Results 21 to 30 of about 1,804,243 (315)
Improving statistical power in severe malaria genetic association studies by augmenting phenotypic precision
eLife, 2021 Severe falciparum malaria has substantially affected human evolution. Genetic association studies of patients with clinically defined severe malaria and matched population controls have helped characterise human genetic susceptibility to severe malaria ...James A Watson, Carolyne M Ndila, Sophie Uyoga, Alexander Macharia, Gideon Nyutu, Shebe Mohammed, Caroline Ngetsa, Neema Mturi, Norbert Peshu, Benjamin Tsofa, Kirk Rockett, Stije Leopold, Hugh Kingston, Elizabeth C George, Kathryn Maitland, Nicholas PJ Day, Arjen M Dondorp, Philip Bejon, Thomas N Williams, Chris C Holmes, Nicholas J White +20 moredoaj +1 more sourceAge patterns of severe paediatric malaria and their relationship to Plasmodium falciparum transmission intensity. [PDF]
, 2009 BACKGROUND: The understanding of the epidemiology of severe malaria in African children remains incomplete across the spectrum of Plasmodium falciparum transmission intensities through which communities might expect to transition, as intervention ...Abdullah Al-Taiar, Idro, Richard, Okiro Emelda A, Berkley, James, Al-Taiar Abdullah, Berkley James A, Berkley, James A, Snow, Robert, Al-Taiar, Abdullah, Berkley, JA, Emelda A Okiro, Okiro, EA, James A Berkley, Snow, Robert W, Okiro, Emelda A, Idro, R, Snow, RW, Robert W Snow, Snow Robert W, Reyburn, H, Hugh Reyburn, Richard Idro, Reyburn Hugh, Al-Taiar, A, Reyburn, Hugh, Idro Richard +25 morecore +1 more sourceCandidate polymorphisms and severe malaria in a Malian population. [PDF]
, 2012 Malaria is a major health burden in sub-Saharan African countries, including Mali. The disease is complex, with multiple genetic determinants influencing the observed variation in response to infection, progression, and severity.Belco Poudiougou, Toure, Ousmane, Sall, Abdourahmane H, Kirk A Rockett, Ogobara Doumbo, Sissoko Sibiri, Diarra Elisabeth, Amadou Niangaly, Konate Salimata, Barry, Abdoulaye, Taane G Clark, Taane G. Clark (106263), Sibiri Sissoko, Poudiougou Belco, Sall Abdourahmane H., Thera, Mahamadou A, Ousmane Toure (22538), Collaboration with The MalariaGEN Consortium, Mahamadou A Thera, Abdourahmane H Sall, Nuno Sepulveda, Poudiougou, Belco, Clark, Taane G, Sibiri Sissoko (138104), Thera Mahamadou A., Elisabeth Diarra (138119), Salimata Konate (138100), Campino Susana, Doumbo Ogobara, Diarra, Elisabeth, Nuno Sepulveda (124822), Ousmane Toure, Susana Campino, Kirk A. Rockett (138127), Rockett, Kirk A, Abdourahmane H. Sall (138114), Toure Ousmane, Amadou Niangaly (83858), Ogobara Doumbo (35290), Barry Abdoulaye, Campino, Susana, Susana Campino (56411), Rockett Kirk A., Abdoulaye Barry (138109), Clark Taane G., Sepulveda, Nuno, Elisabeth Diarra, Konate, Salimata, Abdoulaye Barry, Belco Poudiougou (22535), Mahamadou A. Thera (35284), Sepulveda Nuno, Niangaly, Amadou, Salimata Konate, Niangaly Amadou, Sissoko, Sibiri, Doumbo, Ogobara +56 morecore +2 more sourcesIncreased interferon-γ levels and risk of severe malaria: a meta-analysis
Scientific Reports, 2022 Interferon (IFN)-γ contributes to the pathogenesis of severe malaria; however, its mechanism remains unclear. Herein, differences in IFN-γ levels between patients with severe and uncomplicated malaria were evaluated using qualitative and quantitative ...Aongart Mahittikorn, Wanida Mala, Frederick Ramirez Masangkay, Kwuntida Uthaisar Kotepui, Polrat Wilairatana, Manas Kotepui +5 moredoaj +1 more sourceDiagnosing Severe Falciparum Malaria in Parasitaemic African Children: A Prospective Evaluation of Plasma PfHRP2 Measurement. [PDF]
