Cost-effectiveness of parenteral artesunate for treating children with severe malaria in sub-Saharan Africa. [PDF]
OBJECTIVE: To explore the cost-effectiveness of parenteral artesunate for the treatment of severe malaria in children and its potential impact on hospital budgets. METHODS: The costs of inpatient care of children with severe malaria were assessed in four
Ngum, WP +52 more
core +1 more source
Background & Objectives: Classically associated with Plasmodium falciparum, neurological complications in severe malaria is associated with increased morbidity and mortality.
Sohaib Ahmad +7 more
doaj +1 more source
The age patterns of severe malaria syndromes in sub-Saharan Africa across a range of transmission intensities and seasonality settings. [PDF]
BACKGROUND: A greater understanding of the relationship between transmission intensity, seasonality and the age-pattern of malaria is needed to guide appropriate targeting of malaria interventions in different epidemiological settings.
Arantxa Roca-Feltrer +18 more
core +1 more source
Decreasing incidence of severe malaria and community-acquired bacteraemia among hospitalized children in Muheza, north-eastern Tanzania, 2006-2010. [PDF]
BACKGROUND: The annual incidence and temporal trend of severe malaria and community-acquired bacteraemia during a four-year period in Muheza, Tanzania was assessed.
Dondorp, AM +38 more
core +1 more source
Imported Plasmodium vivax malaria with severe thrombocytopaenia: can it be severe malaria or not? [PDF]
Thrombocytopaenia is the most frequent malaria-associated haematologic alteration observed with all five Plasmodium parasites causing disease in humans. Although not included in the World Health Organization criteria for severe Plasmodium falciparum malaria, severe thrombocytopaenia has been increasingly mentioned as an indicator of P.
S. Antinori +6 more
openaire +3 more sources
Feasibility and acceptability of injectable artesunate for the treatment of severe malaria in the Democratic Republic of Congo [PDF]
The Democratic Republic of the Congo (DRC) changed its national policy for the treatment of severe malaria in both children and adults in 2012 from intravenous quinine to injectable artesunate.
Lengeler, Christian +13 more
core +1 more source
Randomised feasibility study of an intestinal adsorbent in acute diarrhoea in The Gambia
Background Diarrhoea remains a leading cause of death in children. An intestinal adsorbent may reduce diarrhoea duration and severity.Methods Randomised controlled feasibility trial with two phases: phase 1 (0–4 hours and double-blind) and phase 2 (up to
Elena Markaryan +12 more
doaj +1 more source
Clinical factors for severity of Plasmodium falciparum malaria in hospitalized adults in Thailand. [PDF]
Plasmodium falciparum is a major cause of severe malaria in Southeast Asia, however, there is limited information regarding clinical factors associated with the severity of falciparum malaria from this region.
Patrick Sagaki +7 more
doaj +1 more source
Relation between Increased IL-10 Levels and Malaria Severity: A Systematic Review and Meta-Analysis
The roles of anti-inflammatory cytokines in the pathogenesis of severe malaria have been widely studied, and the role of IL-10 in the pathogenesis of severe malaria remains unclear.
Phoomjai Sornsenee +5 more
doaj +1 more source
Invasive Bacterial Co-infection in African Children with Plasmodium falciparum Malaria: A Systematic Review. [PDF]
Severe malaria remains a major cause of pediatric hospital admission across Africa. Invasive bacterial infection (IBI) is a recognized complication of Plasmodium falciparum malaria, resulting in a substantially worse outcome.
Maitland, Kathryn +4 more
core +2 more sources

