Results 191 to 200 of about 1,149,621 (388)

Neuroprotective Effects of Exercise on Brain Edema and Neurological Movement Disorders Following the Cerebral Ischemia and Reperfusion in Rats

Basic and Clinical Neuroscience, 2017
Introduction: Cerebral ischemia and reperfusion causes physiological and biochemical changes in the neuronal cells that will eventually lead to cell damage.
Nabi Shamsaei, Soheila Erfani, Masoud Fereidoni, Ali Shahbazi   +3 more
doaj  

Cerebral Blood Flow and Neurologic Outcome When Nimodipine is Given after Complete Cerebral Ischemia in the Dog [PDF]

, 1984
Petter Andreas Steen, Leslie A. Newberg, James H. Milde, John D. Michenfelder   +3 more
openalex   +1 more source

Emerging Target Discovery Strategies Drive the Decoding of Therapeutic Power of Natural Products and Further Drug Development: A Case Study of Celastrol

Exploration, EarlyView.
Using celastrol as a case study, this review summarizes various target discovery strategies for natural products, including chemical proteomics, protein microarray, degradation‐based protein profiling, proteome‐wide label‐free approaches, network pharmacology, target‐based drug screening, and indirect strategies.
Yanbei Tu, Guiyu Dai, Yanyan Chen, Lihua Tan, Hanqing Liu, Meiwan Chen   +5 more
wiley   +1 more source

Engineered Exosome‐Based Senolytic Therapy Alleviates Stroke by Targeting p21+CD86+ Microglia

Exploration, EarlyView.
We identified a harmful immune cell type, p21+CD86+ microglia, driving post‐stroke inflammation and developed a targeted exosome‐based therapy (Que@micro‐Exo) to eliminate these cells. This innovative treatment reduced inflammation, alleviated brain damage, and improved recovery in stroke models, offering a promising strategy for stroke and other ...
Jialei Yang, Shipo Wu, Miao He
wiley   +1 more source

The Metabolic Effects of Mild Hypothermia on Global Cerebral Ischemia and Recirculation in the Cat: Comparison to Normothermia and Hyperthermia [PDF]

, 1989
Michael Chopp, Robert A. Knight, C D Tidwell, Joseph A. Helpern, Eileen Brown, K.M.A. Welch   +5 more
openalex   +1 more source

Exploring the Neuroprotective Role of Selenium: Implications and Perspectives for Central Nervous System Disorders

Exploration, EarlyView.
Selenium (Se) is a crucial element in selenoproteins, key biomolecules for physiological function in vivo. Central nervous system can express all 25 kinds of selenoproteins, which protect neurons by reducing oxidative stress and inflammatory response. Neuroprotection is being investigated through the biological study of Se.
Guanning Huang, Ying Liu, Xiadong Zhu, Lizhen He, Tianfeng Chen   +4 more
wiley   +1 more source

Cerebral ischemia detection using deep learning techniques. [PDF]

Health Inf Sci Syst
Pastor-Vargas R, Antón-Munárriz C, Haut JM, Robles-Gómez A, Paoletti ME, Benítez-Andrades JA.   +5 more
europepmc   +1 more source

A Study of Method for Enhancement of Perfusion Flow in Experimental Cerebral Ischemia

, 1978
Y Nakagawa, Y. Lucas Yamamoto, Ernest A. Meyer, Charles P. Hodge, William Feindel   +4 more
openalex   +2 more sources

A Comparison of the Cerebral Protective Effects of Isoflurane and Barbiturates during Temporary Focal Ischemia in Primates [PDF]

, 1987
Daniel G. Nehls, Michael M. Todd, Robert F. Spetzler, John C. Drummond, Richard A. Thompson, Peter C. Johnson   +5 more
openalex   +1 more source

Controlled Ascent Rate Enhances Autophagy and Mitigates Acute Lung Injury in Rats Exposed to High‐Altitude Hypoxia by Inhibiting Oxidative Stress and Inflammation

Global Challenges, EarlyView.
This study explores how gradual ascent rates reduce acute pulmonary injury in rats exposed to high‐altitude hypoxia by activating autophagy and suppressing oxidative stress and inflammation. Results show that controlled ascent effectively mitigates such injury, highlighting its potential as a preventive strategy.
Kairui Huang, Wenhui Shi, Jiajia Li, Xiaoyan Ma, Jiangwei Liu   +4 more
wiley   +1 more source