Results 191 to 200 of about 1,244,067 (429)

Clinical Relevance of ‘Cap’ and ‘Track’ Development after Recent Small Subcortical Infarct

open access: yesAnnals of Neurology, EarlyView.
Objective After a recent small subcortical infarct (RSSI), some patients develop perilesional or remote hyperintensities (‘caps/tracks’) to the index infarct on T2/FLAIR MRI. However, their clinical relevance remains unclear. We investigated the clinicoradiological correlates of ‘caps/tracks’, and their impact on long‐term outcomes following RSSI ...
Yajun Cheng   +24 more
wiley   +1 more source

Advancements in research on the immune-inflammatory mechanisms mediated by NLRP3 inflammasome in ischemic stroke and the regulatory role of natural plant products

open access: yesFrontiers in Pharmacology
Ischemic stroke (IS) is a major cause of mortality and disability among adults. Recanalization of blood vessels to facilitate timely reperfusion is the primary clinical approach; however, reperfusion itself may trigger cerebral ischemia-reperfusion ...
Kailin Yang   +7 more
doaj   +1 more source

A new pharmacological preconditioning-based target: from drosophila to kidney transplantation [PDF]

open access: yesarXiv, 2019
One of the biggest challenges in medicine is to dampen the pathophysiological stress induced by an episode of ischemia. Such stress, due to various pathological or clinical situations, follows a restriction in blood and oxygen supply to tissue, causing a shortage of oxygen and nutrients that are required for cellular metabolism.
arxiv  

The Role of Zinc in Cerebral Ischemia

open access: yesMolecular Medicine, 2007
Ischemic stroke is one of the most pervasive life-threatening neurological conditions for which there currently exists limited therapeutic intervention beyond prevention. As calcium-focused neuroprotective strategies have met with limited clinical success, it is imperative that alternative therapeutic targets be considered in the attempt to antagonize ...
Sherri L. Galasso, Richard H. Dyck
openaire   +3 more sources

Current Mechanistic Concepts in Ischemia and Reperfusion Injury

open access: yesCellular Physiology and Biochemistry, 2018
Ischemia-reperfusion injury is associated with serious clinical manifestations, including myocardial hibernation, acute heart failure, cerebral dysfunction, gastrointestinal dysfunction, systemic inflammatory response syndrome, and multiple organ ...
Meng-Yu Wu   +7 more
semanticscholar   +1 more source

A Newly Defined, Common Ophthalmologic Condition Requires Special Neurological Attention

open access: yesAnnals of Neurology, EarlyView.
A host of acquired abnormalities in visual function are known to occur in persons who suffer stroke, traumatic brain injury, and neurodegenerative disorders. Cerebral visual impairment occurs in children with early neurological injury or disorders, especially neonatal hypoxic‐ischemic injury.
Kristina K. Hardy   +2 more
wiley   +1 more source

Ability of Tong Luo Jiu Nao Oral Solution to Improve Cognitive and Gait Deficits in a Rat Model of Focal Cerebral Ischemia

open access: yesDigital Chinese Medicine, 2018
: Objective To investigate the ability of Tong Luo Jiu Nao (TLJN) Oral Solution to improve cognitive and gait deficits in a rat model of focal cerebral ischemia.Methods An intraluminal suture method was used to create a rat model of focal cerebral ...
Si-Di Li   +3 more
doaj  

Rule Based Expert System for Cerebral Palsy Diagnosis [PDF]

open access: yesarXiv, 2012
The use of Artificial Intelligence is finding prominence not only in core computer areas, but also in cross disciplinary areas including medical diagnosis. In this paper, we present a rule based Expert System used in diagnosis of Cerebral Palsy. The expert system takes user input and depending on the symptoms of the patient, diagnoses if the patient is
arxiv  

Roadmap to Nanomedical Applications: Nanotoxicology and In Vitro Guidelines for Lanthanide‐Doped Luminescence Nanothermometers

open access: yesAdvanced NanoBiomed Research, EarlyView.
Lanthanide‐based luminescence nanothermometry holds multifaceted potential for nanomedical applications, yet despite significant research advances, clinical translation of the engineered nanomaterials is still controversial and widely disputed. This is related to crucial nanotoxicological aspects that must be addressed at the preclinical level ...
Simona Premcheska   +2 more
wiley   +1 more source

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