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Severe malaria

Malaria Journal, 2022
Severe malaria is a medical emergency. It is a major cause of preventable childhood death in tropical countries. Severe malaria justifies considerable global investment in malaria control and elimination yet, increasingly, international agencies, funders
Nicholas J. White
doaj   +4 more sources

Gut bacterial dysbiosis in pediatric severe malaria associates with post-discharge mortality [PDF]

Nature Communications
Gut microbiota have been implicated in severe malaria in murine models, but their contribution to the pathogenesis of severe malaria in children is unknown.
Olivia J. Bednarski, Sawyer B. Lehman, David Mzinza, Caroline Kazinga, Ruth Namazzi, Robert O. Opoka, Jie Ren, Tuan M. Tran, Terrie E. Taylor, Karl B. Seydel, Chandy C. John, Andrea L. Conroy, Nathan W. Schmidt   +12 more
doaj   +2 more sources

Severe malaria in children and adolescents in Southeast Gabon

BMC Infectious Diseases, 2023
Introduction Malaria remains a significant public health problem in sub-Saharan Africa. Child mortality due to severe malaria remains high in developing countries despite improvements in malaria management and a better understanding of its ...
Judicaël Boris Lendongo Wombo, Euloge Ibinga, Sandrine Lydie Oyegue-Liabagui, Roméo Karl Imboumy Limoukou, Alain Prince Okouga, Franck Mounioko, Sydney Maghendji-Nzondo, Jean Bernard Lekana-Douki, Edgard Brice Ngoungou   +8 more
doaj   +1 more source

Malaria Related Neurocognitive Deficits and Behavioral Alterations

Frontiers in Cellular and Infection Microbiology, 2022
Typical of tropical and subtropical regions, malaria is caused by protozoa of the genus Plasmodium and is, still today, despite all efforts and advances in controlling the disease, a major issue of public health. Its clinical course can present either as
Pamela Rosa-Gonçalves, Pamela Rosa-Gonçalves, Pamela Rosa-Gonçalves, Flávia Lima Ribeiro-Gomes, Flávia Lima Ribeiro-Gomes, Cláudio Tadeu Daniel-Ribeiro, Cláudio Tadeu Daniel-Ribeiro   +6 more
doaj   +1 more source

Shifts in the clinical epidemiology of severe malaria after scaling up control strategies in Mali

Frontiers in Neurology, 2022
A decrease in malaria incidence following implementation of control strategies such as use of artemisinin-based combination therapies, insecticide-impregnated nets, intermittent preventive treatment during pregnancy and seasonal malaria chemoprevention ...
Drissa Coulibaly, Abdoulaye K. Kone, Bourama Kane, Bouréima Guindo, Bourama Tangara, Mody Sissoko, Fayçal Maiga, Karim Traore, Aichatou Diawara, Amidou Traore, Ali Thera, Mahamadou S. Sissoko, Ogobara K. Doumbo, Mark A. Travassos, Mahamadou A. Thera   +14 more
doaj   +1 more source

A Comparative Study of Clinical Profiles of Vivax and Falciparum Malaria in Children at a Tertiary Care Centre in Uttarakhand [PDF]

Journal of Clinical and Diagnostic Research, 2013
Background: Falciparum malaria has been constantly associated with high morbidity and mortality for a long time. Vivax malaria, which was once thought to be a relatively benign condition, is appearing in its more malignant form, with severity ...
Ragini Singh, Shruti Kumar, S.K. Rana, Brijesh Thakur, S.P. Singh   +4 more
doaj   +1 more source

Treating severe malaria [PDF]

BMJ, 2005
Rectal artemether may be as good as intravenous quinine E very year over a million children die of malaria in Africa. In many settings, especially rural ones, most fatalities due to malaria occur outside hospital, although a substantial proportion of these children will have made contact with some level of healthcare in their final illness.1 Of those
Whitty, Christopher JM, Ansah, Evelyn, Reyburn, Hugh   +2 more
openaire   +3 more sources

NCR3 polymorphism, haematological parameters, and severe malaria in Senegalese patients [PDF]

PeerJ, 2018
Background Host factors, including host genetic variation, have been shown to influence the outcome of Plasmodium falciparum infection. Genome-wide linkage studies have mapped mild malaria resistance genes on chromosome 6p21, whereas NCR3-412 ...
Alassane Thiam, Sabrina Baaklini, Babacar Mbengue, Samia Nisar, Maryam Diarra, Sandrine Marquet, Mouhamadou Mansour Fall, Michel Sanka, Fatou Thiam, Rokhaya Ndiaye Diallo, Magali Torres, Alioune Dieye, Pascal Rihet   +12 more
doaj   +2 more sources

Malaria Hepatopathy and Thrombocytopenia in Severe Falciparum Malaria

The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy, 2023
Jaundice commonly occurs in severe malaria, seen in approximately 2,5% patients with falciparum malaria infection. Jaundice in malaria can be caused by intravascular hemolysis, disseminated intravascular coagulation (DIC) or malaria-related liver ...
Muhammad Vitanata Arfijanto, Mohammad Imam Wahyudi   +1 more
doaj   +1 more source

BIOMARKERS AND PROGNOSTIC SCORING IN CEREBRAL MALARIA

Malang Neurology Journal, 2022
Malaria remains a public health concern and remain the deadliest in infectious disease in the world. Cerebral malaria is a particularly severe complication of this disease and associated with high mortality.
Orlando Pikatan, Ellen Ferlita Tirtana, Kezia Seraphine, Wienta Diarsvitri   +3 more
doaj   +1 more source