Results 11 to 20 of about 99,688 (265)

Severe malaria

Malaria Journal, 2022
Severe malaria is a medical emergency. It is a major cause of preventable childhood death in tropical countries. Severe malaria justifies considerable global investment in malaria control and elimination yet, increasingly, international agencies, funders
Nicholas J. White
doaj   +4 more sources

Gut bacterial dysbiosis in pediatric severe malaria associates with post-discharge mortality [PDF]

Nature Communications
Gut microbiota have been implicated in severe malaria in murine models, but their contribution to the pathogenesis of severe malaria in children is unknown.
Olivia J. Bednarski, Sawyer B. Lehman, David Mzinza, Caroline Kazinga, Ruth Namazzi, Robert O. Opoka, Jie Ren, Tuan M. Tran, Terrie E. Taylor, Karl B. Seydel, Chandy C. John, Andrea L. Conroy, Nathan W. Schmidt   +12 more
doaj   +2 more sources

Severe malaria in children and adolescents in Southeast Gabon

BMC Infectious Diseases, 2023
Introduction Malaria remains a significant public health problem in sub-Saharan Africa. Child mortality due to severe malaria remains high in developing countries despite improvements in malaria management and a better understanding of its ...
Judicaël Boris Lendongo Wombo, Euloge Ibinga, Sandrine Lydie Oyegue-Liabagui, Roméo Karl Imboumy Limoukou, Alain Prince Okouga, Franck Mounioko, Sydney Maghendji-Nzondo, Jean Bernard Lekana-Douki, Edgard Brice Ngoungou   +8 more
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Malaria Related Neurocognitive Deficits and Behavioral Alterations

Frontiers in Cellular and Infection Microbiology, 2022
Typical of tropical and subtropical regions, malaria is caused by protozoa of the genus Plasmodium and is, still today, despite all efforts and advances in controlling the disease, a major issue of public health. Its clinical course can present either as
Pamela Rosa-Gonçalves, Pamela Rosa-Gonçalves, Pamela Rosa-Gonçalves, Flávia Lima Ribeiro-Gomes, Flávia Lima Ribeiro-Gomes, Cláudio Tadeu Daniel-Ribeiro, Cláudio Tadeu Daniel-Ribeiro   +6 more
doaj   +1 more source

Artemether for severe malaria [PDF]

Cochrane Database of Systematic Reviews, 2019
In 2011 the World Health Organization (WHO) recommended parenteral artesunate in preference to quinine as first-line treatment for people with severe malaria. Prior to this recommendation many countries, particularly in Africa, had begun to use artemether, an alternative artemisinin derivative.
Esu, Ekpereonne B, Effa, Emmanuel E, Opie, Oko N, Meremikwu, Martin M   +3 more
openaire   +3 more sources

A Comparative Study of Clinical Profiles of Vivax and Falciparum Malaria in Children at a Tertiary Care Centre in Uttarakhand [PDF]

Journal of Clinical and Diagnostic Research, 2013
Background: Falciparum malaria has been constantly associated with high morbidity and mortality for a long time. Vivax malaria, which was once thought to be a relatively benign condition, is appearing in its more malignant form, with severity ...
Ragini Singh, Shruti Kumar, S.K. Rana, Brijesh Thakur, S.P. Singh   +4 more
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Shifts in the clinical epidemiology of severe malaria after scaling up control strategies in Mali

Frontiers in Neurology, 2022
A decrease in malaria incidence following implementation of control strategies such as use of artemisinin-based combination therapies, insecticide-impregnated nets, intermittent preventive treatment during pregnancy and seasonal malaria chemoprevention ...
Drissa Coulibaly, Abdoulaye K. Kone, Bourama Kane, Bouréima Guindo, Bourama Tangara, Mody Sissoko, Fayçal Maiga, Karim Traore, Aichatou Diawara, Amidou Traore, Ali Thera, Mahamadou S. Sissoko, Ogobara K. Doumbo, Mark A. Travassos, Mahamadou A. Thera   +14 more
doaj   +1 more source

Assessing the severity of malaria [PDF]

BMJ, 2003
Life threatening malaria may develop even in patients who appear relatively well at ...
Moore, David AJ, Jennings, Richard M, Doherty, Tom F, Lockwood, Diana N, Chiodini, Peter L, Wright, Stephen G, Whitty, Christopher JM   +6 more
openaire   +3 more sources

Treating severe malaria [PDF]

BMJ, 2005
Rectal artemether may be as good as intravenous quinine E very year over a million children die of malaria in Africa. In many settings, especially rural ones, most fatalities due to malaria occur outside hospital, although a substantial proportion of these children will have made contact with some level of healthcare in their final illness.1 Of those
Whitty, Christopher JM, Ansah, Evelyn, Reyburn, Hugh   +2 more
openaire   +3 more sources

NCR3 polymorphism, haematological parameters, and severe malaria in Senegalese patients [PDF]

PeerJ, 2018
Background Host factors, including host genetic variation, have been shown to influence the outcome of Plasmodium falciparum infection. Genome-wide linkage studies have mapped mild malaria resistance genes on chromosome 6p21, whereas NCR3-412 ...
Alassane Thiam, Sabrina Baaklini, Babacar Mbengue, Samia Nisar, Maryam Diarra, Sandrine Marquet, Mouhamadou Mansour Fall, Michel Sanka, Fatou Thiam, Rokhaya Ndiaye Diallo, Magali Torres, Alioune Dieye, Pascal Rihet   +12 more
doaj   +2 more sources