Results 221 to 230 of about 1,645,602 (269)
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Human cerebral malaria: 2019 mini review
Revue Neurologique, 2019During severe malaria, both in endemic and non-endemic areas, cerebral malaria is strongly associated with mortality and morbidity. The main mechanisms of cerebral malaria combine sequestration of parasitized red blood cells in brain capillaries ...
F Bruneel
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Nano letters (Print), 2021
Human malaria is a global life-threatening infectious disease. Cerebral malaria (CM) induced by Plasmodium falciparum parasites accounts for 90% of malaria deaths. Treating CM is challenging due to inadequate treatment options and the development of drug
Wei Wei +13 more
semanticscholar +1 more source
Human malaria is a global life-threatening infectious disease. Cerebral malaria (CM) induced by Plasmodium falciparum parasites accounts for 90% of malaria deaths. Treating CM is challenging due to inadequate treatment options and the development of drug
Wei Wei +13 more
semanticscholar +1 more source
Current Tropical Medicine Reports, 2021
Malaria is the most important parasitic disease of humankind. Cerebral malaria is malaria’s deadliest clinical manifestation and has a profound public health impact in endemic areas. In Africa, it is primarily a disease of childhood. Here we review recent updates in research into cerebral malaria pathogenesis, clinical care, treatment, and prevention ...
Geoffrey Guenther +3 more
openaire +2 more sources
Malaria is the most important parasitic disease of humankind. Cerebral malaria is malaria’s deadliest clinical manifestation and has a profound public health impact in endemic areas. In Africa, it is primarily a disease of childhood. Here we review recent updates in research into cerebral malaria pathogenesis, clinical care, treatment, and prevention ...
Geoffrey Guenther +3 more
openaire +2 more sources
Journal of the American College of Emergency Physicians, 1977
Cerebral malaria is an unusual and treatable cause of stupor and coma, and it can present suddenly in a healthy person. It is diagnosed by finding parasites on a blood smear and is treated either with chloroquine or with quinine, pyrimethamine, and sulfadiazine.
A C, Broders, H, Dhingra
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Cerebral malaria is an unusual and treatable cause of stupor and coma, and it can present suddenly in a healthy person. It is diagnosed by finding parasites on a blood smear and is treated either with chloroquine or with quinine, pyrimethamine, and sulfadiazine.
A C, Broders, H, Dhingra
openaire +2 more sources
Seminars in Pediatric Neurology
Cerebral malaria is the most lethal form of Plasmodium falciparum infection. The disease is defined clinically as an otherwise unexplained coma in someone with malaria parasitemia. One in 6 children with cerebral malaria dies and many survivors are left with neurologic, cognitive, or behavioral sequelae. Acute seizures are common and increasing numbers
Douglas G. Postels +1 more
openaire +3 more sources
Cerebral malaria is the most lethal form of Plasmodium falciparum infection. The disease is defined clinically as an otherwise unexplained coma in someone with malaria parasitemia. One in 6 children with cerebral malaria dies and many survivors are left with neurologic, cognitive, or behavioral sequelae. Acute seizures are common and increasing numbers
Douglas G. Postels +1 more
openaire +3 more sources
Fenozyme Protects the Integrity of Blood Brain Barrier against Experimental Cerebral Malaria.
Nano letters (Print), 2019Cerebral malaria is a lethal complication of malaria infection characterized by central nervous system dysfunction, and is often not effectively treated by the anti-malaria combination therapies.
Shuai Zhao +4 more
semanticscholar +1 more source
2013
Malaria, the most significant parasitic disease of man, kills approximately one million people per year. Half of these deaths occur in those with cerebral malaria (CM). The World Health Organization (WHO) defines CM as an otherwise unexplained coma in a patient with malarial parasitemia.
Douglas G, Postels, Gretchen L, Birbeck
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Malaria, the most significant parasitic disease of man, kills approximately one million people per year. Half of these deaths occur in those with cerebral malaria (CM). The World Health Organization (WHO) defines CM as an otherwise unexplained coma in a patient with malarial parasitemia.
Douglas G, Postels, Gretchen L, Birbeck
openaire +2 more sources
Epilepsia, 2008
SummaryMalaria, one of the most common parasitic diseases worldwide, is responsible for more than one million deaths among African children every year. Its neurological form, known as cerebral malaria (CM) is a potential cause of epilepsy in malaria‐endemic regions of the world, primarily made up for the most part by the sub‐Saharan Africa.
Pierre-Marie Preux
exaly +4 more sources
SummaryMalaria, one of the most common parasitic diseases worldwide, is responsible for more than one million deaths among African children every year. Its neurological form, known as cerebral malaria (CM) is a potential cause of epilepsy in malaria‐endemic regions of the world, primarily made up for the most part by the sub‐Saharan Africa.
Pierre-Marie Preux
exaly +4 more sources
Archives of Neurology, 1978
Neuropathologic examination of 19 fatal cases of cerebral malaria and a review of the literature showed that the epidemiologic, clinical, and pathologic features of this entity suggest consideration of cerebral malaria as a form of disseminated vasculomyelinopathy, a hyperegic reaction of the CNS to the antigenic challenge of Plasmodium falciparum ...
G, Toro, G, Román
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Neuropathologic examination of 19 fatal cases of cerebral malaria and a review of the literature showed that the epidemiologic, clinical, and pathologic features of this entity suggest consideration of cerebral malaria as a form of disseminated vasculomyelinopathy, a hyperegic reaction of the CNS to the antigenic challenge of Plasmodium falciparum ...
G, Toro, G, Román
openaire +2 more sources
Cerebral malaria and immunogenetics
Parasite Immunology, 2000Cerebral malaria depends largely on the capacity of Plasmodium falciparum infected red blood cells to adhere to the endothelia of microvessels, leading to their occlusion. The most important players include receptors expressed on the surface of the endothelial cell and known to interact with the parasite, cytokines modulating the expression of these ...
D, Mazier, J, Nitcheu, M, Idrissa-Boubou
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