: Central Angiotensin Converting Enzyme (ACE) has an important role on cerebral microcirculation and metabolism.
دهقان, غلامعباس +1 more
core
Spontaneous showering of tumor emboli in a patient with advanced primary lung cancer: a case report [PDF]
, 2012 Extension of primary lung tumors into the left atrium via pulmonary veins is a well-documented phenomenon. Peripheral arterial embolism and cerebral embolism originating from a primary lung neoplasm are rare events. We report a case of simultaneous acute
Brian T Kloss +2 more
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Automatic Stroke Lesions Segmentation in Diffusion-Weighted MRI [PDF]
arXiv, 2018 Diffusion-Weighted Magnetic Resonance Imaging (DWI) is widely used for early cerebral infarct detection caused by ischemic stroke. Manual segmentation is done by a radiologist as a common clinical process, nonetheless, challenges of cerebral infarct segmentation come from low resolution and uncertain boundaries.
arxiv
Experimental Cerebral Infarction. II. Clinicopathological Model of Deep Cerebral Infarction [PDF]
Stroke, 1970 Injection of silicone rubber cylinders into the internal carotid system permits selective occlusion of the proximal middle cerebral artery segment in the dog. Occlusions of this segment obstruct the mouths of the lenticulostriate arteries and result in deep cerebral hemisphere infarctions. Surface vessels distal to the occluded segment remain
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