Results 331 to 340 of about 1,149,621 (388)
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Cerebral Ischemia and Angiogenesis
Current Neurovascular Research, 2006Angiogenesis occurs in a wide range of conditions. As ischemic tissue usually depends on collateral blood flow from newly produced vessels, acceleration of angiogenesis should be of therapeutic value to ischemic disorders. Indeed, therapeutic angiogenesis reduced tissue injury in myocardial or limb ischemia.
Atsushi Tsuchiya+6 more
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Polyamines in cerebral ischemia
Neurochemical Pathology, 1988The present series of experiments was designed to study regional profiles of polyamines (putrescine, spermidine, and spermine) in reversible cerebral ischemia produced in rats and Mongolian gerbils. Polyamine profiles did not change during ischemia, but did following recirculation.
Joachim Hallmayer+3 more
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Microvascular Research, 1977
Abstract Total cerebral ischemia often injures or alters the microcirculation. This injury is highly variable within microregions, often resulting in different patterns of reperfusion within 100 μm. There is a growing consensus that the microcirculation injury is a consequence of ischemic brain injury rather than an essential pathogenetic step to it.
Wilhelm Erdmann+3 more
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Abstract Total cerebral ischemia often injures or alters the microcirculation. This injury is highly variable within microregions, often resulting in different patterns of reperfusion within 100 μm. There is a growing consensus that the microcirculation injury is a consequence of ischemic brain injury rather than an essential pathogenetic step to it.
Wilhelm Erdmann+3 more
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Cerebral ischemia and inflammation
Current Opinion in Neurology, 2001Cerebral ischemia is accompanied by a marked inflammatory reaction that is initiated by ischemia-induced expression of cytokines, adhesion molecules, and other inflammatory mediators, including prostanoids and nitric oxide. Preclinical studies suggest that interventions that are aimed at attenuating such inflammation reduce the progression of brain ...
Costantino Iadecola, Mihaela Alexander
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JAMA, 1961
Because of the sensitivity of the brain to hypoxia, acute cerebral ischemia due to operative or postoperative disruption of circulatory homeostasis, especially in older persons, should not be surprising. Six cases were selected to illustrate various peripheral circulatory mechanisms which, in conjunction with unrecognized preexisting cerebral vascular ...
Joseph F. Fazekas+5 more
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Because of the sensitivity of the brain to hypoxia, acute cerebral ischemia due to operative or postoperative disruption of circulatory homeostasis, especially in older persons, should not be surprising. Six cases were selected to illustrate various peripheral circulatory mechanisms which, in conjunction with unrecognized preexisting cerebral vascular ...
Joseph F. Fazekas+5 more
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Archives of Surgery, 1970
Eighteen of twenty patients with subclavian or innominate artery obstruction experienced episodes of transient cerebral arterial insufficiency; one patient suffered acute stroke and coma; all patients had angiographic evidence of subclavian or innominate artery obstruction; and most were shown to have retrograde flow in a vertebral artery. Two clinical
Theodore Drapanas+2 more
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Eighteen of twenty patients with subclavian or innominate artery obstruction experienced episodes of transient cerebral arterial insufficiency; one patient suffered acute stroke and coma; all patients had angiographic evidence of subclavian or innominate artery obstruction; and most were shown to have retrograde flow in a vertebral artery. Two clinical
Theodore Drapanas+2 more
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Hemichannels in Cerebral Ischemia
Current Molecular Medicine, 2009Hemichannels are transmembrane channels that represent the functional subunits of gap junctions. Each hemichannel is composed of a connexin or pannexin hexamer and, after being transported to the membrane, remains unpaired until it is incorporated in a gap junction. Several studies have already provided evidence that gap junction-mediated intercellular
Markus Schwaninger+2 more
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2011
Rodent models of focal cerebral ischemia have been extremely useful in elucidating pathomechanisms of human stroke. Most commonly, a monofilament is advanced through the internal carotid artery of rodents to occlude the origin of the middle cerebral artery thus leading to critical ischemia in the corresponding vascular territory.
Guido Stoll+3 more
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Rodent models of focal cerebral ischemia have been extremely useful in elucidating pathomechanisms of human stroke. Most commonly, a monofilament is advanced through the internal carotid artery of rodents to occlude the origin of the middle cerebral artery thus leading to critical ischemia in the corresponding vascular territory.
Guido Stoll+3 more
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Cell Death Mechanisms in Cerebral Ischemia–Reperfusion Injury
Neurochemical Research, 2022Qian-ru Zhang+4 more
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Focal Cerebral Ischemia and Migraine
Cephalalgia, 1985Consistent literature data on the cerebrovascular risk in migraineous patients are lacking. Available preliminary clinical data (Italian Cooperative Cross-Sectional Case-Control Study) suggest that migraine can hardly be considered a relevant pathogenetic associated risk factor of focal cerebral ischemia.
PRENCIPE M+3 more
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