Results 51 to 60 of about 272,213 (359)
Wide therapeutic time window for nimesulide neuroprotection in a model of transient focal cerebral ischemia in the rat [PDF]
, 2004 Results from several studies indicate that cyclooxygenase-2 (COX-2) is involved ischemic brain injury. The purpose of this study was to evaluate the neuroprotective effects of the selective COX-2 inhibitor nimesulide on cerebral infarction and ...
Candelario-Jalil, Eduardo +4 more
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The prevention of cerebral infarction.
Nihon Naika Gakkai Zasshi, 1995 脳梗塞の予防の基本は,各個人が有する脳梗塞に対する危険因子を明らかにし,管理可能なものを管理することである.その多くは動脈硬化の進展を阻止することにつながる.危険因子には高血圧,糖尿病,心疾患,肥満,アルコール多飲,喫煙,脂質異常,年齢,性,経口避妊薬,高ヘマトクリット値,高ヘモグロビン値,高フィブリノーゲン血症,抗リン腸質抗体,薬物などがある.このうち,高血圧の管理が最も重要で,特に集団管理の重要性が注目されている。多くの危険因子の管理は生活様式の工夫,食事面の調整,薬物療法の組み合わせで行われる.抗血小板薬は脳梗塞の一次予防には有効ではない.しかし,抗血小板薬は脳梗塞の再発を,非使用例に比較して約25%減少させる.心原性脳塞栓の基礎疾患を有する患者に関しては抗凝血療法が重要である.
Fukuuchi Y, Tanahashi N
openaire +3 more sources
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Advanced Functional Materials, EarlyView.Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth +2 more
wiley +1 more source
Clinical risk factors predictive of thrombotic stroke with large cerebral infarction
Neurology International, 2019 Large cerebral infarctions have high morbidity and mortality. Patients with large cerebral infarctions may have recurrent ischemia as high as 8.1% within 7 days; highest among other types of strokes.
Worapot Rojsanga +5 more
doaj +1 more source
Brain Sciences, 2022 Objective: To investigate the angioarchitectural factors associated with postoperative cerebral infarction in ischemic moyamoya disease. Methods: Data on patients who underwent surgery for ischemic MMD from 1 October 2015 to 31 October 2020, at Peking ...
Tengfei Yu +5 more
doaj +1 more source
Contralateral cortical role on functional recovery in a rat model of hemiplegia [PDF]
, 2013 The role of the contralateral cerebral cortical plasticity in functional recovery after cerebral infarction is controversial. To clarify this role, we made a second contralateral cortical infarction after recovery from the first cerebral infarction.
Harada, Katsuhiro +4 more
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Advanced Healthcare Materials, EarlyView.The tissue and functional benefits are demonstrated with local, sustained delivery of an anti‐inflammatory peptide, pituitary adenylate cyclase‐activating polypeptide (PACAP), for stroke treatment in a mouse model. Prolonged PACAP treatment modulated astrocyte and microglia toward pro‐reparative phenotypes, enhanced neuroprotection and preservation of ...
Eric Ho +7 more
wiley +1 more source
NeuroImage: Clinical, 2022 Objectives: To investigate the value of diffusion weighted imaging (DWI) in predicting the clinical progression of perforator artery cerebral infarction.
Wenjing Yu +6 more
doaj
Rewiring Neuroimmunity: Nanoplatform Innovations for CNS Disease Therapy
Advanced Therapeutics, EarlyView.This review explores emerging nanoplatform strategies designed to modulate neuroimmune responses for treating central nervous system (CNS) disorders. It examines structural and microenvironmental barriers, advances in multifunctional and targeted nanotechnologies, and highlights clinical progress and translational challenges, offering insights into the
Muhammad Usman Akbar +7 more
wiley +1 more source
Commentary [Decompressive craniectomy in patients with cerebral infarction due to malignant vasospasm after aneurysmal subarachnoid hemorrhage] [PDF]
, 2012 Commentary: article "Decompressive craniectomy in patients with cerebral infarction due to malignant vasospasm after aneurysmal subarachnoid hemorrhage" on page 251 http://www.ncbi.nlm.nih.gov/pmc/articles ...
Archavlis, Eleftherios
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