Function of BID - a molecule of the bcl-2 family - in ischemic cell death in the brain [PDF]
, 2002 Mitochondrial mechanisms, particularly the release of cytochrome c, play a role in the death of nerve and glial cells in cerebral ischemia. We have currently investigated whether BID, a proapoptotic molecule of the bcl-2 family and promoter of the ...
Amin-Hanjani, Sepideh +5 more
core +1 more source
Small Vessel Disease in the Heart and Brain: Current Knowledge, Unmet Therapeutic Need and Future Directions [PDF]
, 2019 No abstract ...
Berry, C +6 more
core +2 more sources
Attenuation of Focal Cerebral Ischemic Injury Following Post Ischemic Inhibition of Angiotensin Converting Enzyme (ACE) Activity in Normotensive Rat [PDF]
Central renin angiotensin system has an important role on the cerebral microcirculation and metabolism. Our previous work showed that inhibition of angiotensin converting enzyme (ACE) activity prior to induction of ischemia protected the brain from ...
دهقان, غلامعباس +1 more
core +1 more source
Is elevated SUA associated with a worse outcome in young Chinese patients with acute cerebral ischemic stroke? [PDF]
, 2010 Background Elevated serum uric acid (SUA) levels can enhance its antioxidant prosperities and reduce the occurrence of cerebral infarction. Significantly elevated SUA levels have been associated with a better prognosis in patients with cerebral ...
A Chamorro +32 more
core +3 more sources
Clinical risk factors predictive of thrombotic stroke with large cerebral infarction
Neurology International, 2019 Large cerebral infarctions have high morbidity and mortality. Patients with large cerebral infarctions may have recurrent ischemia as high as 8.1% within 7 days; highest among other types of strokes.
Worapot Rojsanga +5 more
doaj +1 more source
Frontiers in Neurology, 2022 ObjectiveThe purpose of this study is to establish and evaluate an early biomarker prediction model of massive cerebral infarction caused by anterior circulation occlusion.MethodsOne hundred thirty-four patients with acute cerebral infarction from ...
Jingshu Chen +10 more
doaj +1 more source
Three dimensional simulations of embolic stroke: clinical comparisons and an equation for sizing emboli from imaging [PDF]
arXiv, 2021 There is a need to develop Monte Carlo simulations of stroke to run in-silico trials to replace animal models, explore clinical scenarios to develop hypotheses for clinical studies and for interpreting clinical monitoring. We perform three-dimensional (3D) stroke simulations, carrying out in-silico trials to relate lesion volume to embolus diameter and
arxiv
The prevention of cerebral infarction.
Nihon Naika Gakkai Zasshi, 1995 脳梗塞の予防の基本は,各個人が有する脳梗塞に対する危険因子を明らかにし,管理可能なものを管理することである.その多くは動脈硬化の進展を阻止することにつながる.危険因子には高血圧,糖尿病,心疾患,肥満,アルコール多飲,喫煙,脂質異常,年齢,性,経口避妊薬,高ヘマトクリット値,高ヘモグロビン値,高フィブリノーゲン血症,抗リン腸質抗体,薬物などがある.このうち,高血圧の管理が最も重要で,特に集団管理の重要性が注目されている。多くの危険因子の管理は生活様式の工夫,食事面の調整,薬物療法の組み合わせで行われる.抗血小板薬は脳梗塞の一次予防には有効ではない.しかし,抗血小板薬は脳梗塞の再発を,非使用例に比較して約25%減少させる.心原性脳塞栓の基礎疾患を有する患者に関しては抗凝血療法が重要である.
Fukuuchi Y, Tanahashi N
openaire +3 more sources
Contralateral cortical role on functional recovery in a rat model of hemiplegia [PDF]
, 2013 The role of the contralateral cerebral cortical plasticity in functional recovery after cerebral infarction is controversial. To clarify this role, we made a second contralateral cortical infarction after recovery from the first cerebral infarction.
Harada, Katsuhiro +4 more
core
NeuroImage: Clinical, 2022 Objectives: To investigate the value of diffusion weighted imaging (DWI) in predicting the clinical progression of perforator artery cerebral infarction.
Wenjing Yu +6 more
doaj