, 2012 In African children, distinguishing severe falciparum malaria from other severe febrile illnesses with coincidental Plasmodium falciparum parasitaemia is a major challenge. P. falciparum histidine-rich protein 2 (PfHRP2) is released by mature sequestered Pan-Ngum Wirichada, George Mtove (124816), Gesase Samwel, Woodrow, Charles, Saiwaew, Somporn, Mwanga-Amumpaire Juliet, Fanello, CI, Kathryn Maitland, Ermelinda Gomes, Sarah Joseph (140503), White, Lisa, Nicholas J. White (35779), Ilse C E Hendriksen, Arjen M Dondorp, Gomes, Ermelinda, Samwel Gesase, Charles Woodrow, Sue J. Lee (140486), Rasaq Olaosebikan, Kesinee Chotivanich (140505), Fanello, Caterina I, Nicholas J White, Hendriksen Ilse C. E., White Nicholas J., von Seidlein Lorenz, Tshefu, Antoinette K, Antoinette K. Tshefu (140488), Sarah Joseph, von Seidlein, Lorenz, Antoinette K Tshefu, Lee, Sue, Silamut, Kamolrat, Tshefu Antoinette K., Woodrow, C, Corine Karema (140493), Ilse C. E. Hendriksen (140479), Mwanga-Amumpaire, J, Day Nicholas P. J., White Lisa J., White, Nicholas J, Caterina I. Fanello (140506), Maitland, K, Lee Sue J., Nicholas P J Day, Dondorp, Arjen M, Kamolrat Silamut (140501), Maitland Kathryn, Woodrow Charles, Dondorp, Adrianus, Arjen M. Dondorp (140509), Reyburn, Hugh, Day, Nicholas P J, Tshefu, AK, Day, Nicholas, Sue J Lee, Corine Karema, Juliet Mwanga-Amumpaire (140482), White, NJ, Lorenz von Seidlein (45473), Amos Ben, White, Lisa J, Lisa J White, Maitland, Kathryn, Amos, Ben, Somporn Saiwaew (140495), Silamut Kamolrat, Olaosebikan, Rasaq, Gomes, E, Lorenz von Seidlein, Pan-Ngum, W, Mtove, G, Samwel Gesase (140499), Hendriksen, ICE, Wirichada Pan-Ngum (2583205), Nicholas P. J. Day (35781), George Mtove, Joseph, Sarah, Gesase, Samwel, Hendriksen, IC, Chotivanich Kesinee, Saiwaew, S, Lisa J. White (101780), Hendriksen, Ilse C E, von Seidlein, L, Fanello Caterina I., Hugh Reyburn (45198), Reyburn Hugh, Juliet Mwanga-Amumpaire, Charles Woodrow (140489), Hendriksen, AM, Ben Amos (140491), Lee, Sue J, Gomes Ermelinda, Chotivanich, Kesinee, Wirichada Pan-Ngum, White, Nicholas, White, LJ, Ben Amos, Dondorp, AM, Gesase, S, Pan-Ngum, Wirichada, Mwanga-Amumpaire, Juliet, Amos, B, Karema, C, Day, NP, Joseph, S, Day, NPJ, Karema Corine, Saiwaew Somporn, Joseph Sarah, Karema, Corine, Lee, SJ, Chotivanich, K, Ermelinda Gomes (140497), Somporn Saiwaew, Kamolrat Silamut, Reyburn, H, Hugh Reyburn, Kesinee Chotivanich, Rasaq Olaosebikan (130780), Olaosebikan Rasaq, Kathryn Maitland (21356), Dondorp Arjen M., Silamut, K, Mtove George, Olaosebikan, R, Mtove, George, Caterina I Fanello +127 morecore +1 more sourceThe treatment of severe malaria
Transactions of the Royal Society of Tropical Medicine and Hygiene, 2007 In the SEAQUAMAT trial, parenteral artesunate was shown to be associated with a considerably lower mortality than quinine, and is now the recommended treatment for severe malaria in low-transmission areas and in the second and third trimesters of pregnancy. A trial is underway to establish its role in African children.Dondorp, A, Day, Nopenaire +3 more sourcesSevere malaria - a case of fatal Plasmodium knowlesi infection with post-mortem findings: a case report. [PDF]
, 2010 BACKGROUND: Zoonotic malaria caused by Plasmodium knowlesi is an important, but newly recognized, human pathogen. For the first time, post-mortem findings from a fatal case of knowlesi malaria are reported here.Hiu, Jessie, Mohammad, Zulkarnaen, Patricia Chandran, Zulkarnaen Mohammad, Adem, P, Paul C Divis, Singh Balbir, Lucas, S.B., Patricia, Adem, Balbir, Singh, Singh, Balbir, Janet Cox-Singh, Singh, B, Balbir Singh, Janet, Cox-Singh, Divis, P.C., Divis Paul C, Kum T, Wong, Chandran, Patricia, Wong Kum T, Paul C, Divis, Sanjeev, Krishna, Wong, Kum T., Zaki, Sherif R., Krishna, S., Chandran Patricia, Kum T Wong, Sanjeev Krishna, Jessie Hiu, Zaki Sherif R, Patricia, Chandran, Singh, B., Sherif R Zaki, Jessie, Hiu, Hiu, J, Chandran, P., Wong, K.T., Wong, KT, Cox-Singh, J, Adem, Patricia, Zulkarnaen, M, Divis, Paul C., Zulkarnaen, Mohammad, Sherif R, Zaki, Lucas Sebastian B, Cox-Singh Janet, Krishna Sanjeev, Mohammad Zulkarnaen, Lucas, Sebastian B., Sebastian B Lucas, Zaki, SR, Cox Singh, Janet, Cox-Singh, J., Krishna, S, Adem Patricia, Chandran, P, Krishna, Sanjeev, Adem, P., Hiu Jessie, Zulkarnaen, M., Patricia Adem, Zaki, S.R., Divis, PC, Lucas, SB, Hiu, J., Sebastian B, Lucas +65 morecore +1 more sourcePreparedness for severe malaria
Tidsskrift for Den norske legeforening, 2015 About 60 patients with malaria are admitted to Norwegian hospitals every year. The prescription figures for malaria medication may suggest that Norwegians are increasingly exposed to malaria infection.All Norwegian hospitals with a department of internal medicine were sent an electronic questionnaire for reporting the available methods for diagnosing ...Åsmund, Heggheim, Bjørn, Blomberg, Kristine, Mørch +2 moreopenaire +2 more sources