Abstract Background Parkinsonism in infancy is rare and is highly correlated with the presence of dystonia. Advances in treating and characterizing developmental and infantile degenerative parkinsonism have highlighted the need for a specialized assessment scale.
Roser Pons+16 more
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Adenosine A1 receptor agonist alleviates cerebral ischemia/reperfusion injury by inhibiting Nrf2/NLRP3 signaling‑mediated pyroptosis. [PDF]
Ming Q, Li Z, Tan J, Li Y.
europepmc +1 more source
(Poly)phenols constitute a source of natural therapeutic molecules capable of targeting angiogenesis in different scenarios. This review summarizes the current evidence of the role of (poly)phenols in modulating angiogenesis. The reader can find a compilation of preclinical and human investigations describing pro‐ and anti‐angiogenic effects of these ...
María Ángeles Ávila‐Gálvez+5 more
wiley +1 more source
Electroacupuncture protects against cerebral ischemia-reperfusion injury via regulating P2×7R expression. [PDF]
Chen S+9 more
europepmc +1 more source
Segmentation‐assisted vessel centerline extraction from cerebral CT Angiography
Abstract Background The accurate automated extraction of brain vessel centerlines from Computed tomographic angiography (CTA) images plays an important role in diagnosing and treating cerebrovascular diseases such as stroke. Despite its significance, this task is complicated by the complex cerebrovascular structure and heterogeneous imaging quality ...
Sijie Liu+7 more
wiley +1 more source
SIRT1 Alleviates Mitochondrial Fission and Necroptosis in Cerebral Ischemia/Reperfusion Injury via SIRT1-RIP1 Signaling Pathway. [PDF]
Wei X+8 more
europepmc +1 more source
The role of gut microbiota‐derived metabolites in neuroinflammation
Gut microbiota‐derived metabolites accumulate in the brain, activating or inhibiting microglia and astrocytes, which affects neuroinflammatory progression. The gut microbiota converts the diet into a variety of metabolites, including bile acid, trimethylamine N‑oxide (TMAO), and indole.
Lingjie Mu, Yijie Wang
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ZD7288 ameliorates long-term cerebral ischemia reperfusion-induced deterioration of spatial memory by regulating the expressions of NMDA receptor subunits in rats. [PDF]
He Z+8 more
europepmc +1 more source
History of pre‐eclampsia negatively impacts stroke severity postpartum in rats
Diagrammatic representation of the effect of pre‐eclampsia on postpartum stroke severity. e7, gestational day 7; ePE, experimental pre‐eclampsia; NormP, normal pregnancy; PP, postpartum; tMCAO, transient middle cerebral artery occlusion. Made in Biorender.
Ari Kropf+4 more
wiley +1 more source