Results 41 to 50 of about 235,554 (306)

Fluid therapy for severe malaria

The Lancet Infectious Diseases, 2022
Fluid therapy is an important supportive measure for patients with severe malaria. Patients with severe malaria usually have normal cardiac index, vascular resistance, and blood pressure and a small degree of hypovolaemia due to dehydration. Cell hypoxia, reduced kidney function, and acidosis result from microcirculatory compromise and malarial anaemia,
Kalkman, Laura C., Hanscheid, Thomas, Krishna, Sanjeev, Grobusch, Martin P.   +3 more
openaire   +4 more sources

Disease progression in Plasmodium knowlesi malaria is linked to variation in invasion gene family members. [PDF]

, 2014
Emerging pathogens undermine initiatives to control the global health impact of infectious diseases. Zoonotic malaria is no exception. Plasmodium knowlesi, a malaria parasite of Southeast Asian macaques, has entered the human population. P.
A Berry, AA Semenya, AK Bei, Angela Siner, Atique M. Ahmed, B Singh, B Singh, Balbir Singh, BE Barber, BE Barber, C Aurrecoechea, C Daneshvar, Chan Woon Lu, CV Jennings, EV Meyer, G Butcher, G Snounou, H Ozwara, Ing Tien Wong, J Cox-Singh, J Cox-Singh, J Cox-Singh, J Cox-Singh, J Langhorne, J Li, J Rayner, Janet Cox-Singh, JC Barrett, JC Rayner, JC Rayner, JP Cramer, JW Barnwell, K Gunalan, K Hayton, Kenji Hirayama, KS Lee, L Excoffier, LH Bannister, LH Miller, LH Miller, M Willmann, MAM Sallum, Matthias Willmann, Miguel M. Pinheiro, MR Galinski, MR Galinski, N Gomez-Escobar, P Librado, Paul C. Divis, Ramlah Zainudin, RW Moon, S Kumar, S Lopaticki, S Nakazawa, Sanjeev Krishna, Sarina K. Singh-Khaira, Scott B. Millar, Sean Lynch, SL Takala, T William, TM DeSimone, WH Tham   +61 more
core   +3 more sources

Plasma concentration of parasite DNA as a measure of disease severity in falciparum malaria. [PDF]

, 2014
In malaria-endemic areas, Plasmodium falciparum parasitemia is common in apparently healthy children and severe malaria is commonly misdiagnosed in patients with incidental parasitemia.
Chhaganlal, Kajal D, Day, Nicholas PJ, Dondorp, Arjen M, Faiz, M Abul, Gesase, Samwel, Hendriksen, Ilse CE, Imwong, Mallika, Mishra, Saroj, Mohanty, Sanjib, Mtove, George, Seni, Amir, Veenemans, Jacobien, Verhoef, Hans, White, Nicholas J, Woodrow, Charles J   +14 more
core   +1 more source

Randomised feasibility study of an intestinal adsorbent in acute diarrhoea in The Gambia

BMJ Paediatrics Open
Background Diarrhoea remains a leading cause of death in children. An intestinal adsorbent may reduce diarrhoea duration and severity.Methods Randomised controlled feasibility trial with two phases: phase 1 (0–4 hours and double-blind) and phase 2 (up to
Elena Markaryan, Matthew Dodd, Stephen Allen, Carol Howell, Angela Allen, Paul Rahden, Abdoulie Fatty, Momodou Lamin Jobarteh, Abdoulwahab Sallah, Ebrahim Jaiteh, Doreen Umoh, Fanta Bass, Radovan Hnatič   +12 more
doaj   +1 more source

Advocating an attack against severe malaria: a cost-effectiveness analysis

BMC Public Health, 2020
Background A recent study found that the gut microbiota, Lactobacillus and Bifidobacterium, have the ability to modulate the severity of malaria. The modulation of the severity of malaria is not however, the typical focal point of most widespread ...
Scott Greenhalgh, Veda Chandwani
doaj   +1 more source

Severe and benign Plasmodium vivax malaria in Emberá (Amerindian) children and adolescents from an endemic municipality in Western Colombia

Journal of Infection and Public Health, 2016
Summary: Malaria in children is still an important public health problem in endemic areas of South-East Asia and Latin America. Certain forms of the disease, such as Plasmodium vivax severe malaria, are still neglected.
Diego A. Medina-Morales, Estefanía Montoya-Franco, Viviana d.P. Sanchez-Aristizabal, Jorge E. Machado-Alba, Alfonso J. Rodríguez-Morales   +4 more
doaj   +1 more source

Evaluating the effectiveness of IPTi on malaria using routine health information from sentinel health centres in southern Tanzania. [PDF]

, 2011
BACKGROUND\ud \ud Intermittent preventive treatment of malaria in infants (IPTi) consists of the administration of a treatment dose of sulphadoxine-pyrimethamine (SP) at the time of routine vaccinations.
Alonso, Pedro, Armstrong Schellenberg, Joanna R M, Chemba, Mwajuma, Maokola, Werner, Mshinda, Hassan, Schellenberg, David, Shirima, Kizito, Tanner, Marcel, Willey, Barbara A   +8 more
core   +5 more sources

Severe malaria intervention status in Nigeria: workshop meeting report

Malaria Journal
Nigeria accounts for 39% of global malaria deaths in children under 5 years of age and the effective management of severe malaria is a health priority.
Emmanuel Shekarau, Miriam Uzoanya, Nnenna Ogbulafor, Severe Malaria Working Group   +3 more
doaj   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Association of ABO blood group with severe falciparum malaria in adults: case control study and meta-analysis

Malaria Journal, 2011
Background Erythrocyte-associated antigenic polymorphisms or their absence have perhaps evolved in the human population to protect against malarial infection. Studies in various populations consistently demonstrate that blood group 'O' confers resistance
Tripathy Rina, Sahu Aditya N, Panda Santosh K, Panda Aditya K, Ravindran Balachandran, Das Bidyut K   +5 more
doaj   +1 more source