Results 61 to 70 of about 168 (168)

Pharmacological effects of gastrodin: Insight into neurological diseases and mechanism in ferroptosis and pyroptosis

open access: yesIbrain, Volume 11, Issue 1, Page 74-83, Spring 2025.
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley   +1 more source

Research progress of neurovascular units involved in ischemic stroke

open access: yesIbrain, EarlyView.
The brain receives less blood when an ischemic stroke develops, which damages neurons and leads to an increased release of Pro‐inflammatory mediators that activate neurovascular unit (NVU). When the tight junctions are broken and the basement membrane is disrupted by matrix metalloproteinases produced by active endothelial and pericellular cells ...
Yu Yang   +4 more
wiley   +1 more source

Neuroanatomical and functional correlates in borderline personality disorder: A narrative review

open access: yesIbrain, Volume 11, Issue 1, Page 19-31, Spring 2025.
Borderline personality disorder (BPD) is considered a dysfunctional, stable, and pervasive alteration in personality functioning with the inability to adapt to the environment, mental rigidity, and ego‐syntonic, and like all personality disorders is a consistent pattern of inner experience and behavior that deviates markedly from the expectations of ...
Giulio Perrotta
wiley   +1 more source

Vascular dysfunction in women with recurrent pregnancy loss: Possible association with antiphospholipid antibodies

open access: yesInternational Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 206-214, April 2025.
Abstract Objective Antiphospholipid antibodies (aPL) are recognized to have a pivotal role in recurrent pregnancy loss (RPL) and cardiovascular disease. Therefore, we assessed the vascular function of women with RPL and examined the association with each type of aPL.
Titi Yang   +11 more
wiley   +1 more source

Identification of crucial genes for polycystic ovary syndrome and atherosclerosis through comprehensive bioinformatics analysis and machine learning

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To identify potential biomarkers in patients with polycystic ovary syndrome (PCOS) and atherosclerosis, and to explore the common pathologic mechanisms between these two diseases in response to the increased risk of cardiovascular diseases in patients with PCOS.
Lirong Wang   +7 more
wiley   +1 more source

Chinese herbal medicine‐derived extracellular vesicle‐like particles: Therapeutic potential and future research approaches

open access: yesInterdisciplinary Medicine, EarlyView.
This article evaluates the therapeutic potential of extracellular vesicle‐like particles derived from Chinese herbal medicine (CHM‐EVLP) for a range of diseases. It underscores the significance of traditional Chinese medicine in the development of innovative formulations.
Ying‐qi Cao   +6 more
wiley   +1 more source

Mid‐Regional Proadrenomedullin Can Be Reliably Measured in Cerebrospinal Fluid to Improve Diagnosis of Central Nervous System Diseases

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Numerous evidences suggest that Adrenomedullin represents an important regulator of endothelial homeostasis also in the central nervous system and may have a role in infectious, inflammatory, and degenerative neurological diseases. Mid‐regional proadrenomedullin (MR‐proADM) can be reliably measured in cerebrospinal fluid using commercially available ...
Matteo Furlani   +7 more
wiley   +1 more source

Home‐based collaborative management of bullous pemphigoid with delayed seropositive conversion of anti‐BP180‐NC16a antibody

open access: yesJournal of General and Family Medicine, EarlyView.
We present the case of an elderly male with bullous pemphigoid, initially negative for the anti‐BP180‐NC16a antibody, which later became positive as disease activity progressed. The patient was successfully managed at home through multidisciplinary collaboration, including a general practitioner, dermatologist, nurses, and pharmacists.
Hiromitsu Yamashita   +3 more
wiley   +1 more source

The Diagnostic Value of Contrast‐Enhanced Vessel Wall MRI for Diagnosing Neuropsychiatric Systemic Lupus Erythematosus

open access: yesJournal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Imaging biomarkers for neuropsychiatric systemic lupus erythematosus (NPSLE) are highly needed, and intracranial contrast‐enhanced vessel wall imaging (CE‐VWI) can potentially detect cerebral vessel wall abnormalities in lupus. Purpose To evaluate the diagnostic value of CE‐VWI in differentiating NPSLE from non‐NPSLE.
Satoru Ide   +9 more
wiley   +1 more source

Pre‐operative transcranial Doppler ultrasound assessment of cerebral collateral circulation in children undergoing veno‐arterial extracorporeal membrane oxygenation or cardiac surgery

open access: yesJournal of Medical Radiation Sciences, EarlyView.
A pre‐cannulation survey of the circle of Willis (CoW) using transcranial Doppler (TCD) ultrasound was implemented to assess cerebral collateral circulation in children undergoing VA ECMO or cardiac surgery with cervical cannulation. The technique, in use since 2019, employs high‐end ultrasound platforms to assess brain morphology, haemorrhage and ...
Tristan Reddan   +3 more
wiley   +1 more source

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