Results 201 to 210 of about 355,372 (304)

Exploring the role of apolipoprotein ε4 in progressive myoclonic epilepsy type 1

Epileptic Disorders, EarlyView.
Abstract Objective Progressive myoclonic epilepsy type 1 (EPM1) is a neurodegenerative disease caused by biallelic variants in the cystatin B (CSTB) gene. Despite a progressive course, phenotype severity varies among patients, even within families. We studied the potential role of APOE ε4 in modifying phenotypic diversity in EPM1, given its established
Janina Gunnar, Yawu Liu, Henri Eronen, Tarja Joensuu, Marja Äikiä, Jelena Hyppönen, Katri Silvennoinen, Esa Mervaala, Juhana Hakumäki, Anna‐Elina Lehesjoki, Reetta Kälviäinen   +10 more
wiley   +1 more source

Administration of Ascorbic Acid Alleviates Neuronal Damage After Cerebral Ischemia in ODS Rats. [PDF]

Antioxidants (Basel)
Iwata N, Ogawa N, Imai T, Ridzuan SSB, Kamiuchi S, Matsuzaki H, Xuan M, Yuan B, Okazaki M, Hibino Y.   +9 more
europepmc   +1 more source

Neonatal seizures: Advances in diagnosis and management

Epilepsia Open, EarlyView.
Abstract The International League Against Epilepsy (ILAE) created the ILAE Neonatal Task Force that classified neonatal seizures, defined neonatal epilepsy syndromes, and specified treatment guidelines. These frameworks, in addition to improved access to genetic testing and other recent advances, have revolutionized the diagnosis and management of ...
Elissa G. Yozawitz, Ronit M. Pressler, Eli M. Mizrahi   +2 more
wiley   +1 more source

Targeting oxidative stress and metal imbalance in cerebral ischemia: the neuroprotective role of sodium valproate. [PDF]

Sci Rep
Ulaş M, Gökay Argadal Ö, Bardaş Özkan E.   +2 more
europepmc   +1 more source

Late‐onset epilepsy of unknown etiology is more treatment‐responsive than acquired lesional late‐onset epilepsy

Epilepsia Open, EarlyView.
Abstract Objective Late‐onset epilepsy of unknown etiology (LOEU) carries an elevated risk of dementia, suggesting that it may represent an early manifestation of neurodegenerative or cerebrovascular disease. Direct comparisons between LOEU and acquired lesional late‐onset epilepsy (LOE) may elucidate clinical features specific to LOEU.
L. Brian Hickman, Bhavya Pandey, Alexander Fish, Mohit Bandla, Adnan Husein, Corinne Allas, Harika Kottakota, Lauren Herzog, Keith Vossel, John M. Stern   +9 more
wiley   +1 more source

Morphometry of Intracranial Carotid Artery Calcifications in Patients with Recent Cerebral Ischemia. [PDF]

J Clin Med
Berghout BP, Fontana F, Huijben F, Korteland SA, Kooi ME, Nederkoorn PJ, de Jong PA, Gijsen FJ, Pirola S, Ikram MK, Bos D, Akyildiz AC.   +11 more
europepmc   +1 more source

The multiple hit model of infantile and epileptic spasms: The 2025 update

Epilepsia Open, EarlyView.
Abstract Objective Infantile and epileptic spasms syndrome (IESS) is a developmental and epileptic encephalopathy manifesting with epileptic spasms and poor neurodevelopmental outcomes. There is an urgent need for the development of more effective and tolerated therapies.
Aristea S. Galanopoulou, Wenzhu B. Mowrey, Wei Liu, Anna Maria Katsarou, Qianyun Li, Oleksii Shandra, Solomon L. Moshé   +6 more
wiley   +1 more source

Neuroprotective effect of riboflavin kinase on cerebral ischemia injury in rats. [PDF]

Mol Med
Zou Y, Ruan M, Feng X, Liu F, Liu W, Chen S, Chu Z.   +6 more
europepmc   +1 more source

Specifically Breaking Through the Injured Blood‐Brain Barrier With Tannic Acid‐Based Nanomedicine for Ischemic Stroke Ischemia Reperfusion Treatment

Exploration, EarlyView.
Protecting neuronal mitochondria by eliminating the mitochondrial ROS (mtROS) storm is crucial to abrogate the neuronal damage cascade of ischemic stroke ischemia reperfusion (ISIR), which is a long‐standing challenge in the field of ischemic stroke (IS).
Xiaojing Shi, Shuya Wang, Tingli Xiong, Ruishi Li, Wenxuan Zheng, Wensheng Chen, Tianjiao Zhao, Yongqi Yang, Xiaohong Ying, Weimin Qi, Yingci Xia, Jue Wang, Yuqi Zhang, Qiong Huang, Yayun Nan, Kelong Ai   +15 more
wiley   +1 more source

Cerebral Ischemia and Hemorheology [PDF]

Journal of Neurology, Neurosurgery & Psychiatry, 1988
openaire   +2 more sources